Nanos and pumilio establish embryonic polarity in Drosophila by promoting posterior deadenylation of hunchback mRNA

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

A gradient of bicoid protein in Drosophila embryos

1988 • 1,015 citations

Nanos is the localized posterior determinant in Drosophila

1991 • 510 citations

Translational regulation of oskar mRNA by Bruno, an ovarian RNA-binding protein, is essential

1995 • 451 citations

Binding of pumilio to maternal hunchback mRNA is required for posterior patterning in drosophila embryos

1995 • 419 citations

RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanos

1991 • 391 citations

Localization of nanos RNA controls embryonic polarity

1992 • 391 citations

Organization of anterior pattern in the Drosophila embryo by the maternal gene bicoid

1986 • 386 citations

Regulation of the Drosophila segmentation gene hunchback by two maternal morphogenetic centres

1988 • 366 citations

The maternal gene nanos has a central role in posterior pattern formation of the Drosophila embryo

1991 • 349 citations

The 3'-untranslated regions of c-mos and cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation.

1994 • 330 citations

Translational regulation of nanos by RNA localization

1994 • 307 citations

The Drosophila posterior-group gene nanos functions by repressing hunchback activity

1989 • 301 citations

A mRNA localized to the vegetal cortex of Xenopus oocytes encodes a protein with a nanos-like zinc finger domain

1993 • 260 citations

A morphogenetic gradient of hunchback protein organizes the expression of the gap genes Krüppel and knirps in the early Drosophila embryo

1990 • 258 citations

Regulated polyadenylation controls mRNA translation during meiotic maturation of mouse oocytes.

1989 • 248 citations

Transient translational silencing by reversible mRNA deadenylation

1992 • 239 citations

Coordinate Initiation of Drosophila Development by Regulated Polyadenylation of Maternal Messenger RNAs

1994 • 236 citations

Genetics of nanos localization in Drosophila

1994 • 234 citations

Translational control of maternal glp-1 mRNA establishes an asymmetry in the C. elegans embryo

1994 • 231 citations

Differing strategies for organizing anterior and posterior body pattern in Drosophila embryos

1989 • 222 citations

15 Translational Control of Developmental Decisions

2000 • 222 citations

Pumilio is essential for function but not for distribution of the Drosophila abdominal determinant Nanos.

1992 • 203 citations

Posterior segmentation of the Drosophila embryo in the absence of a maternal posterior organizer gene

1989 • 198 citations

Structure of the Drosophila BicaudalD protein and its role in localizing the posterior determinant nanos

1989 • 185 citations

Mutually repressive interactions between the gap genes giant and Krüppel define middle body regions of the Drosophila embryo

1991 • 159 citations

Spatial regulation of the gap gene giant during Drosophila development

1991 • 157 citations

Interactions of the Drosophila gap gene giant with maternal and zygotic pattern-forming genes

1991 • 152 citations

Deadenylation of maternal mRNAs during Xenopus oocyte maturation does not require specific cis-sequences: a default mechanism for translational control.

1990 • 152 citations

The Drosophila pumilio gene: an unusually long transcription unit and an unusual protein

1992 • 144 citations

Identification ofcis-Acting Sequences That ControlnanosRNA Localization

1996 • 124 citations

Autonomous determination of anterior structures in the early Drosophila embryo by the bicoid morphogen

1990 • 121 citations

Rapid and sensitive analysis of mRNA polyadenylation states by PCR.

1995 • 108 citations

The Drosophila gene knirps-related is a member of the steroid-receptor gene superf amily

1988 • 105 citations

Mutations that perturb poly(A)-dependent maternal mRNA activation block the initiation of development

1996 • 83 citations

Non-radioactive in situ hybridization

1987 • 78 citations

Evolutionary conservation of sequence elements controlling cytoplasmic polyadenylylation.

1996 • 71 citations

The 3' untranslated region of localized maternal messages contains a conserved motif involved in mRNA localization.

1992 • 64 citations