Decreased DNA Repair Efficiency by Loss or Disruption of p53 Function Preferentially Affects Removal of Cyclobutane Pyrimidine Dimers from Non-transcribed Strand and Slow Repair Sites in Transcribed Strand

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1990 • 3,896 citations

Interaction of the p53-Regulated Protein Gadd45 with Proliferating Cell Nuclear Antigen

1994 • 941 citations

The p53 Network

1998 • 731 citations

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3.

1994 • 666 citations

Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair

1999 • 571 citations

p53 modulation of TFIIH–associated nucleotide excision repair activity

1995 • 555 citations

Nucleotide Excision Repair in Mammalian Cells

1997 • 446 citations

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

1995 • 409 citations

Expression of Wild-type p53 Is Required for Efficient Global Genomic Nucleotide Excision Repair in UV-irradiated Human Fibroblasts

1997 • 365 citations

Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage.

1995 • 365 citations

Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance.

1995 • 351 citations

A Viral Mechanism for Inhibition of p300 and PCAF Acetyltransferase Activity

1999 • 343 citations

Slow Repair of Pyrimidine Dimers at p53 Mutation Hotspots in Skin Cancer

1994 • 301 citations

DNA excision repair pathways

1997 • 258 citations

Nucleotide excision repair: From E. coli to man

1999 • 230 citations

Effect of DNA lesions on transcription elongation

1999 • 229 citations

Isolation and growth of human mammary epithelial cells

1985 • 185 citations

Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7.

1995 • 178 citations

Hepatitis B virus X protein inhibits nucleotide excision repair

1999 • 166 citations

Where transcription meets repair

1994 • 148 citations

Introduction: p53 – the first twenty years

1999 • 142 citations

Human fibroblasts expressing the human papillomavirus E6 gene are deficient in global genomic nucleotide excision repair and sensitive to ultraviolet irradiation.

1998 • 120 citations

DNA repair domains within a human gene: selective repair of sequences near the transcription initiation site.

1996 • 116 citations

Repair and Transcription: Collision or collusion?

1994 • 97 citations

Hepatitis B x Protein Inhibits p53-dependent DNA Repair in Primary Mouse Hepatocytes

1998 • 78 citations

Wildtype p53 is required for heat shock and ultraviolet light enhanced repair of a UV-damaged reporter gene

1997 • 71 citations

Potential roles for p53 in nucleotide excision repair

1999 • 68 citations

Genomic instability: environmental invasion and the enemies within

1998 • 66 citations

Transcription factor IIH: A key player in the cellular response to DNA damage

1999 • 60 citations

Influence of p53 tumor suppressor protein on bias of DNA repair and apoptotic response in human cells

1999 • 59 citations

Sequence-specific and Domain-specific DNA Repair in Xeroderma Pigmentosum and Cockayne Syndrome Cells

1997 • 56 citations

Lack of Gene- and Strand-Specific DNA Repair in RNA Polymerase III-Transcribed Human tRNA Genes

1997 • 55 citations

Faculty DNA polymerase δ/ɛ-mediated excision repair in response to γ radiation or ultraviolet light in p53-deficient fibroblast strains from affected members of a cancer-prone family with Li-Fraumeni syndrome

1996 • 53 citations

DNA repair in human cells: quantitative assessment of bulky anti-BPDE-DNA adducts by non-competitive immunoassays

1995 • 53 citations

Nucleosome Unfolding during DNA Repair in Normal and Xeroderma Pigmentosum (Group C) Human Cells

1998 • 30 citations

Transcription response and nucleotide excision repair

1998 • 24 citations

Technologies for detection of DNA damage and mutations

1997 • 21 citations