Wnt/β-Catenin and Fgf Signaling Control Collective Cell Migration by Restricting Chemokine Receptor Expression

Lessons from Hereditary Colorectal Cancer

1996 • 4,900 citations

Wnt signalling in stem cells and cancer

2005 • 3,593 citations

Wnt signaling and cancer

2000 • 3,215 citations

Collective cell migration in morphogenesis, regeneration and cancer

2009 • 2,503 citations

Binding of GSK3β to the APC-β-Catenin Complex and Regulation of Complex Assembly

1996 • 1,382 citations

Wnt Signaling in Oncogenesis and Embryogenesis--a Look Outside the Nucleus

2000 • 1,253 citations

Structures of the Tyrosine Kinase Domain of Fibroblast Growth Factor Receptor in Complex with Inhibitors

1997 • 1,098 citations

Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

2007 • 970 citations

Function and biological roles of the Dickkopf family of Wnt modulators

2006 • 960 citations

Self-Renewal and Cancer of the Gut: Two Sides of a Coin

2005 • 678 citations

Prespecification and plasticity: shifting mechanisms of cell migration

2004 • 658 citations

Control of Chemokine-Guided Cell Migration by Ligand Sequestration

2008 • 589 citations

Parallels between tissue repair and embryo morphogenesis

2004 • 554 citations

Distinct Wnt signaling pathways have opposing roles in appendage regeneration

2006 • 522 citations

Chemokine Signaling Mediates Self-Organizing Tissue Migration in the Zebrafish Lateral Line

2006 • 497 citations

Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3β phosphorylation

2001 • 435 citations

Collective cell migration in morphogenesis and cancer

2004 • 432 citations

The Wnt/β-catenin pathway regulates cardiac valve formation

2003 • 389 citations

Chemokine ReceptorCXCR4Expression in Colorectal Cancer Patients Increases the Risk for Recurrence and for Poor Survival

2005 • 372 citations

The role of fibroblast growth factors and their receptors in prostate cancer

2004 • 335 citations

Fgf signaling instructs position-dependent growth rate during zebrafish fin regeneration

2005 • 324 citations

Wild-type but not mutant APC associates with the microtubule cytoskeleton.

1994 • 319 citations

Collective cell movement in primary melanoma explants: plasticity of cell-cell interaction, beta1-integrin function, and migration strategies.

2002 • 314 citations

A GFP-based genetic screen reveals mutations that disrupt the architecture of the zebrafish retinotectal projection

2005 • 308 citations

Molecular basis of cell migration in the fish lateral line: Role of the chemokine receptor CXCR4 and of its ligand, SDF1

2002 • 306 citations

Identification of Sef, a novel modulator of FGF signalling

2002 • 306 citations

Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling

2002 • 303 citations

The Chemokine SDF1a Coordinates Tissue Migration through the Spatially Restricted Activation of Cxcr7 and Cxcr4b

2007 • 302 citations

Mutations affecting development of the zebrafish inner ear and lateral line

1996 • 301 citations

Essential role of non-canonical Wnt signalling in neural crest migration

2005 • 300 citations

FGF-20 and DKK1 are transcriptional targets of β-catenin and FGF-20 is implicated in cancer and development

2004 • 292 citations

Control of cell migration in the development of the posterior lateral line: antagonistic interactions between the chemokine receptors CXCR4 and CXCR7/RDC1

2007 • 290 citations

Anatomy of the posterior lateral line system in young larvae of the zebrafish

1985 • 289 citations

Reiterated Wnt signaling during zebrafish neural crest development

2004 • 261 citations

Development of the zebrafish lateral line

2004 • 256 citations

Zebrafish pea3 and erm are general targets of FGF8 signaling

2001 • 249 citations

Experiments on the development of the cranial ganglia and the lateral line sense organs in Amblystoma punctatum

1922 • 248 citations

The subcellular destinations of apc proteins

2002 • 245 citations

Migration of coordinated cell clusters in mesenchymal and epithelial cancer explants in vitro.

1995 • 239 citations

A Gene Expression Screen in Zebrafish Embryogenesis

2001 • 227 citations

Tight transcriptional control of the ETS domain factors Erm and Pea3 by Fgf signaling during early zebrafish development

2001 • 225 citations

sprouty4acts in vivo as a feedback-induced antagonist of FGF signaling in zebrafish

2001 • 215 citations

Dynamic Fgf signaling couples morphogenesis and migration in the zebrafish lateral line primordium

2008 • 210 citations

The limb identity geneTbx5promotes limb initiation by interacting withWnt2bandFgf10

2002 • 197 citations

Imaging macrophage chemotaxis in vivo: Studies of microtubule function in zebrafish wound inflammation

2006 • 188 citations

EGFL7 regulates the collective migration of endothelial cells by restricting their spatial distribution

2007 • 186 citations

Zebrafishatoh1genes: classic proneural activity in the inner ear and regulation by Fgf and Notch

2006 • 178 citations

Analysis of the Signaling Activities of Localization Mutants of β-Catenin during Axis Specification in Xenopus

1997 • 177 citations

Regional cell movement and tissue patterning in the zebrafish embryo revealed by fate mapping with caged fluorescein

1997 • 176 citations

Expression of functional CXCR4 chemokine receptors on human colonic epithelial cells

1999 • 176 citations

FGF-Dependent Mechanosensory Organ Patterning in Zebrafish

2008 • 175 citations

The zebrafish eya1 gene and its expression pattern during embryogenesis

1999 • 168 citations

Pattern formation in the lateral line of zebrafish

2001 • 166 citations

Twotcf3genes cooperate to pattern the zebrafish brain

2003 • 145 citations

Expression of proneural and neurogenic genes in the zebrafish lateral line primordium correlates with selection of hair cell fate in neuromasts

2001 • 145 citations

Collective guidance of collective cell migration

2007 • 126 citations

Gastrulation in zebrafish — all just about adhesion?

2006 • 126 citations

A role for MKP3 in axial patterning of the zebrafish embryo

2004 • 123 citations

Lack of Adenomatous Polyposis Coli Protein Correlates with a Decrease in Cell Migration and Overall Changes in Microtubule Stability

2006 • 121 citations

Chemokine signaling regulates sensory cell migration in zebrafish

2004 • 114 citations

Electroreceptors and Mechanosensory Lateral Line Organs Arise from Single Placodes in Axolotls

1995 • 90 citations

Dissecting interactions between EB1, microtubules and APC in cortical clusters at the plasma membrane

2002 • 85 citations

Retinoic acid is required for endodermal pouch morphogenesis and not for pharyngeal endoderm specification

2006 • 85 citations

Expression of the Ets transcription factors erm and pea3 in early zebrafish development

1999 • 67 citations

The social lives of migrating cells in Drosophila

2006 • 59 citations

FoxA3 and goosecoid promote anterior neural fate through inhibition of Wnt8a activity before the onset of gastrulation

2005 • 51 citations

Activation of β-catenin Signaling Pathways by Classical G-Protein-Coupled Receptors: Mechanisms and Consequences in Cycling and Non-cycling Cells

2006 • 46 citations

Cell proliferation in the developing lateral line system of zebrafish embryos

2005 • 44 citations

Mutation of the atrophin2 gene in the zebrafish disrupts signaling by fibroblast growth factor during development of the inner ear

2006 • 28 citations

Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal regulation

2005 • 18 citations