Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

MicroRNAs

2004 • 33,206 citations

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1993 • 12,238 citations

Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells

2007 • 9,934 citations

Oncomirs — microRNAs with a role in cancer

2006 • 6,877 citations

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

2000 • 4,834 citations

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

1993 • 4,021 citations

A microRNA polycistron as a potential human oncogene

2005 • 3,482 citations

MicroRNA biogenesis: coordinated cropping and dicing

2005 • 2,443 citations

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

2000 • 2,422 citations

MicroRNA maturation: stepwise processing and subcellular localization

2002 • 2,410 citations

Selective Blockade of MicroRNA Processing by Lin28

2008 • 1,422 citations

Widespread microRNA repression by Myc contributes to tumorigenesis

2007 • 1,300 citations

The tumor suppressor microRNA let-7 represses the HMGA2 oncogene

2007 • 1,133 citations

Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation

2007 • 1,092 citations

The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA

1997 • 844 citations

Extensive post-transcriptional regulation of microRNAs and its implications for cancer

2006 • 835 citations

Heterochronic Mutants of the Nematode Caenorhabditis elegans

1984 • 792 citations

A custom microarray platform for analysis of microRNA gene expression

2004 • 733 citations

Specialization and evolution of endogenous small RNA pathways

2007 • 694 citations

Nanog and transcriptional networks in embryonic stem cell pluripotency

2007 • 579 citations

The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a

2007 • 540 citations

Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells

2007 • 461 citations

The Transcriptome Profile of Human Embryonic Stem Cells as Defined by SAGE

2004 • 430 citations

A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans

1989 • 356 citations

Depletion of Human Micro-RNA miR-125b Reveals That It Is Critical for the Proliferation of Differentiated Cells but Not for the Down-regulation of Putative Targets during Differentiation

2005 • 336 citations

Retracted: Post‐transcriptional regulation of the let‐7 microRNA during neural cell specification

2006 • 310 citations

Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay

1997 • 302 citations

Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency

2007 • 273 citations

Micro-RNA Regulation of the Mammalian lin-28 Gene during Neuronal Differentiation of Embryonal Carcinoma Cells

2005 • 263 citations

[15] Preparation of extracts from higher eukaryotes

1990 • 252 citations

The time of appearance of the C. elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter

2003 • 188 citations

Localization of the Developmental Timing Regulator Lin28 to mRNP Complexes, P-bodies and Stress Granules

2007 • 188 citations

Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse

2003 • 170 citations

Deleted Work

1955 • 0 citations