Ezrin-Radixin-Moesin-binding Phosphoprotein-50/Na+/H+ Exchanger Regulatory Factor (EBP50/NHERF) Blocks U50,488H-induced Down-regulation of the Human κ Opioid Receptor by Enhancing Its Recycling Rate

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Psychotomimesis Mediated by κ Opiate Receptors

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U-50,488: a selective and structurally novel non-Mu (kappa) opioid agonist.

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The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange

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Identification of EBP50: A PDZ-containing Phosphoprotein that Associates with Members of the Ezrin-Radixin-Moesin Family

1997 • 582 citations

Association of β-Arrestin with G Protein-coupled Receptors during Clathrin-mediated Endocytosis Dictates the Profile of Receptor Resensitization

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PDZ Proteins Organize Synaptic Signaling Pathways

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A C-terminal motif found in the β ₂ -adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na ⁺ /H ⁺ exchanger regulatory factor family of PDZ proteins

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Ezrin: A protein requiring conformational activation to link microfilaments to the plasma membrane in the assembly of cell surface structures

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PDZ domains bind carboxy-terminal sequences of target proteins

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Role of endocytosis in mediating downregulation of G-protein-coupled receptors

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Molecular biology and pharmacology of cloned opioid receptors ¹

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U50,488H-induced Internalization of the Human κ Opioid Receptor Involves a β-Arrestin- and Dynamin-dependent Mechanism

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Down-regulation of opiate receptor in neuroblastoma x glioma NG108-15 hybrid cells. Chloroquine promotes accumulation of tritiated enkephalin in the lysosomes.

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Binding of the β2 Adrenergic Receptor toN-Ethylmaleimide-sensitive Factor Regulates Receptor Recycling

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PDZ-dependent Activation of Nitric-oxide Synthases by the Serotonin 2B Receptor

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Thr353, Located within the COOH-terminal Tail of the ´ Opiate Receptor, Is Involved in Receptor Down-regulation

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Cloning of a human κ opioid receptor from the brain

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Mechanisms of Agonist-Induced Down-Regulation of the Human κ-Opioid Receptor: Internalization Is Required for Down-Regulation

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Identification of Two Distinct Structural Motifs That, When Added to the C-Terminal Tail of the Rat LH Receptor, Redirect the Internalized Hormone-Receptor Complex from a Degradation to a Recycling Pathway

2001 • 52 citations

Molecular Basis of Differences in (−)(trans)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidiny)-cyclohexyl]benzeneacetamide-Induced Desensitization and Phosphorylation between Human and Rat κ-Opioid Receptors Expressed in Chinese Hamster Ovary Cells

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Identification and characterization of opioid and somatostatin binding sites in the opossum kidney (OK) cell line and their effect on growth.

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Identification of Serine 356 and Serine 363 as the Amino Acids Involved in Etorphine-induced Down-regulation of the μ-Opioid Receptor

1998 • 42 citations

Agonist-induced desensitization and down-regulation of the human kappa opioid receptor expressed in Chinese hamster ovary cells.

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Identification and characterization of opioid and somatostatin binding sites in the opossum kidney (OK) cell line and their effect on growth

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The Conserved Cysteine 7.38 Residue Is Differentially Accessible in the Binding-Site Crevices of the μ, δ, and κ Opioid Receptors

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