Suppression of interleukin 2-dependent human T cell growth in vitro by prostaglandin E (PGE) and their precursor fatty acids. Evidence for a PGE-independent mechanism of inhibition by the fatty acids.

The Effect of Dietary Supplementation with n—3 Polyunsaturated Fatty Acids on the Synthesis of Interleukin-1 and Tumor Necrosis Factor by Mononuclear Cells

1989 • 1,951 citations

An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein

1984 • 1,132 citations

T‐Cell Growth Factor

1980 • 917 citations

The isolation and characterization of the human suppressor inducer T cell subset.

1985 • 860 citations

Suppression of human T-cell mitogenesis by prostaglandin. Existence of a prostaglandin-producing suppressor cell.

1977 • 797 citations

Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen.

1984 • 742 citations

Novel Interleukin-2 Receptor Subunit Detected by Cross-Linking Under High-Affinity Conditions

1986 • 585 citations

Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.

1987 • 565 citations

Fish-Oil Fatty Acid Supplementation in Active Rheumatoid Arthritis

1987 • 544 citations

Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway.

1984 • 506 citations

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

1982 • 494 citations

Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex.

1986 • 477 citations

Inhibition of murine natural killer cell activity by prostaglandins.

1980 • 418 citations

Control of lymphokine secretion by prostaglandins

1976 • 415 citations

Functional and Morphologic Characterization of Human T Cells Continuously Grown in Vitro

1977 • 410 citations

The interleukin 2 receptor. Functional consequences of its bimolecular structure.

1987 • 409 citations

Molecular order in cis and trans unsaturated phospholipid bilayers

1978 • 378 citations

A DOUBLE-BLIND, RANDOMISED, PLACEBO-CONTROLLED TRIAL OF FISH OIL IN PSORIASIS

1988 • 330 citations

Prostaglandin E2 acts at two distinct pathways of T lymphocyte activation: inhibition of interleukin 2 production and down-regulation of transferrin receptor expression.

1985 • 311 citations

A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors

1987 • 306 citations

Human T cell activation. II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen).

1985 • 285 citations

Soluble IL-2 receptor in rheumatoid arthritis. Correlation with disease activity, IL-1 and IL-2 inhibition.

1988 • 274 citations

Clonal dominance among T-lymphocyte infiltrates in arthritis.

1988 • 268 citations

Lymphokine regulation of activated (G1) lymphocytes. I. Prostaglandin E2-induced inhibition of interleukin 2 production.

1983 • 266 citations

Prostaglandin Suppression of Mitogen-Stimulated Lymphocytes In Vitro

1978 • 258 citations

Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors.

1987 • 252 citations

Ta1, a novel 105 KD human T cell activation antigen defined by a monoclonal antibody.

1984 • 239 citations

The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells.

1987 • 226 citations

Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study.

1988 • 218 citations

Prostaglandin inhibition of T-cell proliferation is mediated at two levels

1981 • 202 citations

Regulation of interleukin 2 synthesis by cAMP in human T cells.

1987 • 197 citations

Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes

1985 • 193 citations

The mechanisms of inhibition of human IL 2 production. II. PGE2 induction of suppressor T lymphocytes.

1984 • 186 citations

A double-blind, randomized placebo controlled trial on fish oil in psoriasis

1988 • 180 citations

Utilization of arachidonic and linoleic acids by cultured human endothelial cells.

1981 • 175 citations

Soluble interleukin‐2 receptors in systemic lupus erythematosus

1988 • 170 citations

Interleukin 2 regulates the expression of Tac antigen on peripheral blood T lymphocytes.

1984 • 156 citations

Detection of activated T cell products in the rheumatoid joint using cDNA probes to Interleukin-2 (IL-2) IL-2 receptor and IFN-gamma.

1988 • 147 citations

Involvement of T44 molecules in an antigen-independent pathway of T cell activation. Analysis of the correlations to the T cell antigen-receptor complex.

1985 • 142 citations

Prostaglandin E precursor fatty acids inhibit human IL-2 production by a prostaglandin E-independent mechanism

1990 • 134 citations

Prostaglandin E Modulation of the Mitogenic Response of Human T Cells

1979 • 132 citations

Effects of Arachidonic Acid and Other Unsaturated Fatty Acids on Mitogenesis in Human Lymphocytes

1979 • 132 citations

Differences in Cyclic AMP Changes after Stimulation by Prostaglandins and Isoproterenol in Lymphocyte Subpopulations

1975 • 131 citations

A novel pathway of human T cell activation via a 103 kD T cell activation antigen.

1987 • 130 citations

Prostaglandin E₂ and the increase of intracellular cAMP inhibit the expression of interleukin 2 receptors in human T cells

1988 • 129 citations

Target-effector interaction in the natural killer cell system. IV. Modulation by cyclic nucleotides.

1979 • 120 citations

Quantification of human platelet inositides and the influence of ionic environment on their incorporation of orthophosphate-32P

1971 • 117 citations

Contribution of a p75 interleukin 2 binding peptide to a high-affinity interleukin 2 receptor complex.

1987 • 115 citations

Suppression of monosodium urate crystal—induced acute inflammation by diets enriched with gamma‐linolenic acid and eicosapentaenoic acid

1988 • 99 citations

Analysis of prostaglandin E2 effect on T lymphocyte activation. Abrogation of prostaglandin E2 inhibitory effect by the tumor promotor 12.0 tetradecanoyl phorbol-13 acetate.

1987 • 92 citations

Glucose-induced phospholipid hydrolysis in isolated pancreatic islets: quantitative effects on the phospholipid content of arachidonate and other fatty acids

1986 • 90 citations

Spontaneous expression of the interleukin 2 receptor gene and presence of functional interleukin 2 receptors on T lymphocytes in the blood of individuals with active pulmonary sarcoidosis.

1988 • 82 citations

Levels of 13,14-dihydro-15-keto-PGE2 in some biological fluids as measured by radioimmunoassay

1977 • 72 citations

Response to and production of interleukin 2 by peripheral blood and cerebrospinal fluid lymphocytes of patients with multiple sclerosis.

1984 • 71 citations

Prostaglandin E2 inhibits human T-cell proliferation after crosslinking of the CD3-Ti complex by directly affecting T cells at an early step of the activation process

1987 • 70 citations

Insulin‐like growth factor‐I: Specific binding to high and low affinity sites and mitogenic action throughout the life span of WI‐38 cells

1987 • 67 citations

Effects of anti-proliferative cyclic AMP on interleukin 2-stimulated gene expression.

1987 • 57 citations

The role of cyclic AMP in modulating cytotoxic T lymphocytes. I. In-vivo-generated cytotoxic lymphocytes, but not in vitro-generated cytotoxic lymphocytes, are inhibited by cyclic AMP-active agents.

1979 • 57 citations

Regulation of the alternative pathway of T cell activation by anti-T3 monoclonal antibody

1986 • 55 citations

Prostaglandin E2-dependent induction of granulocyte-macrophage colony-stimulating factor secretion by cloned murine helper T cells.

1989 • 53 citations

Potentiation of lymphokine-activated killer cell differentiation and lymphocyte proliferation by stimulation of protein kinase C or inhibition of adenylate cyclase.

1988 • 49 citations

Separation of a population of human T lymphocytes that bind prostaglandin E2 and exert a suppressor activity.

1985 • 46 citations

Nutrition and Immunity: The Immunoregulatory Effect of n-6 Essential Fatty Acids Is Mediated through Prostaglandin E

1985 • 45 citations

Production of prostaglandin E2 by bladder tumor cells in tissue culture and a possible mechanism of lymphocyte inhibition

1979 • 44 citations

Prostaglandin synthesis in human T cells: its partial inhibition by lectins and anti-CD3 antibodies as a possible step in T cell activation.

1987 • 39 citations

Regulation of the alternative pathway of T cell activation by anti-T3 monoclonal antibody.

1986 • 38 citations

Interleukin-2 abnormalities in systemic lupus erythematosus and rheumatoid arthritis. A role for overproduction of interleukin-2 in human autoimmunity?

1988 • 36 citations

The Role of Cyclic AMP in Modulating Cytotoxic T Lymphocytes

1979 • 34 citations

Inhibition of in vitro proliferative response of cultured t lymphocytes to interleukin‐2 by gold sodium thiomalate

1988 • 30 citations

Stimulated T cell and natural killer (NK) cell lines fail to synthesize leukotriene B4

1987 • 27 citations

Phenotypic and functional characterization of T cell clones derived from the cerebrospinal fluid of multiple sclerosis patients.

1984 • 26 citations

Inhibition of interleukin 2‐induced proliferation of cloned murine T cells by glucocorticoids. Possible involvement of an inhibitory protein

1988 • 25 citations

Activated T lymphocytes in patients with multiple sclerosis in clinical remission

1987 • 19 citations

Suppression of B-cell and T-cell responses by the prostaglandin-induced T-cell-derived suppressor (PITS)

1984 • 17 citations

Role of cytokines in rheumatological inflammation.

1987 • 17 citations

The combined effect of prostaglandin E2 and interleukin 1 on interleukin 2 production and lymphocyte proliferation

1987 • 9 citations

Levels of 13,14-dihydro-15-keto-PGE2 in some biological fluids as measured by radioimmunoassay

1978 • 4 citations