Coupling of Human Circadian and Cell Cycles by the Timeless Protein

Coordination of circadian timing in mammals

2002 • 4,132 citations

Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints

2004 • 3,161 citations

The DNA damage response: putting checkpoints in perspective

2000 • 3,147 citations

Chk1 is an essential kinase that is regulated by Atr and required for the G₂/M DNA damage checkpoint

2000 • 1,583 citations

mCRY1 and mCRY2 Are Essential Components of the Negative Limb of the Circadian Clock Feedback Loop

1999 • 1,558 citations

The Circadian Gene Period2 Plays an Important Role in Tumor Suppression and DNA Damage Response In Vivo

2002 • 1,216 citations

Time zones: a comparative genetics of circadian clocks

2001 • 1,142 citations

Posttranslational Mechanisms Regulate the Mammalian Circadian Clock

2001 • 1,113 citations

Control Mechanism of the Circadian Clock for Timing of Cell Division in Vivo

2003 • 1,101 citations

Circadian Gene Expression in Individual Fibroblasts

2004 • 957 citations

ATR and ATRIP: Partners in Checkpoint Signaling

2001 • 935 citations

Toward Maintaining the Genome: DNA Damage and Replication Checkpoints

2002 • 773 citations

Bioluminescence Imaging of Individual Fibroblasts Reveals Persistent, Independently Phased Circadian Rhythms of Clock Gene Expression

2004 • 704 citations

Light-Independent Role of CRY1 and CRY2 in the Mammalian Circadian Clock

1999 • 613 citations

Molecular Genetics of Circadian Rhythms in Mammals

2000 • 541 citations

Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

2000 • 412 citations

Viewpoint: Putting the Cell Cycle in Order

1996 • 357 citations

Mammalian Circadian Autoregulatory Loop

1998 • 347 citations

Genome-wide Expression Analysis of Mouse Liver Reveals CLOCK-regulated Circadian Output Genes

2003 • 347 citations

Analysis of Clock Proteins in Mouse SCN Demonstrates Phylogenetic Divergence of the Circadian Clockwork and Resetting Mechanisms

2000 • 343 citations

ATR inhibition selectively sensitizes G ₁ checkpoint-deficient cells to lethal premature chromatin condensation

2001 • 289 citations

An ATR- and Chk1-Dependent S Checkpoint Inhibits Replicon Initiation following UVC-Induced DNA Damage

2002 • 242 citations

Requirement of Mammalian Timeless for Circadian Rhythmicity

2003 • 204 citations

Light Regulates the Cell Cycle in Zebrafish

2003 • 176 citations

Differential Regulation of mPER1 and mTIM Proteins in the Mouse Suprachiasmatic Nuclei: New Insights into a Core Clock Mechanism

1999 • 175 citations

A time-less function for mouse Timeless

2000 • 175 citations

Molecular Analysis of Mammalian Timeless

1998 • 169 citations

Swi1 Prevents Replication Fork Collapse and Controls Checkpoint Kinase Cds1

2003 • 164 citations

Chromosome cohesion is regulated by a clock gene paralogue TIM-1

2003 • 157 citations

Daily and Circadian Variation in Survival From Ultraviolet Radiation in Chlamydomonas reinhardtii

2000 • 139 citations

Regulation of the Mammalian Circadian Clock by Cryptochrome

2004 • 134 citations

Tof1p Regulates DNA Damage Responses During S Phase in Saccharomyces cerevisiae

2001 • 129 citations

The days and nights of cancer cells.

2003 • 111 citations

swi1 - and swi3 -dependent and independent replication fork arrest at the ribosomal DNA of Schizosaccharomyces pombe

2004 • 103 citations

Circadian variation of cell proliferation and cell cycle protein expression in man: Clinical implications

2000 • 102 citations

Quaternary Structure of ATR and Effects of ATRIP and Replication Protein A on Its DNA Binding and Kinase Activities

2004 • 102 citations

A second timeless gene in Drosophila shares greater sequence similarity with mammalian tim

2000 • 79 citations

Identification and characterization of the genes for two topoisomerase I-interacting proteins fromSaccharomyces cerevisiae

1999 • 76 citations

Identification of the mammalian homologues of the Drosophila timeless gene, Timeless1¹

1998 • 68 citations

Tipin, a Novel Timeless-Interacting Protein, is Developmentally Co-expressed with Timeless and Disrupts its Self-association

2003 • 62 citations

A role for Timeless in epithelial morphogenesis during kidney development

2000 • 41 citations

Timeless in lung morphogenesis

2003 • 30 citations

Cellular Clocks: Coupled Circadian and Cell Division Cycles

2004 • 24 citations