Role of cAMP-dependent protein kinase A activity in endothelial cell cytoskeleton rearrangement

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

cAMP-DEPENDENT PROTEIN KINASE: FRAMEWORK FOR A DIVERSE FAMILY OF REGULATORY ENZYMES

1990 • 1,121 citations

Inhibition by cAMP of Ras-Dependent Activation of Raf

1993 • 955 citations

Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3′,5′-Monophosphate

1993 • 939 citations

Mammalian Membrane-bound Adenylyl Cyclases

1995 • 722 citations

Adenylyl cyclases and the interaction between calcium and cAMP signalling

1995 • 594 citations

Regulation of endothelial cell gap formation and barrier dysfunction: Role of myosin light chain phosphorylation

1995 • 550 citations

Structure and Function of Cyclic Nucleotide-Dependent Protein Kinases

1994 • 442 citations

Caldesmon, a novel regulatory protein in smooth muscle and nonmuscle actomyosin systems

1991 • 353 citations

Mechanism of inhibition of Raf-1 by protein kinase A.

1994 • 311 citations

Role of endothelial cell cytoskeleton in control of endothelial permeability.

1982 • 310 citations

Negative Regulation of Raf-1 by Phosphorylation of Serine 621

1996 • 215 citations

cAMP-dependent protein kinase inhibits the mitogenic action of vascular endothelial growth factor and fibroblast growth factor in capillary endothelial cells by blocking Raf activation

1997 • 200 citations

Myosin light chain kinase in endothelium: molecular cloning and regulation.

1997 • 200 citations

Regulation of endothelial cell gap formation and paracellular permeability.

1995 • 165 citations

Adducin Regulation

1996 • 164 citations

Protein kinase C phosphorylates caldesmon₇₇ and vimentin and enhances albumin permeability across cultured bovine pulmonary artery endothelial cell monolayers

1992 • 163 citations

A role for MAP kinase in differentiated smooth muscle contraction evoked by α-adrenoceptor stimulation

1998 • 157 citations

Signal transduction and regulation of lung endothelial cell permeability. Interaction between calcium and cAMP

1998 • 150 citations

Adherent neutrophils activate endothelial myosin light chain kinase: role in transendothelial migration

1998 • 143 citations

Mitosis-specific phosphorylation causes 83K non-muscle caldesmon to dissociate from microfilaments

1990 • 130 citations

Inhibition of glycogenolysis in isolated rat hepatocytes by the Rp diastereomer of adenosine cyclic 3‘,5‘-phosphorothioate.

1983 • 111 citations

Regulation of Endothelial Barrier Function by the cAMP-Dependent Protein Kinase

2000 • 107 citations

Control of cAMP in lung endothelial cell phenotypes. Implications for control of barrier function

1999 • 107 citations

Biochemical Regulation of the Nonmuscle Myosin Light Chain Kinase Isoform in Bovine Endothelium

1998 • 105 citations

Activation of MAP kinases and phosphorylation of caldesmon in canine colonic smooth muscle.

1996 • 103 citations

Phosphorylation of caldesmon by ERK MAP kinases in smooth muscle

2000 • 102 citations

Regulation of endothelial cell gap formation and barrier function by myosin-associated phosphatase activities

1995 • 100 citations

Protein kinase A activity is required for the budding of constitutive transport vesicles from the trans-Golgi network

1997 • 99 citations

Cyclic-GMP-Mediated Decrease in Permeability of Human Umbilical and Pulmonary Artery Endothelial Cell Monolayers

1994 • 96 citations

Role of Ras-dependent ERK activation in phorbol ester-induced endothelial cell barrier dysfunction

2000 • 93 citations

Role of the Cyclic AMP—Dependent Protein Kinase in Signal Transduction

1989 • 92 citations

Abolition of actin-bundling by phosphorylation of human erythrocyte protein 4.9

1988 • 88 citations

Ca(2+)-inhibitable adenylyl cyclase modulates pulmonary artery endothelial cell cAMP content and barrier function.

1995 • 83 citations

Caldesmon Inhibits Active Crossbridges in Unstimulated Vascular Smooth Muscle

1998 • 81 citations

Restoration of the cAMP second messenger pathway enhances cardiac preservation for transplantation in a heterotopic rat model.

1993 • 81 citations

Cyclic AMP-dependent phosphorylation of filamin in mammalian smooth muscle

1978 • 79 citations

Mechanisms of Cholera Toxin Prevention of Thrombin- and PMA-Induced Endothelial Cell Barrier Dysfunction

1994 • 78 citations

Phosphorylation of caldesmon by mitogen‐activated protein kinase with no effect on Ca2+ sensitivity in rabbit smooth muscle.

1995 • 77 citations

Activation of MAP kinases in airway smooth muscle

1997 • 73 citations

H2O2-induced filamin redistribution in endothelial cells is modulated by the cyclic AMP-dependent protein kinase pathway

1997 • 72 citations

Mammal-specific, ERK-dependent, Caldesmon Phosphorylation in Smooth Muscle

1999 • 68 citations

Antiproliferative effect of elevated glucose in human microvascular endothelial cells

1998 • 58 citations

Role of Tyrosine Phosphorylation in Thrombin-Induced Endothelial Cell Contraction and Barrier Function

1998 • 58 citations

Ca(2+)-inhibitable adenylyl cyclase and pulmonary microvascular permeability

1997 • 54 citations

Caldesmon and a 20-kDa actin-binding fragment of caldesmon inhibit tension development in skinned gizzard muscle fiber bundles.

1993 • 54 citations

The actions of cyclic AMP on biosynthetic processes are mediated indirectly by cyclic AMP-dependent protein kinase

1991 • 52 citations

Mechanisms of pertussis toxin-induced barrier dysfunction in bovine pulmonary artery endothelial cell monolayers

1995 • 43 citations

Both N-terminal myosin-binding and C-terminal actin-binding sites on smooth muscle caldesmon are required for caldesmon-mediated inhibition of actin filament velocity

1997 • 43 citations

Pertussis toxin directly activates endothelial cell p42/p44 MAP kinases via a novel signaling pathway

2001 • 31 citations

Adenosine prevents PMA-induced lung injury via an A2 receptor mechanism

1993 • 27 citations

Evidence against the regulation of caldesmon inhibitory activity by p42/p44^erk mitogen‐activated protein kinase in vitro and demonstration of another caldesmon kinase in intact gizzard smooth muscle

1999 • 26 citations