Structural and functional similarities of bovine alpha-crystallin and mouse small heat-shock protein. A family of chaperones.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Protein structure: A practical approach

1990 • 2,071 citations

Alpha-crystallin can function as a molecular chaperone.

1992 • 1,822 citations

Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin.

1982 • 792 citations

Transglutaminases

1984 • 589 citations

αB-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain

1989 • 546 citations

αB subunit of lens-specific protein α-crystallin is present in other ocular and non-ocular tissues

1989 • 538 citations

Transglutaminase is essential in receptor-mediated endocytosis of α2-macroglobulin and polypeptide hormones

1980 • 535 citations

Alpha B-crystallin is a small heat shock protein.

1991 • 526 citations

Induction and activation of tissue transglutaminase during programmed cell death

1987 • 467 citations

Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II.

1992 • 464 citations

Evolution of the alpha-crystallin/small heat-shock protein family.

1993 • 464 citations

A 25-kD inhibitor of actin polymerization is a low molecular mass heat shock protein.

1991 • 445 citations

Sensitivity of circular dichroism to protein tertiary structure class

1983 • 412 citations

Expression of the murine alpha B-crystallin gene is not restricted to the lens.

1989 • 377 citations

Dynamic changes in the structure and intracellular locale of the mammalian low-molecular-weight heat shock protein.

1988 • 356 citations

The Amino‐Acid Sequence of the αA₂ Chain of Bovine α‐Crystallin

1973 • 304 citations

Sequence and organization of genes encoding the human 27 kDa heat shock protein

1986 • 299 citations

Cellular distribution of alpha B-crystallin in non-lenticular tissues.

1990 • 295 citations

Isolation of cDNAs of scrapie-modulated RNAs by subtractive hybridization of a cDNA library.

1988 • 286 citations

Formation of Cytoplasmic Heat Shock Granules in Tomato Cell Cultures and Leaves

1983 • 269 citations

Characterization and purification of the small 28,000-dalton mammalian heat shock protein.

1987 • 263 citations

Accumulation of alpha B-crystallin in central nervous system glia and neurons in pathologic conditions.

1992 • 259 citations

Immunoreactive αA crystallin in rat non-lenticular tissues detected with a sensitive immunoassay method

1991 • 220 citations

αB crystallin expression in nonlenticular tissues and selective presence in ubiquitinated inclusion bodies in human disease

1992 • 206 citations

Identification of the phosphorylation sites of the murine small heat shock protein hsp25

1991 • 199 citations

Tissue distribution and developmental profiles of immunoreactive αB crystallin in the rat determined with a sensitive immunoassay system

1991 • 193 citations

Hypertonic stress induces αB-crystallin expression

1992 • 187 citations

Copurification of small heat shock protein with alpha B crystallin from human skeletal muscle.

1992 • 184 citations

The Amino‐Acid Sequence of the αB₂ Chain of Bovine α‐Crystallin

1974 • 182 citations

Domain structure and evolution in α‐crystallins and small heat‐shock proteins

1985 • 180 citations

α-Crystallin. The isolation and characterization of distinct macromolecular fractions

1971 • 174 citations

Calf lens α-crystallin quaternary structure

1986 • 167 citations

αB-Crystallin is present in reactive glia in Creutzfeldt-Jakob disease

1992 • 165 citations

Alfalfa heat shock genes are differentially expressed during somatic embryogenesis

1991 • 152 citations

Heat shock protein 27 and alpha B-crystallin can form a complex, which dissociates by heat shock.

1992 • 151 citations

Eye Lens Proteins and Transparency: From Light Transmission Theory to Solution X-Ray Structural Analysis

1988 • 139 citations

Micellar subunit assembly in a three-layer model of oligomeric alpha-crystallin.

1991 • 133 citations

Some aspects of the phosphorylation of α‐crystallin A

1986 • 129 citations

Electron microscope observations on some structural proteins of the chick lens

1972 • 124 citations

Ultrastructural and biochemical analysis of the stress granule in chicken embryo fibroblasts.

1988 • 121 citations

Expression and aggregation of recombinant αA-crystallin and its two domains

1992 • 116 citations

Genes for Low-Molecular-Weight Heat Shock Proteins of Soybeans: Sequence Analysis of a Multigene Family

1985 • 114 citations

Molecular cloning, sequencing and expression in Escherichia coli of the 25‐kDa growth‐related protein of Ehrlich ascites tumor and its homology to mammalian stress proteins

1989 • 106 citations

Tissue-specific expression of the heat shock protein HSP27 during Drosophila melanogaster development.

1990 • 105 citations

Splitting and recombination of α-crystallin

1962 • 103 citations

Apoptosis: a potential role for cytosolic transglutaminase and its importance in tumour progression

1991 • 96 citations

Heat‐induced changes in the conformation of α‐ and β‐crystalline: Unique thermal stability of α‐crystallin

1988 • 95 citations

Dogfish alpha-crystallin sequences. Comparison with small heat shock proteins and Schistosoma egg antigen.

1988 • 93 citations

The interrelationship between monomeric, oligomeric and polymeric α-crystallin in the calf lens nucleus

1979 • 92 citations

Ultrastructural localization of aA-crystallin to the bovine lens fiber cell cytoskeleton

1991 • 83 citations

Cardiac alpha-crystallin

1990 • 79 citations

The phosphorylation sites of the B2 chain of bovine α-crystallin

1987 • 77 citations

Primary structures of the α‐crystallin A chains of twenty‐eight mammalian species, chicken and frog

1984 • 77 citations

Complete structure of the hamster αA crystallin gene

1985 • 75 citations

Supramolecular structure of the recombinant murine small heat shock protein hsp25

1991 • 75 citations

A role for transglutaminase in glucose-stimulated insulin release from the pancreatic β-cell

1986 • 74 citations

The Quaternary Structure of Bovine α‐Crystallin

1979 • 70 citations

The carboxy‐terminal lysine of αB‐crystallin is an amine‐donor substrate for tissue transglutaminase

1992 • 68 citations

A Model for the Architecture of α-Crystallin

1979 • 66 citations

Stepwise dissociation/denaturation and reassociation/renaturation of bovine α-crystallin in urea and guanidine hydrochloride: Sedimentation, fluorescence, near-ultraviolet and far-ultraviolet circular dichroism studies

1982 • 63 citations

Cardiac alpha-crystallin

1990 • 62 citations

Characterization of HSP27 and three immunologically related polypeptides during Drosophila development

1988 • 61 citations

Circular dichroism and optical rotatory dispersion of the aggregates of purified polypeptides of alpha-crystallin

1974 • 57 citations

Expression of αB-crystallin in the developing rat kidney

1991 • 56 citations

Translocation and induction of αB crystallin by heat shock in rat glioma (GA-1) cells

1992 • 55 citations

Specificity of alpha crystallin binding to the lens membrane

1990 • 49 citations

The nuclear‐coded chloroplast 22‐kDa heat‐shock protein of Chlamydomonas

1989 • 47 citations

Evidence for the localization of the nuclear‐coded 22‐kDa heat‐shock protein in a subfraction of thylakoid membranes

1991 • 43 citations

Ubiquitin—protein conjugates and αB crystallin are selectively present in cells undergoing major cytomorphological reorganisation in early chicken embryos

1991 • 43 citations

Relocalization of αB‐crystallin by heat shock in ovarian carcinoma cells

1992 • 40 citations

On the structure of α-crystallin: Construction of hybrid molecules and homopolymers

1989 • 39 citations

Folding-unfolding and aggregation-dissociation of bovine α-crystallin subunits; evidence for unfolding intermediates of the αA subunits

1989 • 36 citations

Electron microscopy of native and reconstituted alpha crystallin aggregates

1988 • 34 citations

Loss of high-affinity membrane binding of bovine nuclear α-crystallin

1989 • 34 citations

Studies of the small heat shock proteins of Caenorhabditis elegans using anti‐peptide antibodies

1991 • 27 citations

Specific dissociation of αB subunits from α-crystallin

1988 • 23 citations

βB1 crystallin is an amine-donor substrate for tissue transglutaminase

1987 • 20 citations

Characterization of the elastase inhibitor properties of α-crystallin and the water-insoluble fraction from bovine lens

1992 • 16 citations

Expression, synthesis, and phosphorylation of HSP28 family during development and decay of thermotolerance in CHO plateau‐phase cells

1992 • 14 citations