Essential fatty acids and immune response

Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological Effects

1987 • 2,237 citations

Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin.

1978 • 1,559 citations

Modulation of Inflammation and Immunity by Cyclic AMP

1974 • 923 citations

Regulation of the immune response by prostaglandins

1980 • 772 citations

Regulation of the immune response by prostaglandins

1983 • 717 citations

A Potential Second Messenger Role for Unsaturated Fatty Acids: Activation of Ca ²⁺ -Dependent Protein Kinase

1984 • 618 citations

Long-term effects of dietary marine omega-3 fatty acids upon plasma and cellular lipids, platelet function, and eicosanoid formation in humans.

1985 • 617 citations

Prostaglandins modulate macrophage Ia expression

1982 • 545 citations

The effect of dose level of essential fatty acids upon fatty acid composition of the rat liver

1963 • 482 citations

Prostaglandin E inhibits the production of human interleukin 2.

1982 • 423 citations

Human lymphocyte metabolism. Effects of cyclic and noncyclic nucleotides on stimulation by phytohemagglutinin

1971 • 393 citations

Nutrition and immunity.

1985 • 333 citations

Fatty Acids and Immunity

1978 • 230 citations

Dietary fish oil modulates macrophage fatty acids and decreases arthritis susceptibility in mice.

1985 • 215 citations

cis-Polyunsaturated fatty acids induce high levels of superoxide production by human neutrophils.

1981 • 208 citations

Human alveolar macrophage arachidonic acid metabolism

1988 • 199 citations

Antigen stimulation of prostaglandin synthesis and control of immune responses.

1976 • 184 citations

Role of prostaglandin E2 in the induction of nonspecific T lymphocyte suppressor activity.

1981 • 179 citations

Lipid Peroxidation by Human Blood Phagocytes

1974 • 177 citations

Inhibition of Prostaglandin Biosynthesis

1976 • 165 citations

The role of arachidonic acid metabolism in the activities of interleukin 1 and 2.

1985 • 163 citations

Effect of Inhibitors of Arachidonic Acid Metabolism on Mitogenesis in Human Lymphocytes: Possible Role of Thromboxanes and Products of the Lipoxygenase Pathway

1979 • 163 citations

Leukotriene B4 augments human natural cytotoxic cell activity

1983 • 155 citations

Activation of soluble splenic cell guanylate cyclase by prostaglandin endoperoxides and fatty acid hydroperoxides

1978 • 150 citations

Effect of lipoxygenase metabolites of arachidonic acid on proliferation of human T cells and T cell subsets.

1985 • 147 citations

Prevention of Glomerulonephritis and Prolonged Survival in New Zealand Black/New Zealand White F1 Hybrid Mice Fed an Essential Fatty Acid-deficient Diet

1981 • 145 citations

Phospholipid metabolism of stimulated lymphocytes

1975 • 135 citations

Dietary Linolenic Acid and Longer-Chain n-3 Fatty Acids: Comparison of Effects on Arachidonic Acid Metabolism in Rats

1988 • 134 citations

Dietary fish oil augments the induction of arthritis in rats immunized with type II collagen.

1984 • 125 citations

Influence of polyunsaturated fatty acids on survival of skin allografts and tumor incidence in mice.

1976 • 117 citations

Specific suppression of human T lymphocyte function by leukotriene B4.

1983 • 113 citations

Regulation of T-lymphocyte mitogenesis by the leukocyte product 15-hydroxy-eicosatetraenoic acid (15-HETE)

1982 • 109 citations

The role of prostaglandins in the control of the primary 19S immune response to sRBC

1977 • 108 citations

Differential effects of leukotriene B4 on T4+ and T8+ lymphocyte phenotype and immunoregulatory functions.

1985 • 107 citations

Effect of indomethacin in vivo on humoral and cellular immunity in humans

1978 • 95 citations

Arachidonic acid metabolism by murine peritoneal macrophages infected with Leishmania donovani: in vitro evidence for parasite-induced alterations in cyclooxygenase and lipoxygenase pathways.

1985 • 92 citations

Prostaglandin E2-Mediated Inactivation of Various Killer Lineage Cells by Tumor-Bearing Host Macrophages

1988 • 91 citations

Activation of soluble guanylate cyclase by arachidonic acid and 15-lipoxygenase products

1986 • 77 citations

Changes in the host natural killer cell population in mice during tumor development

1985 • 71 citations

Assessment of leukotriene B4 synthesis in human lymphocytes by using high performance liquid chromatography and radioimmunoassay methods.

1987 • 70 citations

Anti-PGE antibodies inhibit in vivo development of cell-mediated immunity

1981 • 69 citations

Partial reversal of the cellular immune defect in common variable immunodeficiency with indomethacin.

1978 • 59 citations

Essential Fatty Acid Depletion of Renal Allografts and Prevention of Rejection

1988 • 59 citations

Essential fatty acid deficiency depletes rat glomeruli of resident macrophages and inhibits angiotensin II-induced eicosanoid synthesis.

1987 • 52 citations

Enhancement of lymphocyte blastogenic and delayed hypersensitivity skin responses by indomethacin

1978 • 50 citations

Prostaglandin synthesis and release by subpopulations of rat alveolar macrophages.

1987 • 47 citations

Dietary fat, prostaglandins and the immune response.

1984 • 43 citations

Inhibition of Human NK Cell Cytotoxicity by Induction of Cyclic AMP Depends on Impaired Target Cell Recognition

1983 • 40 citations

Monocyte migration explains the changes in macrophage arachidonate metabolism during the immune response.

1986 • 40 citations

Modulation of macrophage-derived interleukin-1 and tumor necrosis factor by prostaglandin E2.

1987 • 31 citations

The effect of prostaglandin precursors in in vivo models of cell-mediated immunity

1981 • 29 citations

Inflammatory properties of lipoxygenase products and the effects of indomethacin and BW755C on prostaglandin production, leukocyte migration, and plasma exudation in rabbit skin.

1982 • 21 citations

LTB₄Production and Lysosomal Enzyme Release by Rat Alveolar Macrophages: Effects of Phagocytosis, Receptor Binding, and Ionophore Stimulation

1987 • 16 citations

Enhancement by prostaglandin E1 and essential fatty acid deficiency of the passive transfer of delayed hypersensitivity to PPD in rats. Comparison with effects on delayed hypersensitivity to SRBC in mice

1979 • 13 citations

Alleviation of murine autoimmune disease by dietary marine lipids.

1987 • 3 citations