Mechanisms of nonhomologous recombination in mammalian cells.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Hypervariable ‘minisatellite’ regions in human DNA

1985 • 3,789 citations

The double-strand-break repair model for recombination

1983 • 2,468 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1984 • 1,239 citations

Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions.

1982 • 755 citations

Mobile genetic elements

1997 • 630 citations

Insertion of N regions into heavy-chain genes is correlated with expression of terminal deoxytransferase in B cells

1984 • 540 citations

Mobile Genetic Elements

1983 • 482 citations

Model for Homologous Recombination During Transfer of DNA into Mouse L Cells: Role for DNA Ends in the Recombination Process

1984 • 457 citations

Mouse T cell antigen receptor: Structure and organization of constant and joining gene segments encoding the β polypeptide

1984 • 407 citations

High mutation frequency in DNA transfected into mammalian cells.

1983 • 338 citations

Model for homologous recombination during transfer of DNA into mouse L cells: role for DNA ends in the recombination process.

1984 • 227 citations

An SV40 “enhancer trap” incorporates exogenous enhancers or generates enhancers from its own sequences

1984 • 223 citations

Mutational analysis of simian virus 40 T antigen: isolation and characterization of mutants with deletions in the T-antigen gene.

1983 • 210 citations

Rearrangement and mutagenesis of a shuttle vector plasmid after passage in mammalian cells.

1983 • 207 citations

Somatic Cells Efficiently Join Unrelated DNA Segments End-to-End

1982 • 186 citations

Pseudogenes for human small nuclear RNA U3 appear to arise by integration of self-primed reverse transcripts of the RNA into new chromosomal sites

1983 • 178 citations

Recombination in mouse L cells between DNA introduced into cells and homologous chromosomal sequences.

1985 • 165 citations

High-Efficiency Ligation and Recombination of DNA Fragments by Vertebrate Cells

1983 • 148 citations

Relative rates of homologous and nonhomologous recombination in transfected DNA.

1985 • 145 citations

DNA sequence homology and chromosomal deletion at a site of SV40 DNA integration

1982 • 143 citations

Internal sequences are eliminated from genes during macronuclear development in the ciliated protozoan oxytricha nova

1984 • 140 citations

Transfected DNA is mutated in monkey, mouse, and human cells.

1984 • 138 citations

Cold-sensitive regulatory mutants of simian virus 40

1980 • 130 citations

Translocation of the myc cellular oncogene to the immunoglobulin heavy chain locus in murine plasmacytomas is an imprecise reciprocal exchange

1984 • 128 citations

Transcriptionally active DNA region that rearranges frequently in murine lymphoid tumors.

1982 • 126 citations

How damaged is the biologically active subpopulation of transfected DNA?

1984 • 124 citations

Topological requirements for homologous recombination among DNA molecules transfected into mammalian cells.

1985 • 122 citations

Specific DNA rearrangements in synchronously developing nuclei of Tetrahymena.

1984 • 121 citations

An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing

1980 • 121 citations

Homologous and nonhomologous recombination in monkey cells.

1983 • 114 citations

Mutational Analysis of Simian Virus 40 T Antigen: Isolation and Characterization of Mutants with Deletions in the T-Antigen Gene

1983 • 112 citations

Organization of the Epstein-Barr virus DNA molecule. III. Location of the P3HR-1 deletion junction and characterization of the NotI repeat units that form part of the template for an abundant 12-O-tetradecanoylphorbol-13-acetate-induced mRNA transcript

1983 • 104 citations

Spontaneous deletions and duplications of sequences in the genome of cowpox virus.

1984 • 99 citations

Mutagenesis of a shuttle vector plasmid in mammalian cells.

1984 • 94 citations

DNA sequence studies of simian virus 40 chromosomal excision and integration in rat cells

1984 • 93 citations

Somatic cells efficiently join unrelated DNA segments end-to-end.

1982 • 91 citations

On the Mechanism of Recombination Between Adenoviral and Cellular DNAs: The Structure of Junction Sites

1983 • 82 citations

A rapid enzymatic DNA sequencing technique: determination of sequence alterations in early simian virus 40 temperature sensitive and deletion mutants

1980 • 78 citations

Evolutionary variants of simian virus 40: Cellular DNA sequences and sequences at recombinant joints of substituted variants

1978 • 78 citations

How Damaged is the Biologically Active Subpopulation of Transfected DNA?

1984 • 74 citations

Clustered illegitimate recombination events in mammalian cells involving very short sequence homologies

1983 • 72 citations

Topological Requirements for Homologous Recombination Among DNA Molecules Transfected into Mammalian Cells

1985 • 72 citations

Reciprocal chromosome translocation between c-myc and immunoglobulin γ2b genes

1983 • 69 citations

A pattern of partially homologous recombination in mouse L cells.

1984 • 68 citations

Homologous and Nonhomologous Recombination in Monkey Cells

1983 • 68 citations

Transfected DNA Is Mutated in Monkey, Mouse, and Human Cells

1984 • 67 citations

Analysis of Homologous Recombination in Cultured Mammalian Cells

1984 • 61 citations

Differences in Intracellular DNA Ligation After Microinjection and Transfection

1984 • 57 citations

Homologous Recombination with DNA Introduced into Mammalian Cells

1984 • 54 citations

High Spontaneous Mutation Frequency in Shuttle Vector Sequences Recovered from Mammalian Cellular DNA

1984 • 51 citations

Recombination in SV40-infected cells: Viral DNA sequences at sites of circularization of transfecting linear DNA

1981 • 43 citations

Structure of simian virus 40 recombinants that contain both host and viral DNA sequences. I. The structure of variant CVPS/1/P2 (EcoRI res).

1979 • 43 citations

Site-specific excision of integrated polyoma DNA

1984 • 42 citations

Characterization and sequence analysis of a recombination site in the hybrid virus Ad2+ND1

1978 • 39 citations

Recombination in SV40-infected cells: Nucleotide sequences at viral-viral recombinant joints in naturally arising variants

1981 • 39 citations

A viable simian virus 40 variant that carries a newly generated sequence reiteration in place of the normal duplicated enhancer element.

1984 • 38 citations

Structure of simian virus 40 recombinants that contain both host and viral DNA sequences. II. The structure of variant 1103 and its comparison to variant CVPS/1P2 (EcoRI res).

1979 • 38 citations

Interference in SV40 DNA infections: A possible basis for cellular competence

1978 • 34 citations

Differences in intracellular DNA ligation after microinjection and transfection.

1984 • 32 citations

Structure and synthesis of a simian virus 40 super T-antigen

1982 • 30 citations

Genetic analysis of host range mutant viruses suggests an uncoating defect in simian virus 40-resistant monkey cells

1977 • 26 citations

Mutagenesis of a Shuttle Vector Plasmid in Mammalian Cells

1984 • 22 citations

Recombination in simian virus 40-infected cells. Structure of naturally arising variants ev-2114, ev-2102, and ev-1110.

1983 • 21 citations

Nucleotide sequence analysis of the recombinant joints in 16 naturally arising deletion mutants of simian virus 40

1982 • 21 citations

Short direct repeats mediate spontaneous high-frequency deletions in DNA of minute virus of mice.

1984 • 18 citations

Sequence of the junction in adenovirus 2-SV40 hybrids: examples of illegitimate recombination

1982 • 16 citations

Genomic arrangement of an adenovirus-simian virus 40 hybrid virus, Ad2+ND4del

1981 • 14 citations

Short Direct Repeats Mediate Spontaneous High-Frequency Deletions in DNA of Minute Virus of Mice

1984 • 8 citations

Two types of deletion within integrated viral sequences mediate reversion of simian virus 40-transformed mouse cells

1984 • 8 citations