The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity [published erratum appears in J Cell Biol 1994 Mar;124(5):865]

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

The Regulation of Rabbit Skeletal Muscle Contraction

1971 • 4,491 citations

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1992 • 3,628 citations

Mechanotransduction Across the Cell Surface and Through the Cytoskeleton

1993 • 2,947 citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1991 • 1,317 citations

Identification of a Ten-Amino Acid Proline-Rich SH3 Binding Site

1993 • 1,205 citations

Fluorimetry study of N-(1-pyrenyl)iodoacetamide-labelled F-actin. Local structural change of actin protomer both on polymerization and on binding of heavy meromyosin.

1981 • 811 citations

Structural interaction of cytoskeletal components

1981 • 766 citations

MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium–calmodulin

1992 • 728 citations

Identification of a Protein that Binds to the SH3 Region of Abl and Is Similar to Bcr and GAP-rho

1992 • 553 citations

Identification of a factor in conventional muscle actin preparations which inhibits actin filament self-association

1980 • 473 citations

SDS microslab linear gradient polyacrylamide gel electrophoresis

1978 • 465 citations

An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro

1993 • 451 citations

The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

1989 • 427 citations

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.

1991 • 392 citations

The three-dimensional structure of a glutathione S-transferase from the Mu gene class. Structural analysis of the binary complex of isoenzyme 3-3 and glutathione at 2.2-.ANG. resolution

1992 • 372 citations

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

1991 • 348 citations

SH3 domains direct cellular localization of signaling molecules

1993 • 339 citations

Adhesion plaques of Rous sarcoma virus-transformed cells contain the src gene product.

1980 • 334 citations

Transformation of cells by an inhibitor of phosphatases acting on phosphotyrosine in proteins

1985 • 331 citations

An actin-binding function contributes to transformation by the Bcr-Abl oncoprotein of Philadelphia chromosome-positive human leukemias.

1993 • 317 citations

Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I

1990 • 315 citations

Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo.

1992 • 295 citations

Alternative 5′ exons in c-abl mRNA

1986 • 290 citations

N-terminal mutations activate the leukemogenic potential of the myristoylated form of c-abl.

1989 • 288 citations

Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins.

1991 • 286 citations

The control of actin nucleotide exchange by thymosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cells.

1992 • 285 citations

Modular organization of actin crosslinking proteins

1991 • 282 citations

Polarity of actin at the leading edge of cultured cells

1978 • 268 citations

Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva

1991 • 246 citations

Drosophila abl tyrosine kinase in embryonic CNS axons: A role in axonogenesis is revealed through dosage-sensitive interactions with disabled

1989 • 240 citations

Rous sarcoma virus transforming protein lacking myristic acid phosphorylates known polypeptide substrates without inducing transformation

1986 • 223 citations

Requirement of yeast fimbrin for actin organization and morphogenesis in vivo

1991 • 217 citations

F-actin binding and bundling properties of fimbrin, a major cytoskeletal protein of microvillus core filaments.

1981 • 214 citations

7-Chloro-4-nitrobenzeno-2-oxa-1,3-diazole actin as a probe for actin polymerization.

1981 • 203 citations

Cell Cycle—Regulated Binding of c-Abl Tyrosine Kinase to DNA

1992 • 202 citations

Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation.

1993 • 190 citations

Analysis of the actin-binding domain of alpha-actinin by mutagenesis and demonstration that dystrophin contains a functionally homologous domain.

1992 • 182 citations

[74] Microinjection of early SV40 DNA fragments and T antigen

1980 • 176 citations

Primary structure of the brain alpha-spectrin [published erratum appears in J Cell Biol 1989 Mar;108(3):following 1175]

1989 • 164 citations

The complete coding sequence of arg defines the Abelson subfamily of cytoplasmic tyrosine kinases.

1990 • 157 citations

Gelsolin has three actin-binding sites.

1988 • 156 citations

Modulation of the interaction between G-actin and thymosin beta 4 by the ATP/ADP ratio: possible implication in the regulation of actin dynamics.

1993 • 156 citations

Evidence for functional homology in the F-actin binding domains of gelsolin and alpha-actinin: implications for the requirements of severing and capping.

1992 • 155 citations

Thymosin beta 4 (Fx peptide) is a potent regulator of actin polymerization in living cells.

1992 • 153 citations

The heavy chain of Acanthamoeba myosin IB is a fusion of myosin-like and non-myosin-like sequences.

1987 • 125 citations

Expression and Purification of Glutathione‐S‐Transferase Fusion Proteins

1994 • 121 citations

Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity

1984 • 119 citations

Tyrosine Phosphorylation of Actin in Dictyostelium Associated with Cell-Shape Changes

1993 • 118 citations

The src protein contains multiple domains for specific attachment to membranes.

1990 • 112 citations

A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization

1990 • 112 citations

Pieces in the actin-severing protein puzzle

1988 • 112 citations

Comparative two-dimensional gel analysis and microsequencing identifies gelsolin as one of the most prominent downregulated markers of transformed human fibroblast and epithelial cells.

1990 • 99 citations

Changes in amino-terminal sequences of pp60src lead to decreased membrane association and decreased in vivo tumorigenicity

1982 • 97 citations

BCR First Exon Sequences Specifically Activate the BCR/ABL Tyrosine Kinase Oncogene of Philadelphia ChromosomePositive Human Leukemias

1991 • 97 citations

Smooth muscle caldesmon is an extended flexible monomeric protein in solution that can readily undergo reversible intra- and intermolecular sulfhydryl cross-linking. A mechanism for caldesmon's F-actin bundling activity.

1987 • 97 citations

An electrophoretic procedure for detecting proteins that bind actin monomers

1989 • 86 citations

Crystallization of glutathione S-transferase from human placenta

1990 • 80 citations

The minimum transforming region of v-abl is the segment encoding protein-tyrosine kinase

1985 • 70 citations

Point Mutations in theablSH2 Domain Coordinately Impair Phosphotyrosine Binding In Vitro and Transforming Activity In Vivo

1992 • 70 citations

Stage-specific tyrosine phosphorylation of actin in Dictyostelium discoideum cells

1992 • 65 citations

Reinvestigation of the inhibition of actin polymerization by profilin.

1985 • 57 citations

Detection of the v-abl gene product at cell-substratum contact sites in Abelson murine leukemia virus-transformed fibroblasts

1984 • 57 citations

A common theme in the amino acid sequences of actin and many actin-binding proteins?

1989 • 54 citations

Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line.

1992 • 51 citations

Are the conserved sequences in segment 1 of gelsolin important for binding actin?

1992 • 45 citations

Selective binding of gelsolin to actin monomers containing ADP

1993 • 40 citations

Structural principles of actin-binding proteins

1989 • 36 citations

Normal Cellular and Transformation-Associated abl Proteins Share Common Sites fOr Protein Kinase C Phosphorylation

1987 • 35 citations

The src Protein Contains Multiple Domains for Specific Attachment to Membranes

1990 • 30 citations

P210 BCR-ABL is complexed to P160 BCR and ph-P53 proteins in K562 cells.

1990 • 26 citations

Nonmyristoylated Abl Proteins Transform a Factor-Dependent Hematopoietic Cell Line

1992 • 19 citations

Evaluation of the binding of Acanthamoeba profilin to pyrene-labeled actin by fluorescence enhancement

1988 • 18 citations

Structural and Functional Relationship between the Membrane and the Cytoskeleton in Brush Border Microvilli

1983 • 6 citations