Regulation and Targeting of Recombination in Extrachromosomal Substrates Carrying Immunoglobulin Switch Region Sequences

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

The Role of Helper T Cell Products in Mouse B Cell Differentiation and Isotype Regulation

1988 • 764 citations

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

1985 • 710 citations

On the formation of spontaneous deletions: The importance of short sequence homologies in the generation of large deletions

1982 • 690 citations

The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

1992 • 684 citations

Development of the Primary Antibody Repertoire

1987 • 629 citations

Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.

1992 • 536 citations

Integration host factor: A protein for all reasons

1988 • 501 citations

V(D)J recombination: a functional definition of the joining signals.

1989 • 467 citations

Shutdown of Class Switch Recombination by Deletion of a Switch Region Control Element

1993 • 340 citations

Recombination-stimulating sequences in yeast ribosomal DNA correspond to sequences regulating transcription by RNA polymerase I

1987 • 317 citations

Mechanisms of nonhomologous recombination in mammalian cells.

1985 • 314 citations

DNA sequences at immunoglobulin switch region recombination sites

1993 • 275 citations

Functional replacement of a protein-induced bend in a DNA recombination site

1989 • 259 citations

A novel B-cell lineage-specific transcription factor present at early but not late stages of differentiation.

1990 • 244 citations

Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line.

1991 • 240 citations

Immunoglobulin Class Switching: Molecular and Cellular Analysis

1990 • 224 citations

A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon.

1993 • 206 citations

MECHANISM AND DEVELOPMENTAL PROGRAM OF IMMUNOGLOBULIN GENE REARRANGEMENT IN MAMMALS

1989 • 144 citations

Structure and expression of germ line immunoglobulin gamma 2b transcripts.

1988 • 136 citations

Transcription factors are required for the meiotic recombination hotspot at the HIS4 locus in Saccharomyces cerevisiae.

1993 • 129 citations

Recombination between similar but not identical DNA sequences during yeast transformation occurs within short stretches of identity

1992 • 127 citations

Functional analysis of the murine IgH enhancer: evidence for negative control of cell-type specificity

1986 • 123 citations

Interleukin 5 (IL-5) provides a signal that is required in addition to IL-4 for isotype switching to immunoglobulin (Ig) G1 and IgE.

1992 • 108 citations

A poly(dA.dT) tract is a component of the recombination initiation site at the ARG4 locus in Saccharomyces cerevisiae.

1991 • 106 citations

Recombination between short direct repeats in a RecA host

1982 • 90 citations

Identification and Characterization of Two Functional Domains within the Murine Heavy-Chain Enhancer

1988 • 81 citations

Transcriptional regulatory elements stimulate recombination in extrachromosomal substrates carrying immunoglobulin switch-region sequences.

1992 • 74 citations

A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation.

1989 • 65 citations

Complete nucleotide sequence of the murine gamma 3 switch region and analysis of switch recombination sites in two gamma 3-expressing hybridomas.

1985 • 65 citations

LR1, a lipopolysaccharide-responsive factor with binding sites in the immunoglobulin switch regions and heavy-chain enhancer.

1991 • 65 citations

A nuclear DNA-binding protein expressed during early stages of B cell differentiation interacts with diverse segments within and 3' of the Ig H chain gene cluster.

1992 • 64 citations

The Immunoglobulin Heavy-Chain Enhancer Functions as the Promoter for Iμ Sterile Transcription

1990 • 61 citations

Immunoglobulin heavy chain switch region recombination within a retroviral vector in murine pre-B cells.

1987 • 59 citations

Switch recombination breakpoints are strictly correlated with DNA recognition motifs for immunoglobulin S gamma 3 DNA-binding proteins.

1992 • 49 citations

Detection of an immunoglobulin switch region-specific DNA-binding protein in mitogen-stimulated mouse splenic B cells.

1990 • 43 citations

Illegitimate recombination in an Escherichia coli plasmid: modulation by DNA damage and a new bacterial gene

1988 • 43 citations

V(D)J recombination on minichromosomes is not affected by transcription.

1992 • 41 citations

A rapid method for determining the molecular weight of a protein bound to nucleic acid in a mobility shift assay

1992 • 31 citations

Purification and properties of LR1, an inducible DNA binding protein from mammalian B lymphocytes

1993 • 22 citations

Stimulation of κ Light-Chain Gene Rearrangement by the Immunoglobulin μ Heavy Chain in a Pre-B-Cell Line

1993 • 18 citations

An examination of the effects of double-strand breaks on extrachromosomal recombination in mammalian cells.

1992 • 10 citations

Deleted Work

1955 • 0 citations