Transient translational silencing by reversible mRNA deadenylation

Gene Activity in Early Development

1968 • 1,725 citations

Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences

1988 • 691 citations

The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.

1989 • 601 citations

Nucleotide sequence of a full-length cDNA for mousecytosketetal β-actin raRNA

1986 • 556 citations

Steps in the processing of Ad2 mRNA: Poly(A)+ Nuclear sequences are conserved and poly(A) addition precedes splicing

1978 • 478 citations

THE PATHWAY OF EUKARYOTIC mRNA FORMATION

1983 • 429 citations

Poly(A) elongation during Xenopus oocyte maturation is required for translational recruitment and is mediated by a short sequence element.

1989 • 412 citations

RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanos

1991 • 391 citations

Translational Blockade Imposed by Cytokine-Derived UA-Rich Sequences

1989 • 347 citations

Poly(A) addition during maturation of frog oocytes: distinct nuclear and cytoplasmic activities and regulation by the sequence UUUUUAU.

1989 • 332 citations

Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system.

1988 • 324 citations

Changes in state of adenylation and time course of degradation of maternal mRNAs during oocyte maturation and early embryonic development in the mouse

1988 • 304 citations

Hypoxanthine-guanine phosphoribosyltransferase genes of mouse and Chinese hamster: construction and sequence analysis of cDNA recombinants

1982 • 295 citations

Regulated polyadenylation controls mRNA translation during meiotic maturation of mouse oocytes.

1989 • 248 citations

Gene Activity in Early Development

1970 • 236 citations

Protamine 3'-untranslated sequences regulate temporal translational control and subcellular localization of growth hormone in spermatids of transgenic mice.

1989 • 235 citations

Meiotic maturation of mouse oocytes triggers the translation and polyadenylation of dormant tissue-type plasminogen activator mRNA.

1987 • 211 citations

Changes in total RNA, polyadenylated RNA, and actin mRNA during meiotic maturation of mouse oocytes

1985 • 202 citations

Sequence-specific adenylations and deadenylations accompany changes in the translation of maternal messenger RNA after fertilization of Spisula oocytes

1983 • 190 citations

Antisense RNA Directed Against the 3′ Noncoding Region Prevents Dormant mRNA Activation in Mouse Oocytes

1988 • 174 citations

Translational control by cytoplasmic polyadenylation during Xenopus oocyte maturation: characterization of cis and trans elements and regulation by cyclin/MPF.

1990 • 165 citations

Translational control during early development

1991 • 163 citations

Plasminogen activator in mouse and rat oocytes: Induction during meiotic maturation

1985 • 163 citations

Molecular cloning of complementary DNA to mouse tissue plasminogen activator mRNA and its expression during F9 teratocarcinoma cell differentiation.

1988 • 156 citations

Interactive effects of the tumor necrosis factor promoter and 3'-untranslated regions.

1991 • 153 citations

In the beginning is the end: regulation of poly(A) addition and removal during early development

1990 • 153 citations

Deadenylation of maternal mRNAs during Xenopus oocyte maturation does not require specific cis-sequences: a default mechanism for translational control.

1990 • 152 citations

Maturation-specific polyadenylation and translational control: diversity of cytoplasmic polyadenylation elements, influence of poly(A) tail size, and formation of stable polyadenylation complexes.

1990 • 144 citations

Xfin: an embryonic gene encoding a multifingered protein in Xenopus.

1987 • 139 citations

Repeating structure of cytoplasmic poly(A)-ribonucleoprotein.

1980 • 134 citations

Poly(A) removal during oocyte maturation: a default reaction selectively prevented by specific sequences in the 3' UTR of certain maternal mRNAs.

1990 • 128 citations

Isolation of novel murine maternal mRNAs regulated by cytoplasmic polyadenylation.

1992 • 105 citations

Half-lives and relative amounts of stored and polysomal ribosomes and poly(A)+ RNA in mouse oocytes

1983 • 84 citations

Widespread changes in the translation and adenylation of maternal messenger RNAs following fertilization of Spisula oocytes

1987 • 83 citations

The structure of the TATA-less rat tissue-type plasminogen activator gene. Species-specific sequence divergences in the promoter predict differences in regulation of gene expression.

1990 • 64 citations