Activation of Wee1 by p42 MAPK In Vitro and in CyclingXenopusEgg Extracts

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1991 • 1,463 citations

Transformation of Mammalian Cells by Constitutively Active MAP Kinase Kinase

1994 • 1,370 citations

Cyclin synthesis drives the early embryonic cell cycle

1989 • 1,223 citations

Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog

1987 • 1,004 citations

Chapter 30 Cell Cycle Extracts

1991 • 953 citations

cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2

1991 • 870 citations

Myt1: A Membrane-Associated Inhibitory Kinase That Phosphorylates Cdc2 on Both Threonine-14 and Tyrosine-15

1995 • 658 citations

Function of c-mos proto-oncogene product in meiotic maturation in Xenopus oocytes

1988 • 617 citations

The cdc25 protein contains an intrinsic phosphatase activity

1991 • 595 citations

The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell-free system

1991 • 504 citations

Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle.

1995 • 436 citations

Cell cycle tyrosine phosphorylation of p34cdc2 and a microtubule-associated protein kinase homolog in Xenopus oocytes and eggs.

1991 • 352 citations

The mitotic inducer nim1+ functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis

1987 • 334 citations

A link between MAP kinase and p34cdc2/cyclin B during oocyte maturation: p90rsk phosphorylates and inactivates the p34cdc2 inhibitory kinase Myt1

1998 • 319 citations

Requirements for Phosphorylation of Map Kinase During Meiosis in Xenopus Oocytes

1992 • 316 citations

Cell cycle regulation of a Xenopus Wee1-like kinase.

1995 • 316 citations

Cell cycle extracts.

1991 • 304 citations

Cell cycle regulation of human WEE1.

1995 • 281 citations

Meiotic initiation by the mos protein in Xenopus

1992 • 253 citations

Mechanisms Regulating Pattern Formation in the Amphibian Egg and Early Embryo

1980 • 250 citations

Requirement for the MAP kinase kinase/MAP kinase cascade in Xenopus oocyte maturation.

1994 • 207 citations

Negative regulation of the weel protein kinase by direct action of the nim1/cdr1 mitotic inducer

1993 • 184 citations

Chapter 17 Systems for the Study of Nuclear Assembly, DNA Replication, and Nuclear Breakdown in Xenopus laevis Egg Extracts

1991 • 180 citations

Independent inactivation of MPF and cytostatic factor (Mos) upon fertilization of Xenopus eggs

1991 • 174 citations

Initiation of Xenopus Oocyte Maturation by Activation of the Mitogen-activated Protein Kinase Cascade

1995 • 172 citations

[12] Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes

1991 • 170 citations

The Protein Kinase p90 Rsk as an Essential Mediator of Cytostatic Factor Activity

1999 • 163 citations

Nim1 kinase promotes mitosis by inactivating Wee1 tyrosine kinase

1993 • 161 citations

Phosphorylation and inactivation of the mitotic inhibitor Weel by the nim1/cdr1 kinase

1993 • 156 citations

Induction of Xenopus Oocyte Meiotic Maturation by MAP Kinase

1995 • 154 citations

In VivoRegulation of the Early Embryonic Cell Cycle inXenopus

1996 • 148 citations

Interdependent Domains Controlling the Enzymatic Activity of Mitogen-Activated Protein Kinase Kinase 1

1996 • 134 citations

The Early Development of Xenopus Laevis: An Atlas of the Histology

1991 • 120 citations

Evidence that inactive p42 mitogen-activated protein kinase and inactive Rsk exist as a heterodimer in vivo.

1994 • 116 citations

Biochemical and biological analysis of Mek1 phosphorylation site mutants.

1995 • 113 citations

Analysis of the early embryonic cell cycles of Xenopus; regulation of cell cycle length by Xe-wee1 and Mos

1998 • 107 citations

MAP Kinase Is Required for the Spindle Assembly Checkpoint but Is Dispensable for the Normal M Phase Entry and Exit in Xenopus Egg Cell Cycle Extracts

1997 • 102 citations

Genetic and molecular analysis of cdr1/nim1 in Schizosaccharomyces pombe.

1991 • 102 citations

A Role for Mitogen-activated Protein Kinase in the Spindle Assembly Checkpoint in XTC Cells

1997 • 100 citations

Requirement for MAPK Activation for Normal Mitotic Progression in Xenopus Egg Extracts

1998 • 90 citations

Cell Cycle Tyrosine Phosphorylation of p34^cdc2 and a Microtubule- Associated Protein Kinase Homolog in Xenopus Oocytes and Eggs

1991 • 79 citations

MAPK inactivation is required for the G2 to M-phase transition of the first mitotic cell cycle

1997 • 76 citations

Constitutively active mitogen-activated protein kinase kinase 1 (MAPKK1) and MAPKK2 mediate similar transcriptional and morphological responses.

1996 • 62 citations

MAP kinase does not inactivate, but rather prevents the cyclin degradation pathway from being turned on in Xenopus egg extracts

1996 • 61 citations

Activation of the p42 Mitogen-activated Protein Kinase Pathway Inhibits Cdc2 Activation and Entry into M-Phase in CyclingXenopusEgg Extracts

1998 • 61 citations

Induction of a G₂-Phase Arrest inXenopusEgg Extracts by Activation of p42 Mitogen-activated Protein Kinase

1997 • 59 citations

MAP Kinase Is Activated during Mesoderm Induction in Xenopus laevis

1994 • 54 citations

PD 98059 Prevents Establishment of the Spindle Assembly Checkpoint and Inhibits the G2-M Transition in Meiotic but Not Mitotic Cell Cycles inXenopus

1998 • 45 citations

Distinct, Constitutively Active MAPK Phosphatases Function inXenopusOocytes: Implications for p42 MAPK Regulation In Vivo

1999 • 41 citations

Mitogen-activated protein kinase activation down-regulates a mechanism that inactivates cyclin B-cdc2 kinase in G2-arrested oocytes.

1997 • 39 citations

Mos positively regulates Xe-Wee1 to lengthen the first mitotic cell cycle of Xenopus

1999 • 39 citations

Inactivation of p42 Mitogen-activated Protein Kinase Is Required for Exit from M-phase after Cyclin Destruction

1999 • 22 citations

Isolation and Characterization of Neutralizing Single-Chain Antibodies againstXenopusMitogen-Activated Protein Kinase Kinase from Phage Display Libraries

1996 • 13 citations