DNA sequence, structure, and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

A general method applicable to the search for similarities in the amino acid sequence of two proteins

1970 • 11,049 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1985 • 2,257 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

A thousand and one protein kinases

1987 • 1,066 citations

A rapid single-stranded cloning strategy for producing a sequential series of overlapping clones for use in DNA sequencing: Application to sequencing the corn mitochondrial 18 S rDNA

1985 • 1,051 citations

The Drosophila homology of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless

1987 • 906 citations

The engrailed locus of drosophila: Structural analysis of an embryonic transcript

1985 • 735 citations

Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins

1984 • 686 citations

Easy identification of cDNA clones.

1983 • 587 citations

Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene

1986 • 489 citations

A Noncatalytic Domain Conserved among Cytoplasmic Protein-Tyrosine Kinases Modifies the Kinase Function and Transforming Activity of Fujinami Sarcoma Virus P130^gag-fps

1986 • 478 citations

Sigma factors fromE. coli, B. subtilis, phage SP01, and phage T4 are homologous proteins

1986 • 460 citations

Sevenless , a Cell-Specific Homeotic Gene of Drosophila , Encodes a Putative Transmembrane Receptor with a Tyrosine Kinase Domain

1987 • 421 citations

Alternative 5′ exons in c-abl mRNA

1986 • 290 citations

A convenient and adaptable package of computer programs for DNA and protein sequence management, analysis and homology determination

1984 • 285 citations

Improvements of DNA sequencing gels

1981 • 269 citations

A high speed, high capacity homology matrix: zooming through SV40 and polyoma

1982 • 215 citations

The Drosophila EGF receptor gene homolog: Conservation of both hormone binding and kinase domains

1985 • 202 citations

The nucleotide sequence and the tissue-specific expression of Drosophila c-src

1985 • 201 citations

Structure-independent nucleotide sequence analysis.

1979 • 199 citations

The drosophila ras oncogenes: Structure and nucleotide sequence

1984 • 175 citations

Sequences of the A-MuLV protein needed for fibroblast and lymphoid cell transformation

1983 • 165 citations

Isolation of antibodies for phosphotyrosine by immunization with a v-abl oncogene-encoded protein.

1985 • 163 citations

Activation of the c-abl oncogene by viral transduction or chromosomal translocation generates altered c-abl proteins with similar in vitro kinase properties.

1985 • 162 citations

Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia.

1986 • 160 citations

Isolation of the proto-oncogene c-myb from D. melanogaster

1985 • 157 citations

Cellular RNA homologous to the Abelson murine leukemia virus transforming gene: expression and relationship to the viral sequence.

1983 • 124 citations

Three loci related to the src oncogene and tyrosine-specific protein kinase activity in Drosophila

1983 • 124 citations

A molecular analysis of transformer, a gene in drosophila melanogaster that controls female sexual differentiation

1987 • 119 citations

Nucleotide sequences of the drosophila src and abl homologs: conservation and variability in the src family oncogenes

1983 • 114 citations

Alternative 5′ exons and tissue-specific expression of the Drosophila EGF receptor homolog transcripts

1986 • 106 citations

The Drosophila abelson proto-oncogene homolog: Identification of mutant alleles that have pleiotropic effects late in development

1987 • 105 citations

Lethal effect of the abelson murine leukemia virus transforming gene product

1981 • 101 citations

Primary sequence and developmental expression of a novel Drosophila melanogaster src gene.

1987 • 98 citations

Drosophila melanogaster DNA clones homologous to vertebrate oncogenes: Evidence for a common ancestor to the src and abl cellular genes

1983 • 91 citations

Minimal size plasmids containing an M13 origin for production of single-strand transducing particles.

1984 • 82 citations

The minimum transforming region of v-abl is the segment encoding protein-tyrosine kinase

1985 • 70 citations

Characterization of functional domains of p21 ras by use of chimeric genes.

1985 • 60 citations

Isolation of temperature-sensitive tyrosine kinase mutants of v-abl oncogene by screening with antibodies for phosphotyrosine.

1987 • 57 citations

Tissue Localization of Drosophila melanogaster ras Transcripts during Development

1986 • 54 citations

Proto-oncogenes in Drosophila melanogaster

1987 • 49 citations

Expression of the src and abl cellular oncogenes during development of Drosophila melanogaster.

1984 • 46 citations

Cellular RNA Homologous to the Abelson Murine Leukemia Virus Transforming Gene: Expression and Relationship to the Viral Sequence

1983 • 42 citations

Tissue localization of Drosophila melanogaster ras transcripts during development.

1986 • 37 citations

Functions of the abl oncogene.

1986 • 32 citations

Independence of fushi tarazu expression with respect to cellular density in Drosophila embryos

1987 • 24 citations

Alternative processing and developmental control of the transcripts of the Drosophila abl oncogene homologue.

1985 • 24 citations

Multiple polyadenylation sites in aDrosophilatropomyasin gene are used to generate functional mRNAs

1985 • 22 citations