The inhibition of T-lymphocyte proliferation by fatty acids is via an eicosanoid-independent mechanism.

Suppression of human T-cell mitogenesis by prostaglandin. Existence of a prostaglandin-producing suppressor cell.

1977 • 797 citations

Prostaglandin E inhibits the production of human interleukin 2.

1982 • 423 citations

Dietary polyunsaturated fatty acids and eicosanoids: potential effects on the modulation of inflammatory and immune cells: an overview.

1990 • 417 citations

Human lymphocyte metabolism. Effects of cyclic and noncyclic nucleotides on stimulation by phytohemagglutinin

1971 • 393 citations

Caffeic acid is a selective inhibitor for leukotriene biosynthesis

1984 • 349 citations

Prostaglandin E2 acts at two distinct pathways of T lymphocyte activation: inhibition of interleukin 2 production and down-regulation of transferrin receptor expression.

1985 • 311 citations

Lymphokine regulation of activated (G1) lymphocytes. I. Prostaglandin E2-induced inhibition of interleukin 2 production.

1983 • 266 citations

Essential fatty acids and immune response

1989 • 265 citations

Effect of temperature and antioxidants upon the lipoxidase-catalyzed oxidation of sodium linoleate

1953 • 206 citations

The stimulation of protein degradation in muscle by Ca2+ is mediated by prostaglandin E2 and does not require the calcium-activated protease.

1982 • 179 citations

Effect of lipoxygenase metabolites of arachidonic acid on proliferation of human T cells and T cell subsets.

1985 • 147 citations

Suppression of interleukin 2-dependent human T cell growth in vitro by prostaglandin E (PGE) and their precursor fatty acids. Evidence for a PGE-independent mechanism of inhibition by the fatty acids.

1990 • 139 citations

Prostaglandin E precursor fatty acids inhibit human IL-2 production by a prostaglandin E-independent mechanism

1990 • 134 citations

Prostaglandin E Modulation of the Mitogenic Response of Human T Cells

1979 • 132 citations

The regulation of prostaglandin biosynthesis by the manipulation of essential fatty acid metabolism.

1983 • 117 citations

Effect of fatty acids on the proliferation of concanavalin a-stimulated rat lymph node lymphocytes

1991 • 117 citations

The effect of the continuous re-infusion of lymph and lymphocytes on the output of lymphocytes from the thoracic duct of unanaesthetized rats.

1957 • 113 citations

Specific suppression of human T lymphocyte function by leukotriene B4.

1983 • 113 citations

Fatty acid metabolism in human lymphocytes. I. Time-course changes in fatty acid composition and membrane fluidity during blastic transformation of peripheral blood lymphocytes

1990 • 88 citations

Fatty acid metabolism in human lymphocytes. II. Activation of fatty acid desaturase-elongase systems during blastic transformation

1990 • 46 citations

Lymphocytes and arachidonic acid metabolism.

1988 • 35 citations

Modulation of lymphocyte activation. I. Inhibition by an oxidation product of arachidonic acid.

1980 • 31 citations

The effect of various concentrations of nucleobases, nucleosides or glutamine on the incorporation of [3H]thymidine into DNA in rat mesenteric-lymph-node lymphocytes stimulated by phytohaemagglutinin

1990 • 30 citations

Eicosanoid metabolism by lymphocytes: Do all human nucleated cells generate eicosanoids?

1989 • 24 citations

Fatty acid inhibition of concanavalin A-stimulated lymphocyte proliferation

1989 • 15 citations

Effect of inhibitors of eicosanoid synthesis upon lymphocyte proliferation

1991 • 2 citations