Molecular genetic studies of schizophrenia

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

1993 • 8,888 citations

The Future of Genetic Studies of Complex Human Diseases

1996 • 5,355 citations

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1991 • 4,533 citations

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1995 • 3,985 citations

Genetic Dissection of Complex Traits

1994 • 3,497 citations

Molecular basis of myotonic dystrophy: Expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member

1992 • 2,719 citations

Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus

1995 • 2,548 citations

Large-Scale Identification, Mapping, and Genotyping of Single-Nucleotide Polymorphisms in the Human Genome

1998 • 2,163 citations

Variations on a Theme: Cataloging Human DNA Sequence Variation

1997 • 1,064 citations

The Genetic Basis of Complex Human Behaviors

1994 • 1,028 citations

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

1995 • 749 citations

The Roscommon Family Study

1993 • 712 citations

Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21

1998 • 542 citations

A Simple Genetic Basis for a Complex Psychological Trait in Laboratory Mice

1995 • 447 citations

A Meta-analysis of the Association of the Deletion Allele of the Angiotensin-Converting Enzyme Gene With Myocardial Infarction

1996 • 425 citations

Genome scan of European-American schizophrenia pedigrees: Results of the NIMH genetics initiative and millennium consortium

1998 • 278 citations

A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter

1998 • 254 citations

The genetic basis for schizophrenia

1973 • 247 citations

A combined analysis of D22S278 marker alleles in affected sib-pairs: Support for a susceptibility locus for schizophrenia at chromosome 22q12

1996 • 232 citations

Affected-sib-pair interval mapping and exclusion for complex genetic traits: Sampling considerations

1996 • 225 citations

Association Mapping of Disease Loci, by Use of a Pooled DNA Genomic Screen

1997 • 219 citations

Comparison of statistics for candidate-gene association studies using cases and parents.

1994 • 203 citations

Support for a possible schizophrenia vulnerability locus in region 5q22–31 in Irish families

1997 • 192 citations

Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strains

1994 • 181 citations

Evidence for anticipation in schizophrenia.

1994 • 181 citations

Relationship between homozygosity at the dopamine D3 receptor gene and schizophrenia

1994 • 179 citations

The Roscommon Family Study

1993 • 168 citations

A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia

1998 • 167 citations

Evidence suggestive of a locus on chromosome 5q31 contributing to susceptibility for schizophrenia in German and Israeli families by multipoint affected sib-pair linkage analysis

1997 • 157 citations

A schizophrenia locus may be located in region 10p15-p11

1998 • 148 citations

Support for a Chromosome 18p Locus Conferring Susceptibility to Functional Psychoses in Families with Schizophrenia, by Association and Linkage Analysis

1998 • 145 citations

Genes, Experience, and Chance in Schizophrenia--Positioning for the 21st Century

1997 • 128 citations

A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping or DNA sequencing. V. Analysis of case/control sampling designs: Alzheimer's disease and the apoprotein E locus.

1995 • 124 citations

A Simple Method for Analyzing Microsatellite Allele Image Patterns Generated from DNA Pools and Its Application to Allelic Association Studies

1998 • 123 citations

CAG repeat expansions and schizophrenia: association with disease in females and with early age-at-onset

1995 • 123 citations

Mathematical limits of multilocus models: the genetic transmission of bipolar disorder.

1995 • 119 citations

NCAM-180 knockout mice display increased lateral ventricle size and reduced prepulse inhibition of startle

1998 • 109 citations

A Novel, Heritable, Expanding CTG Repeat in an Intron of the SEF2-1 Gene on Chromosome 18q21.1

1997 • 109 citations

Association studies in psychiatric genetics

1997 • 105 citations

A Turning Point in Schizophrenia Genetics

1997 • 101 citations

Imprinting and Anticipation

1994 • 93 citations

Evidence by allelic association-dependent methods for a type 1 diabetes polygene (IDDM6) on chromosome 18q21

1997 • 93 citations

A major quantitative trait locus influences hyperactivity in the WKHA rat

1996 • 86 citations

The maddening hunt for madness genes

1997 • 80 citations

Survey of cases of familial mental illness

1991 • 77 citations

Efficient strategies for genome scanning using maximum-likelihood affected-sib-pair analysis.

1997 • 58 citations

Further evidence for anticipation in schizophrenia

1995 • 55 citations

Multiple DNA variant association analysis: application to the insulin gene region in type I diabetes.

1994 • 54 citations

What Is Significant in Whole-Genome Linkage Disequilibrium Studies?

1997 • 51 citations

A Novel Long and Unstable CAG/CTG Trinucleotide Repeat on Chromosome 17q

1998 • 44 citations

The behavioural phenotype in velo‐cardio‐facial syndrome

2004 • 43 citations

Do animal models have a place in the genetic analysis of quantitative human behavioural traits?

1996 • 42 citations

The Molecular Genetics of Schizophrenia

1996 • 28 citations

Anticipation in multiplex schizophrenia pedigrees

1996 • 23 citations

Molecular genetic studies of schizophrenia.

1996 • 22 citations

Deleted Work

1955 • 0 citations