A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct.

1979 • 975 citations

Transcriptional regulation of hemoglobin switching in chicken embryos.

1981 • 800 citations

Iron-Responsive Elements: Regulatory RNA Sequences That Control mRNA Levels and Translation

1988 • 707 citations

Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences

1988 • 691 citations

The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.

1989 • 601 citations

A stem-loop in the 3′ untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm

1988 • 565 citations

Identification of an AUUUA-Specific Messenger RNA Binding Protein

1989 • 515 citations

A specific mRNA binding factor regulates the iron-dependent stability of cytoplasmic transferrin receptor mRNA

1989 • 511 citations

Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs

1986 • 490 citations

Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.

1983 • 446 citations

Determinants of messenger RNA stability

1987 • 414 citations

The primary transcription unit of the mouse β-Major globin gene

1981 • 358 citations

Translation is required for regulation of histone mRNA degradation

1987 • 345 citations

Autoregulated instability of β-tubulin mRNAs by recognition of the nascent amino terminus of βtubulin

1988 • 345 citations

Classification and purification of proteins of heterogeneous nuclear ribonucleoprotein particles by RNA-binding specificities.

1988 • 327 citations

Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system.

1988 • 324 citations

Rapid Cytoplasmic Turnover of c-myc mRNA: Requirement of the 3′ Untranslated Sequences

1987 • 302 citations

Identification and nucleotide sequence of a human locus homologous to the v-myc oncogene of avian myelocytomatosis virus MC29

1983 • 287 citations

Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian cells.

1985 • 262 citations

A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA.

1989 • 244 citations

GM-CSF and oncogene mRNA stabilities are independently regulated in trans in a mouse monocytic tumor

1988 • 227 citations

A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif

1988 • 187 citations

Cell-cycle regulation of histone gene expression

1986 • 183 citations

Determinants that contribute to cytoplasmic stability of human c-fos and beta-globin mRNAs are located at several sites in each mRNA.

1988 • 178 citations

Analysis of interferon mRNA in human fibroblast cells induced to produce interferon.

1981 • 147 citations

Sequences that confer β-tubulin autoregulation through modulated mRNA stability reside within exon 1 of a β-tubulin mRNA

1987 • 129 citations

Posttranscriptional gene regulation and specific binding of the nonhistone protein HMG-I by the 3' untranslated region of bovine interleukin 2 cDNA.

1987 • 128 citations

Multiple determinants of eukaryotic mRNA stability.

1989 • 118 citations

Stability of globin mRNA in terminally differentiating murine erythroleukemia cells

1981 • 108 citations

A Uridylate Tract Mediates Efficient Heterogeneous Nuclear Ribonucleoprotein C Protein-RNA Cross-Linking and Functionally Substitutes for the Downstream Element of the Polyadenylation Signal

1990 • 107 citations

Poly(A) Tail Shortening Is the Translation-Dependent Step in c-myc mRNA Degradation

1990 • 100 citations

Postinduction Turnoff of Beta-Interferon Gene Expression

1990 • 96 citations

Regulation of human histone gene expression during the HeLa cell cycle requires protein synthesis.

1984 • 91 citations

The C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites.

1988 • 86 citations

Autogenous Regulation of Histone mRNA Decay by Histone Proteins in a Cell-Free System

1987 • 82 citations

Messenger RNA turnover in eukaryotic cells.

1988 • 74 citations

A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA

1989 • 72 citations

Post-transcriptional regulation of the human liver/bone/kidney alkaline phosphatase gene

1991 • 60 citations

The Structure of the Genome

1984 • 52 citations

Sequence determinants of c-myc mRNA turn-over: influence of 3' and 5' non-coding regions.

1988 • 37 citations

Construction and characterization of SV40 recombinants with beta-globin cDNA substitutions in their early regions.

1981 • 8 citations