Regulation of hormone-sensitive calcium influx by the adenylyl cyclase system in renal epithelial cells.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

The GTPase superfamily: a conserved switch for diverse cell functions

1990 • 2,330 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Diversity of G Proteins in Signal Transduction

1991 • 1,990 citations

Calcium Channels, Stores, and Oscillations

1990 • 1,208 citations

Regulation of Gene Expression in Hippocampal Neurons by Distinct Calcium Signaling Pathways

1993 • 1,165 citations

Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits

1991 • 1,076 citations

G Proteins: A Family of Signal Transducers

1986 • 975 citations

K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

1987 • 947 citations

Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx

1993 • 892 citations

Roles of G protein subunits in transmembrane signalling

1988 • 794 citations

Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium.

1987 • 751 citations

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

1988 • 669 citations

Isolation and characterization of the c-fos(rat) cDNA and analysis of post-translational modification in vitro.

1987 • 630 citations

Hormonal stimulation of adenylyl cyclase through Gi-protein βγ subunits

1992 • 623 citations

A G Protein Directly Regulates Mammalian Cardiac Calcium Channels

1987 • 551 citations

An M2 Muscarinic Receptor Subtype Coupled to Both Adenylyl Cyclase and Phosphoinositide Turnover

1987 • 398 citations

Adenylyl cyclases

1992 • 397 citations

Depletion of InsP3 stores activates a Ca2+ and K+ current by means of a phosphatase and a diffusible messenger

1993 • 363 citations

Cloning and expression of a widely distributed (type IV) adenylyl cyclase.

1991 • 363 citations

The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and guanine nucleotide-dependent hormonal inhibition.

1984 • 345 citations

Signal sorting and amplification through G protein-coupled receptors

1989 • 338 citations

Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis.

1988 • 311 citations

Molecular cloning and characterization of a Ca2+/calmodulin-insensitive adenylyl cyclase from rat brain.

1991 • 286 citations

Gz, a guanine nucleotide-binding protein with unique biochemical properties.

1990 • 282 citations

Direct G protein gating of ion channels

1988 • 258 citations

G _z -Mediated Hormonal Inhibition of Cyclic AMP accumulation

1992 • 258 citations

Inhibition of intracellular cAMP-dependent protein kinase using mutant genes of the regulatory type I subunit.

1987 • 248 citations

Synthesis in Escherichia coli of GTPase-deficient mutants of Gsα

1989 • 247 citations

Mutant α subunits of Gi2 inhibit cyclic AMP accumulation

1991 • 224 citations

Mutations in the GTP-binding site of GSα alter stimulation of adenylyl cyclase

1989 • 209 citations

Purification and characterization of Go alpha and three types of Gi alpha after expression in Escherichia coli.

1990 • 208 citations

Cloning and characterization of a sixth adenylyl cyclase isoform: types V and VI constitute a subgroup within the mammalian adenylyl cyclase family.

1992 • 201 citations

Two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclases.

1992 • 175 citations

Signal transduction by G proteins

1990 • 159 citations

Cyclic GMP modulates depletion-activated Ca2+ entry in pancreatic acinar cells

1993 • 130 citations

Transduction of receptor signal into modulation of effector activity by G proteins: the first 20 years or so …

1990 • 116 citations

Glucagon stimulates the cardiac Ca2+ current by activation of adenylyl cyclase and inhibition of phosphodiesterase

1990 • 114 citations

Activating and inactivating mutations of the alpha subunit of Gi2 protein have opposite effects on proliferation of NIH 3T3 cells.

1991 • 110 citations

c-fos and c-jun are induced by muscarinic receptor activation of protein kinase C but are differentially regulated by intracellular calcium.

1991 • 109 citations

The route of Ca2+ entry during reloading of the intracellular Ca2+ pool in pancreatic acini.

1990 • 104 citations

Distinct guanine nucleotide binding and release properties of the three Gi proteins.

1990 • 75 citations

Lowered responsiveness of the catalyst of adenylyl cyclase to stimulation by GS in heterologous desensitization: a role for adenosine 3',5'-monophosphate-dependent phosphorylation.

1992 • 74 citations

Calcium Channels, Stores, And Oscillations

1990 • 65 citations

GTPase-deficient G alpha i2 oncogene gip2 inhibits adenylylcyclase and attenuates receptor-stimulated phospholipase A2 activity

1991 • 59 citations

G Proteins: A Family of Signal Transducers

1986 • 54 citations

Signal Transduction by G Proteins

2010 • 43 citations

Bradykinin increases cytosolic free [Ca2+] in proximal tubule cells

1988 • 22 citations

G proteins in aortic endothelial cells and bradykinin-induced formation of nitric oxide

1993 • 19 citations