Fuel utilization by cells of the immune system

The Effect of Dietary Supplementation with n—3 Polyunsaturated Fatty Acids on the Synthesis of Interleukin-1 and Tumor Necrosis Factor by Mononuclear Cells

1989 • 1,951 citations

Oral (n-3) Fatty Acid Supplementation Suppresses Cytokine Production and Lymphocyte Proliferation: Comparison between Young and Older Women

1991 • 704 citations

Glutamine metabolism in lymphocytes of the rat

1983 • 442 citations

Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages

1986 • 404 citations

Muscle and Plasma Amino Acids Following Injury Influence of Intercurrent Infection

1980 • 401 citations

Does glutamine contribute to immunosuppression after major burns?

1990 • 360 citations

Mononuclear Phagocytes

2016 • 350 citations

The role of high rates of glycolysis and glutamine utilization in rapidly dividing cells

1985 • 350 citations

Metabolic disorders in severe abdominal sepsis: Glutamine deficiency in skeletal muscle

1982 • 332 citations

Glycolysis, glutaminolysis and cell proliferation

1982 • 305 citations

Uptake and incorporation of saturated and unsaturated fatty acids into macrophage lipids and their effect upon macrophage adhesion and phagocytosis

1990 • 303 citations

Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophages

1987 • 300 citations

Essential fatty acids and immune response

1989 • 265 citations

Plasma amino acid concentrations in the overtraining syndrome

1992 • 240 citations

Incorporation of fatty acids by concanavalin A-stimulated lymphocytes and the effect on fatty acid composition and membrane fluidity

1994 • 233 citations

Metabolism in lymphocytes and its importance in the immune response.

1985 • 228 citations

Maximum activities of some enzymes of glycolysis, the tricarboxylic acid cycle and ketone-body and glutamine utilization pathways in lymphocytes of the rat

1982 • 217 citations

Rates of utilization of glucose, glutamine and oleate and formation of end-products by mouse peritoneal macrophages in culture

1989 • 215 citations

The effect of dietary lipid manipulation on rat lymphocyte subsets and proliferation.

1994 • 205 citations

Glutamine and glucose metabolism during thymocyte proliferation. Pathways of glutamine and glutamate metabolism

1985 • 188 citations

Secretion of lipoprotein lipase by macrophages in culture.

1981 • 173 citations

Glutamine and macrophage function

1992 • 171 citations

Changes in the carbohydrate metabolism of mitogenically stimulated human peripheral lymphocytes

1973 • 168 citations

Aerobic glycolysis and lymphocyte transformation

1978 • 167 citations

Lipoprotein lipase secretion by human monocyte-derived macrophages.

1982 • 166 citations

Effects of Major and Minor Surgery on Plasma Glutamine and Cytokine Levels

1992 • 162 citations

Glutamine and the immune system

1994 • 161 citations

Response of endocytosis to altered fatty acyl composition of macrophage phospholipids.

1977 • 159 citations

The inhibition of T-lymphocyte proliferation by fatty acids is via an eicosanoid-independent mechanism.

1992 • 155 citations

Polyunsaturated fatty acids suppress human peripheral blood lymphocyte proliferation and interleukin-2 production

1992 • 150 citations

Glutamine and glucose metabolism in human peripheral lymphocytes

1988 • 139 citations

Suppression of interleukin 2-dependent human T cell growth in vitro by prostaglandin E (PGE) and their precursor fatty acids. Evidence for a PGE-independent mechanism of inhibition by the fatty acids.

1990 • 139 citations

Very long chain n‐3 and n‐6 polyunsaturated fatty acids inhibit proliferation of human T‐lymphocytes in vitro

1993 • 137 citations

Inhibition of natural killer cell activity by dietary lipids

1994 • 136 citations

Effect of fatty acids on the proliferation of concanavalin a-stimulated rat lymph node lymphocytes

1991 • 117 citations

Changes in the carbohydrate metabolism of mitogenically stimulated human peripheral lymphocytes. 3. Stimulation by tuberculin and allogenic cells.

1973 • 104 citations

Post-operative changes in hepatic, intestinal, splenic and muscle fluxes of amino acids and ammonia in pigs

1992 • 97 citations

Metabolism of glutamine in lymphocytes

1989 • 82 citations

Lipoprotein lipase secretion by human monocytes and rabbit alveolar macrophages in culture.

1982 • 81 citations

Enzyme-induced asparagine and glutamine depletion and immune system function

1983 • 81 citations

Eicosapentaenoic acid inhibits antigen-presenting cell function of murine splenocytes.

1992 • 79 citations

The effect of glutamine concentration on the activity of carbamoyl-phosphate synthase II and on the incorporation of [3H]thymidine into DNA in rat mesenteric lymphocytes stimulated by phytohaemagglutinin

1989 • 78 citations

Phytohaemagglutinin stimulation of human lymphocytes Effect of fatty acids on uridine uptake and phosphogylceride fatty acid profile

1977 • 71 citations

Effect of eicosapentaenoic and docosahexaenoic acid on natural killer cell activity in human peripheral blood lymphocytes

1991 • 67 citations

Glutamine and fatty acid oxidation are the main sources of energy for Kupffer and endothelial cells

1991 • 60 citations

Inhibition of lymphocyte proliferation by free fatty acids. I. Differential effects on mouse B and T lymphocytes.

1984 • 58 citations

Unsaturated fatty acids suppress interleukin‐2 production and transferrin receptor expression by concanavalin A‐stimulated rat Iymphocytes

1992 • 55 citations

Intracellular distribution of some enzymes of the glutamine utilisation pathway in rat lymphocytes

1986 • 54 citations

The effects of fatty acids on lymphocyte functions

1993 • 53 citations

Incorporation of palmitic acid or oleic acid into macrophage membrane lipids exerts differential effects on the function of normal mouse peritoneal macrophages

1984 • 51 citations

Perspectives in Clinical Nutrition

1989 • 51 citations

Metabolism of ketone bodies, oleate and glucose in lymphocytes of the rat

1984 • 50 citations

Triacylglycerol metabolism by lymphocytes and the effect of triacylglycerols on lymphocyte proliferation

1994 • 43 citations

Phosphorylation and activation of hormone‐sensitive lipase in isolated macrophages

1991 • 42 citations

The effect of glutamine on murine splenic leukocyte responses to T and B cell mitogens

1990 • 42 citations

L-Glutaminase: Suppression of Lymphocyte Blastogenic Responses in vitro

1971 • 39 citations

Effect of Fatty Acid Mixtures on Phytohaemagglutinin-Stimulated Lymphocytes of Different Species

1977 • 39 citations

Influence of antioxidant vitamins on fatty acid inhibition of lymphocyte proliferation.

1993 • 38 citations

Glucose, glutamine and ketone body utilisation by resting and concanavalin A activated rat splenic lymphocytes

1989 • 37 citations

Formation of ketone bodies by resting lymphocytes

1989 • 34 citations

L-Asparaginase-Induced Immunosuppression: Effects on Antibody-Forming Cells and Serum Titers

1970 • 34 citations

Characterization of the effects of asparaginase from escherichia coli and a glutaminase‐free asparaginase from vibrio succinogenes on specific cell‐mediated cytotoxicity

1981 • 33 citations

Inhibition of immune responses by glutamine antagonism: effect of azotomycin on lymphocyte blastogenesis.

1971 • 33 citations

The exchange of blood-borne amino acids in the leg during abdominal surgical trauma: Effects of glucose infusion

1986 • 31 citations

Elevated glutamine metabolism in splenocytes from spontaneously diabetic BB rats

1991 • 31 citations

The immunodepressive activity of Escherichia coli L-asparaginase in some transplantation systems.

1970 • 30 citations

Pyruvate metabolism by lymphocytes: evidence for an additional ketogenic tissue.

1989 • 30 citations

Energy metabolism in thymic lymphocytes of normal and leukemia AKR mice.

1978 • 24 citations

Comparison of the L-asparaginases from Escherichia coli and Erwinia carotovora as immunosuppressants.

1974 • 22 citations

Effect of mitogens on the maximum activities of hexokinase, lactate dehydrogenase, citrate synthase and glutaminase in rat mesenteric lymph node lymphocytes and splenocytes during the early period of culture

1990 • 19 citations

Reversal by L-Glutamine of the Inhibition of Lymphocyte Mitosis Caused by E. coli Asparaginase

1970 • 15 citations

Intermittent high intensity exercise

1993 • 15 citations

Mechanism of action of polyunsaturated fatty acids in rheumatoid arthritis

1990 • 11 citations

Fatty acid oxidation by lymphocytes

1994 • 11 citations

Control of fructose 2,6-bisphosphate levels in rat macrophages by glucose and phorbol ester

1989 • 10 citations

Intracellular regulation of lipoprotein lipase in human monocyte-derived macrophages

1990 • 8 citations

The Overtraining Syndrome: Some Biochemical Aspects

2015 • 5 citations

Secretion of the lysosomal acid triacylglycerol hydrolase precursor by J774 Macrophages

1988 • 4 citations