Ras complements the carboxyl terminus of v-Abl protein in lymphoid transformation

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins

1991 • 1,931 citations

Proteins regulating Ras and its relatives

1993 • 1,930 citations

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow.

1991 • 1,622 citations

Tyrosine Kinase Activity and Transformation Potency of bcr-abl Oncogene Products

1990 • 1,305 citations

RNA tumor viruses

1982 • 833 citations

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

1990 • 767 citations

Requirement for c-ras proteins during viral oncogene transformation

1986 • 680 citations

BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

1993 • 667 citations

Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene

1986 • 489 citations

PDGF induction of tyrosine phosphorylation of GTPase activating protein

1989 • 478 citations

The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

1989 • 427 citations

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.

1991 • 392 citations

c-Abl kinase regulates the protein binding activity of c-Crk.

1994 • 362 citations

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

1991 • 348 citations

An actin-binding function contributes to transformation by the Bcr-Abl oncoprotein of Philadelphia chromosome-positive human leukemias.

1993 • 317 citations

Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites.

1994 • 313 citations

A quantitative assay for transformation of bone marrow cells by Abelson murine leukemia virus.

1976 • 299 citations

Direct transformation of 3T3 cells by Abelson murine leukaemia virus

1975 • 288 citations

Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein.

1991 • 279 citations

The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity [published erratum appears in J Cell Biol 1994 Mar;124(5):865]

1994 • 271 citations

Genetic requirement for Ras in the transformation of fibroblasts and hematopoietic cells by the Bcr-Abl oncogene.

1995 • 268 citations

Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products.

1985 • 266 citations

Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity.

1990 • 264 citations

Nucleotide sequence of Abelson murine leukemia virus genome: structural similarity of its transforming gene product to other onc gene products with tyrosine-specific kinase activity.

1983 • 253 citations

Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk

1994 • 211 citations

Cell Cycle—Regulated Binding of c-Abl Tyrosine Kinase to DNA

1992 • 202 citations

ras and GAP—Who's controlling whom?

1990 • 185 citations

Characterization of mouse monoclonal antibodies specific for friend murine leukemia virus-induced erythroleukemia cells: Friend-specific and FMR-specific antigens

1981 • 184 citations

CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells.

1994 • 182 citations

Sequences of the A-MuLV protein needed for fibroblast and lymphoid cell transformation

1983 • 165 citations

The complete coding sequence of arg defines the Abelson subfamily of cytoplasmic tyrosine kinases.

1990 • 157 citations

Differential Phosphorylation of c-Abl in Cell Cycle Determined by cdc 2 Kinase and Phosphatase Activity

1990 • 157 citations

the Viral and Cellular Forms of the Abelson (Dbl) Oncogene

1988 • 157 citations

An active v-abl protein tyrosine kinase blocks immunoglobulin light-chain gene rearrangement.

1994 • 134 citations

Murine hematopoietic cells with pre-B or pre-B/myeloid characteristics are generated by in vitro transformation with retroviruses containing fes, ras, abl, and src oncogenes.

1986 • 124 citations

Evidence that the Abelson virus protein functions in vivo as a protein kinase that phosphorylates tyrosine.

1981 • 113 citations

A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization

1990 • 112 citations

Abelson murine leukemia virus mutants deficient in kinase activity and lymphoid cell transformation

1980 • 101 citations

BCR First Exon Sequences Specifically Activate the BCR/ABL Tyrosine Kinase Oncogene of Philadelphia ChromosomePositive Human Leukemias

1991 • 97 citations

Functional organization of the Harvey murine sarcoma virus genome

1980 • 91 citations

Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines

1992 • 88 citations

DNA sequence, structure, and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog.

1988 • 67 citations

Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines

1992 • 64 citations

Site-directed deletions of Abelson murine leukemia virus define 3' sequences essential for transformation and lethality

1983 • 57 citations

Oncogene cooperation in lymphocyte transformation: malignant conversion of E mu-myc transgenic pre-B cells in vitro is enhanced by v-H-ras or v-raf but not v-abl.

1989 • 55 citations

Oncogenic Activation of c-ABL by Mutation within Its Last Exon

1993 • 51 citations

Monoclonal antibodies specific for v-abl- and c-abl-encoded molecules

1986 • 50 citations

CRK Protein Binds to Two Guanine Nucleotide-Releasing Proteins for the Ras Family and Modulates Nerve Growth Factor-Induced Activation of Ras in PC12 Cells

1994 • 50 citations

Protein-Tyrosine Kinases Regulate the Phosphorylation, Protein Interactions, Subcellular Distribution, and Activity of p21^rasGTPase-Activating Protein

1991 • 50 citations

Detection of c-abl Tyrosine Kinase Activity In Vitro Permits Direct Comparison of Normal and Altered abl Gene Products

1985 • 46 citations

v-Abl-mediated Apoptotic Suppression Is Associated with SHC Phosphorylation without Concomitant Mitogen-activated Protein Kinase Activation

1995 • 45 citations

Isolation of temperature-sensitive Abelson virus mutants by site-directed mutagenesis.

1987 • 38 citations

Normal Cellular and Transformation-Associated abl Proteins Share Common Sites fOr Protein Kinase C Phosphorylation

1987 • 35 citations

Temperature-sensitive mutants of Abelson murine leukemia virus deficient in protein tyrosine kinase activity

1990 • 33 citations

Notes: bcr/abl and src but Not myc and ras Replace v-abl in Lymphoid Transformation

1990 • 25 citations

Abelson murine leukemia virus variants with increased oncogenic potential

1986 • 21 citations

Oncogene Cooperation in Lymphocyte Transformation: Malignant Conversion of Eμ-myc Transgenic Pre-B Cells In Vitro Is Enhanced by v-H-ras or v-raf but Not v-abl

1989 • 13 citations

Carboxyl-terminal determinants of Abelson protein important for lymphoma induction

1991 • 11 citations

DNA Sequence, Structure, and Tyrosine Kinase Activity of the Drosophila melanogaster Abelson Proto-Oncogene Homolog

1988 • 11 citations

Bone marrow-transforming activity of linker insertion mutants of Abelson murine leukemia virus.

1992 • 6 citations

Pre-B-Cells Transformed by ts Abelson Virus Rearrange κ and γ Genes in Early G1

1995 • 3 citations