Collective cell migration in morphogenesis and cancer

Epithelial–mesenchymal transitions in tumour progression

2002 • 6,431 citations

Cell Migration: A Physically Integrated Molecular Process

1996 • 3,909 citations

Tumour-cell invasion and migration: diversity and escape mechanisms

2003 • 3,069 citations

Rho GTPases Control Polarity, Protrusion, and Adhesion during Cell Movement

1999 • 1,452 citations

Malignant Melanoma

1979 • 1,323 citations

Targeted Deficiency or Cytosolic Truncation of the VE-cadherin Gene in Mice Impairs VEGF-Mediated Endothelial Survival and Angiogenesis

1999 • 1,291 citations

The Stromal Proteinase MMP3/Stromelysin-1 Promotes Mammary Carcinogenesis

1999 • 916 citations

Shaping the Vertebrate Body Plan by Polarized Embryonic Cell Movements

2002 • 718 citations

Matrix Metalloproteinases Regulate Neovascularization by Acting as Pericellular Fibrinolysins

1998 • 716 citations

Prespecification and plasticity: shifting mechanisms of cell migration

2004 • 658 citations

Building epithelial architecture: insights from three-dimensional culture models

2002 • 584 citations

Forces for Morphogenesis Investigated with Laser Microsurgery and Quantitative Modeling

2003 • 506 citations

Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors

1991 • 491 citations

N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells.

2001 • 480 citations

Tensional forces in fibrillar extracellular matrices control directional capillary sprouting

1999 • 446 citations

Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases

2003 • 419 citations

The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis

1973 • 406 citations

The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells

2001 • 373 citations

Novel function for beta 1 integrins in keratinocyte cell-cell interactions.

1990 • 338 citations

DE-Cadherin Is Required for Intercellular Motility during Drosophila Oogenesis

1999 • 330 citations

slow border cells, a locus required for a developmentally regulated cell migration during oogenesis, encodes Drosophila CEBP

1992 • 326 citations

Collective cell movement in primary melanoma explants: plasticity of cell-cell interaction, beta1-integrin function, and migration strategies.

2002 • 314 citations

A model for individual and collective cell movement in Dictyostelium discoideum

2000 • 276 citations

A crucial role of β1 integrins for keratinocyte migration in vitro and during cutaneous wound repair

2002 • 266 citations

Neural precursor cell chain migration and division are regulated through different β1 integrins

1998 • 265 citations

Migration of coordinated cell clusters in mesenchymal and epithelial cancer explants in vitro.

1995 • 239 citations

Epithelial polarity and tubulogenesis in vitro

2003 • 238 citations

VE-Cadherin Mediates Endothelial Cell Capillary Tube Formation in Fibrin and Collagen Gels1

1998 • 216 citations

Matrix Metalloproteinases (MMPs) Regulate Fibrin-invasive Activity via MT1-MMP–dependent and –independent Processes

2002 • 215 citations

Integrin-ECM Interactions Regulate Cadherin-Dependent Cell Adhesion and Are Required for Convergent Extension in Xenopus

2003 • 209 citations

Activated Leukocyte Cell Adhesion Molecule/CD166, a Marker of Tumor Progression in Primary Malignant Melanoma of the Skin

2000 • 208 citations

Malignant Melanoma

1981 • 202 citations

Cadherin repertoire determines partner-specific gap junctional communication during melanoma progression

2000 • 189 citations

Regulation of Endothelial Cell Morphogenesis by Integrins, Mechanical Forces, and Matrix Guidance Pathways

1995 • 182 citations

A Cluster of Noninvoluting Endocytic Cells at the Margin of the Zebrafish Blastoderm Marks the Site of Embryonic Shield Formation

1996 • 177 citations

Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulation

2003 • 165 citations

In Vivo Migration of Transplanted Myoblasts Requires Matrix Metalloproteinase Activity

2000 • 160 citations

Plasmin-Sensitive Dibasic Sequences in the Third Fibronectin-like Domain of L1–Cell Adhesion Molecule (Cam) Facilitate Homomultimerization and Concomitant Integrin Recruitment

2000 • 150 citations

Movements of Epithelial Cell Sheets In Vitro

1966 • 148 citations

α5β1 integrin mediates strong tissue cohesion

2002 • 145 citations

Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix

2003 • 143 citations

Laminin and β1 Integrins Are Crucial for Normal Mammary Gland Development in the Mouse

1999 • 136 citations

Front-cell-specific expression of membrane-type 1 matrix metalloproteinase and gelatinase A during cohort migration of colon carcinoma cells induced by hepatocyte growth factor/scatter factor.

2000 • 133 citations

Migration patterns of the precardiac mesoderm in the early chick embryo

1963 • 132 citations

Angiogenesis in Collagen I Requires α2β1 Ligation of a GFP*GER Sequence and Possibly p38 MAPK Activation and Focal Adhesion Disassembly

2003 • 130 citations

Isolation of prostate-derived single cells and cell clusters from human peripheral blood.

1996 • 128 citations

E-cadherin/catenin complex in benign and malignant melanocytic lesions

1998 • 119 citations

Zur Regeneration der Gewebe

1891 • 103 citations

Rapid cellular translocation is related to close contacts formed between various cultured cells and their substrata

1982 • 103 citations

Expression of desmosomal proteins in squamous cell carcinomas of the skin

2003 • 101 citations

Cohort migration of carcinoma cells: differentiated colorectal carcinoma cells move as coherent cell clusters or sheets.

1999 • 98 citations

α1 and α2 Integrins Mediate Invasive Activity of Mouse Mammary Carcinoma Cells through Regulation of Stromelysin-1 Expression

1999 • 94 citations

Expression of β‐catenin in normal breast tissue and breast carcinoma: a comparative study with epithelial cadherin and α‐catenin

1996 • 91 citations

Role of E-cadherin in the response of tumor cell aggregates to lymphatic, venous and arterial flow: measurement of cell-cell adhesion strength

1995 • 84 citations

Measurement of the Ability of Cells to Infiltrate Normal Tissues in vitro

1974 • 81 citations

On the convergent cell movements of gastrulation in Fundulus

1992 • 81 citations

The movement of cell clusters in vitro. morphology and directionality

1981 • 75 citations

E-cadherin is a ligand for integrin α2β1

2002 • 62 citations

Connexin Transfection Induces Invasive Properties in HeLa Cells

1998 • 59 citations

Identification of mutations that cause cell migration defects in mosaic clones

1999 • 56 citations

Cadherins as Predictive Markers of Nodal Metastasis in Breast Cancer

2001 • 55 citations

Reconstructing Leukocyte Migration in 3D Extracellular Matrix by Time-Lapse Videomicroscopy and Computer-Assisted Tracking

2003 • 55 citations

Hepatocyte growth factor/scatter factor induces not only scattering but also cohort migration of human colorectal‐adenocarcinoma cells

1998 • 49 citations

β-Catenin expression pattern in primary oesophageal squamous cell carcinoma. Relationship with clinicopathologic features and clinical outcome

2000 • 49 citations

pS2 transfection of murine adenocarcinoma cell line 410.4 enhances dispersed growth pattern in a 3-D collagen gel

1996 • 48 citations

The midblastula transition, the YSL transition and the onset of gastrulation in Fundulus

1992 • 47 citations

Activation of β1 Integrins Induces Cell–Cell Adhesion

2001 • 46 citations

Hepatocyte growth factor/scatter factor induces not only scattering but also cohort migration of human colorectal-adenocarcinoma cells

1998 • 43 citations

Ueber bewegliche thierische Zellen

1863 • 34 citations

Variability of cell size in primary and metastatic human breast carcinoma.

1986 • 31 citations

Ultrastructural study of TPA-induced cell motility: human well-differentiated rectal adenocarcinoma cells move as coherent sheets via localized modulation of cell-cell adhesion

1995 • 27 citations

The closing of wounds in the larval necturus

1907 • 18 citations

Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors

1992 • 18 citations

Tumor Cell Invasion and Gap Junctional Communication

1990 • 15 citations

Developmental regulation of cell migration

1999 • 15 citations

Patterns of cell movement in early organ primordia of the chick embryo

1990 • 13 citations