IGF-1 phosphorylates AMPK-α subunit in ATM-dependent and LKB1-independent manner

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

2002 • 4,335 citations

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

2003 • 3,385 citations

ATM and related protein kinases: safeguarding genome integrity

2003 • 2,516 citations

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

2002 • 2,024 citations

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

2004 • 1,710 citations

Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade

2003 • 1,604 citations

LKB1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade

2003 • 1,599 citations

A serine/threonine kinase gene defective in Peutz–Jeghers syndrome

1998 • 1,588 citations

THE AMP-ACTIVATED/SNF1 PROTEIN KINASE SUBFAMILY: Metabolic Sensors of the Eukaryotic Cell?

1998 • 1,446 citations

Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase

1996 • 1,222 citations

5-Aminoimidazole-4-Carboxamide Ribonucleoside. A Specific Method for Activating AMP-Activated Protein Kinase in Intact Cells?

1995 • 1,163 citations

5-Aminoimidazole-4-Carboxamide Ribonucleoside. A Specific Method for Activating AMP-Activated Protein Kinase in Intact Cells?

1995 • 896 citations

The regulation of AMP-activated protein kinase by phosphorylation

2000 • 582 citations

Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases

2003 • 580 citations

AMP-activated protein kinase, super metabolic regulator

2003 • 457 citations

AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the α2 isoform

1998 • 431 citations

Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

2002 • 346 citations

Mammalian AMP-activated protein kinase shares structural and functional homology with the catalytic domain of yeast Snf1 protein kinase.

1994 • 330 citations

Critical roles of AMP-activated protein kinase in constitutive tolerance of cancer cells to nutrient deprivation and tumor formation

2002 • 193 citations

Activation of 5′-AMP-activated Kinase Is Mediated through c-Src and Phosphoinositide 3-Kinase Activity during Hypoxia-Reoxygenation of Bovine Aortic Endothelial Cells

2003 • 166 citations

Signalling through IGF-I and insulin receptors: where is the specificity?

2002 • 163 citations

Identification of a Novel Protein Kinase Mediating Akt Survival Signaling to the ATM Protein

2002 • 152 citations

E2F1 Uses the ATM Signaling Pathway to Induce p53 and Chk2 Phosphorylation and Apoptosis

2004 • 152 citations

Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase

2001 • 129 citations

ARK5 Is a Tumor Invasion-Associated Factor Downstream of Akt Signaling

2004 • 128 citations

New member of the Snf1/AMPK kinase family,Melk, is expressed in the mouse egg and preimplantation embryo

1997 • 115 citations

Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366

2002 • 114 citations

Potential mechanisms and consequences of cardiac triacylglycerol accumulation in insulin-resistant rats

2003 • 107 citations

Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype

1997 • 103 citations

The Plant Isoflavenoid Genistein Activates p53 and Chk2 in an ATM-dependent Manner

2001 • 95 citations

Inhibition of Chk1 by Activated PKB/Akt

2004 • 81 citations

The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX

2003 • 69 citations

Targeting the AMP-Activated Protein Kinase for the Treatment of Type 2 Diabetes

2002 • 68 citations

Calcineurin is required for translational control of protein synthesis in rat pancreatic acini

2004 • 64 citations

Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK

2001 • 64 citations

AMP-activated protein kinase kinase: detection with recombinant AMPK α1 subunit

2002 • 58 citations

Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK

2001 • 52 citations

Determination of the chromosomal site for the human radiosensitive ataxia telangiectasia gene by chromosome transfer

1991 • 17 citations

Role of ATM in Radiation Signal Transduction

2003 • 4 citations