DIP (mDia interacting protein) is a key molecule regulating Rho and Rac in a Src-dependent manner

Rho GTPases in cell biology

2002 • 4,662 citations

Integrins and Signal Transduction Pathways: the Road Taken

1995 • 3,002 citations

Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)

1996 • 1,964 citations

Rho GTPases and their effector proteins

2000 • 1,941 citations

Rho GTPases Control Polarity, Protrusion, and Adhesion during Cell Movement

1999 • 1,452 citations

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.

1996 • 1,045 citations

Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

1999 • 884 citations

The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.

1996 • 872 citations

Sensing the environment: a historical perspective on integrin signal transduction

2002 • 855 citations

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

1997 • 819 citations

Rho GTPases and their effector proteins

2000 • 461 citations

RhoA Inactivation by p190RhoGAP Regulates Cell Spreading and Migration by Promoting Membrane Protrusion and Polarity

2001 • 431 citations

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

2000 • 429 citations

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

1998 • 426 citations

The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases.

1995 • 410 citations

Diaphanous-Related Formins Bridge Rho GTPase and Src Tyrosine Kinase Signaling

2000 • 379 citations

Integrin regulation of growth factor receptors

2002 • 295 citations

c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation.

1995 • 256 citations

p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation

2001 • 245 citations

Inhibition of PMA-induced, LFA-1-dependent lymphocyte aggregation by ADP ribosylation of the small molecular weight GTP binding protein, rho.

1993 • 223 citations

RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase

2003 • 223 citations

ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts

2002 • 212 citations

Microtubules meet substrate adhesions to arrange cell polarity

2003 • 212 citations

p160ROCK mediates RhoA activation of Na-H exchange

1998 • 204 citations

A role for LIM kinase in cancer invasion

2003 • 204 citations

Vav Family Proteins Couple to Diverse Cell Surface Receptors

2000 • 148 citations

Small GTPase RhoG Is a Key Regulator for Neurite Outgrowth in PC12 Cells

2000 • 138 citations

Mechanism of Epidermal Growth Factor Regulation of Vav2, a Guanine Nucleotide Exchange Factor for Rac

2003 • 114 citations

Vav2 is required for cell spreading

2001 • 100 citations

mDia-interacting Protein Acts Downstream of Rho-mDia and Modifies Src Activation and Stress Fiber Formation

2001 • 85 citations

ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts

2003 • 32 citations

RhoA Inactivation by p190RhoGAP Regulates Cell Spreading and Migration by Promoting Membrane Protrusion and Polarity

2001 • 19 citations

Vav Family Proteins Couple to Diverse Cell Surface Receptors

2000 • 12 citations