Mechanism of action of the papillomavirus E2 repressor: repression in the absence of DNA binding

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

The protein Id: A negative regulator of helix-loop-helix DNA binding proteins

1990 • 2,273 citations

Isolation of the bovine and human genes for müllerian inhibiting substance and expression of the human gene in animal cells

1986 • 997 citations

Electroporation for the efficient transfection of mammalian cells with DNA

1987 • 856 citations

Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II

1986 • 405 citations

Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product

1985 • 402 citations

The nucleotide sequence of the chick cytoplasmic β-actin gene

1983 • 336 citations

Bovine papillomavirus E2 trans-activating gene product binds to specific sites in papillomavirus DNA

1987 • 330 citations

A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator

1987 • 278 citations

I-POU: a POU-domain protein that inhibits neuron-specific gene activation

1991 • 217 citations

Structural and mutational analysis of E2 trans-activating proteins of papillomaviruses reveals three distinct functional domains.

1988 • 213 citations

Specific recognition nucleotides and their DNA context determine the affinity of E2 protein for 17 binding sites in the BPV-1 genome.

1989 • 195 citations

E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain.

1989 • 182 citations

Trans-activation of an upstream early gene promoter of bovine papilloma virus-1 by a product of the viral E2 gene.

1987 • 138 citations

The carboxy-terminal domain shared by the bovine papillomavirus E2 transactivator and repressor proteins contains a specific DNA binding activity.

1988 • 136 citations

Bovine papillomavirus type 1 encodes two forms of a transcriptional repressor: structural and functional analysis of new viral cDNAs

1989 • 130 citations

The specific DNA recognition sequence of the bovine papillomavirus E2 protein is an E2-dependent enhancer.

1988 • 124 citations

Expression and regulation of chicken actin genes introduced into mouse myogenic and nonmyogenic cells.

1984 • 114 citations

Bovine papilloma virus-transformed cells contain multiple E2 proteins.

1988 • 107 citations

A dimer of BPV-1 E2 containing a protease resistant core interacts with its DNA target.

1988 • 99 citations

The E2 "gene" of bovine papillomavirus encodes an enhancer-binding protein.

1987 • 98 citations

Sequence-specific and general transcriptional activation by the bovine papillomavirus-1 E2 trans-activator require an N-terminal amphipathic helix-containing E2 domain.

1988 • 81 citations

The activation domain of the bovine papillomavirus E2 protein mediates association of DNA-bound dimers to form DNA loops.

1991 • 78 citations

Genetic assignment of multiple E2 gene products in bovine papillomavirus-transformed cells

1989 • 73 citations

The bovine papillomavirus P2443 promoter is E2 trans-responsive: evidence for E2 autoregulation.

1988 • 65 citations

Amino acids necessary for DNA contact and dimerization imply novel motifs in the papillomavirus E2 trans-activator.

1992 • 56 citations

Cooperative binding of the E2 protein of bovine papillomavirus to adjacent E2-responsive sequences

1991 • 54 citations

Interaction of the bovine papillomavirus type 1 E2 transcriptional control protein with the viral enhancer: purification of the DNA-binding domain and analysis of its contact points with DNA

1988 • 53 citations

Evidence for cooperativity between E2 binding sites in E2 trans-regulation of bovine papillomavirus type 1

1988 • 52 citations

Trans activation by the bovine papillomavirus E2 protein in Saccharomyces cerevisiae

1989 • 39 citations

Bovine papillomavirus E2 gene regulates expression of the viral E5 transforming gene

1988 • 39 citations

Multiple cooperative interactions constrain BPV-1 E2 dependent activation of transcription

1989 • 29 citations

Multiplecis-active elements in the long control region of bovine papillomavirus type 1 (BPV-1)

1987 • 28 citations