Normal and abnormal neuronal migration in the developing cerebral cortex.

Specification of Cerebral Cortical Areas

1988 • 3,021 citations

Mode of cell migration to the superficial layers of fetal monkey neocortex

1972 • 2,145 citations

A protein related to extracellular matrix proteins deleted in the mouse mutant reeler

1995 • 1,720 citations

Stem Cells in the Central Nervous System

1997 • 1,483 citations

Doublecortin Is a Microtubule-Associated Protein and Is Expressed Widely by Migrating Neurons

1999 • 1,297 citations

Neuronal migration, with special reference to developing human brain: a review

1973 • 1,239 citations

Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2

1999 • 1,231 citations

doublecortin, a Brain-Specific Gene Mutated in Human X-Linked Lissencephaly and Double Cortex Syndrome, Encodes a Putative Signaling Protein

1998 • 1,019 citations

Direct Binding of Reelin to VLDL Receptor and ApoE Receptor 2 Induces Tyrosine Phosphorylation of Disabled-1 and Modulates Tau Phosphorylation

1999 • 902 citations

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

1996 • 901 citations

The reeler gene-associated antigen on cajal-retzius neurons is a crucial molecule for laminar organization of cortical neurons

1995 • 882 citations

Mutations in filamin 1 Prevent Migration of Cerebral Cortical Neurons in Human Periventricular Heterotopia

1998 • 858 citations

CENTRAL NERVOUS SYSTEM NEURONAL MIGRATION

1999 • 808 citations

Reelin Is a Ligand for Lipoprotein Receptors

1999 • 803 citations

A Novel CNS Gene Required for Neuronal Migration and Involved in X-Linked Subcortical Laminar Heterotopia and Lissencephaly Syndrome

1998 • 740 citations

Src family kinases are required for integrin but not PDGFR signal transduction

1999 • 733 citations

Mice Lacking p35, a Neuronal Specific Activator of Cdk5, Display Cortical Lamination Defects, Seizures, and Adult Lethality

1997 • 727 citations

Cell Cycle Dependence of Laminar Determination in Developing Neocortex

1991 • 718 citations

Embryonic vertebrate central nervous system: Revised terminology

1970 • 716 citations

Neuronal position in the developing brain is regulated by mouse disabled-1

1997 • 698 citations

Mendelian Inheritance in Man: A Catalog of Human Genes and Genetic Disorders

1998 • 693 citations

Principles of neural cell migration

1990 • 659 citations

Scrambler and yotari disrupt the disabled gene and produce a reeler -like phenotype in mice

1997 • 637 citations

Neocortical histogenesis in normal and reeler mice: A developmental study based upon [3H]thymidine autoradiography

1982 • 629 citations

Mechanisms of Neural Patterning and Specification in the Development Cerebellum

1995 • 574 citations

Expression of Constitutively Active α-PAK Reveals Effects of the Kinase on Actin and Focal Complexes

1997 • 560 citations

Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse.

1998 • 528 citations

Reelin Is a Secreted Glycoprotein Recognized by the CR-50 Monoclonal Antibody

1997 • 512 citations

Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor

1994 • 473 citations

Cajal–Retzius cells and the development of the neocortex

1998 • 431 citations

The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity

1998 • 403 citations

Coexistence of neuronal and glial precursor cells in the cerebral ventricular zone of the fetal monkey: an ultrastructural immunoperoxidase analysis

1981 • 397 citations

Reelin is preferentially expressed in neurons synthesizing γ-aminobutyric acid in cortex and hippocampus of adult rats

1998 • 384 citations

Mouse disabled (mDab1): a Src binding protein implicated in neuronal development

1997 • 337 citations

Lissencephaly and Other Malformations of Cortical Development: 1995 Update

1995 • 323 citations

Cyclin-Dependent Kinase 5-Deficient Mice Demonstrate Novel Developmental Arrest in Cerebral Cortex

1998 • 315 citations

Periventricular Heterotopia: An X-Linked Dominant Epilepsy Locus Causing Aberrant Cerebral Cortical Development

1996 • 301 citations

Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories.

1996 • 286 citations

The development of the cerebral cortex in the embryonic mouse: An electron microscopic serial section analysis

1978 • 282 citations

Cajal—Retzius cells, Reelin, and the formation of layers

1998 • 278 citations

Proteins of the CNR Family Are Multiple Receptors for Reelin

1999 • 276 citations

A mouse model for Zellweger syndrome

1997 • 271 citations

Aberrant Splicing of a Mouse disabled Homolog, mdab1, in the scrambler Mouse

1997 • 263 citations

Phenotype of patients with peroxisomal disorders subdivided into sixteen complementation groups

1995 • 246 citations

Glutamate-like Immunoreactivity and Fate of Cajal-Retzius Cells in the Murine Cortex as Identified with Calretinin Antibody

1995 • 242 citations

Obstructed neuronal migration along radial glial fibers in the neocortex of the reeler mouse: A golgi-EM analysis

1982 • 240 citations

X-linked malformations of neuronal migration

1996 • 240 citations

Neuronal-glial interaction during brain development

1981 • 239 citations

Midkine, A Retinoic Acid-Inducible Growth/Differentiation Factor: Immunochemical Evidence for the Function and Distribution

1993 • 229 citations

Reelin mRNA Expression During Mouse Brain Development

1997 • 226 citations

Differences in the gyral pattern distinguish chromosome 17–linked and X-linked lissencephaly

1999 • 224 citations

Migration of Cortical Neurons Is Altered by Gestational Exposure to Ethanol

1993 • 219 citations

The functions of the preplate in development and evolution of the neocortex and hippocampus

1998 • 213 citations

Mitochondrial Alterations Caused by Defective Peroxisomal Biogenesis in a Mouse Model for Zellweger Syndrome (PEX5 Knockout Mouse)

2001 • 197 citations

The Reeler Mouse as a Model of Brain Development

1998 • 181 citations

Prenatal development of reelin-immunoreactive neurons in the human neocortex

1998 • 174 citations

Effect of Prenatal Exposure to Ethanol on the Development of Cerebral Cortex: I. Neuronal Generation

1988 • 173 citations

Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5.

1997 • 157 citations

The role of migration in central nervous system neuronal development

1993 • 156 citations

Reeler: new tales on an old mutant mouse

1998 • 154 citations

Targeted Deletion of the PEX2 Peroxisome Assembly Gene in Mice Provides a Model for Zellweger Syndrome, a Human Neuronal Migration Disorder

1997 • 152 citations

The history of radial glia

1999 • 149 citations

Phosphorylation of the High Molecular Weight Neurofilament Protein (NF-H) by Cdk5 and p35

1996 • 148 citations

A Genetic Animal Model of Human Neocortical Heterotopia Associated with Seizures

1997 • 140 citations

Abnormal reorganization of preplate neurons and their associated extracellular matrix: An early manifestation of altered neocortical development in the reeler mutant mouse

1997 • 140 citations

A novel neurological mutant mouse, yotari, which exhibits reeler-like phenotype but expresses CR-50 antigen/Reelin

1997 • 138 citations

Cajal-Retzius Cells Regulate the Radial Glia Phenotype in the Adult and Developing Cerebellum and Alter Granule Cell Migration

1997 • 134 citations

Dual role of Cajal-Retzius cells and reelin in cortical development

1997 • 131 citations

Cocaine-induced disturbances of corticogenesis in the developing murine brain

1992 • 126 citations

Secretion and biological activities of heparin-binding growth-associated molecule. Neurite outgrowth-promoting and mitogenic actions of the recombinant and tissue-derived protein.

1992 • 118 citations

Birthdate and Cell Marker Analysis of Scrambler: A Novel Mutation Affecting Cortical Development with a Reeler-Like Phenotype

1997 • 114 citations

Prenatal Methylazoxymethanol Treatment in Rats Produces Brain Abnormalities with Morphological Similarities to Human Developmental Brain Dysgeneses

1999 • 107 citations

Distribution of a reeler gene-related antigen in the developing cerebellum: An immunohistochemical study with an allogeneic antibody CR-50 on normal and reeler mice

1996 • 106 citations

Cell migration and neuronal ectopias in the brain.

1975 • 104 citations

Dynamical aspects of neocortical histogenesis in the rat

1980 • 102 citations

Bilateral periventricular nodular heterotopia with mental retardation and syndactyly in boys: A new X-linked mental retardation syndrome

1997 • 98 citations

Linkage and physical mapping of X-linked lissencephaly/SBH (XLIS): a gene causing neuronal migration defects in human brain

1997 • 96 citations

The mouse mutation reeler causes increased adhesion within a subpopulation of early postmitotic cortical neurons

1995 • 93 citations

A novel family of heparin-binding growth factors, pleiotrophin and midkine, is expressed in the developing rat cerebral cortex

1994 • 86 citations

Glial-Neuronal Relationship in the Developing Central Nervous System

1985 • 81 citations

Platelet-Activating Factor Acetylhydrolase Expression and Activity Suggest a Link between Neuronal Migration and Platelet-Activating Factor

1996 • 81 citations

Developmental‐stage‐dependent radiosensitivity of neural cells in the ventricular zone of telencephalon in mouse and rat fetuses

1988 • 78 citations

Characterization of heterotopic cell clusters in the hippocampus of rats exposed to methylazoxymethanol in utero

2000 • 78 citations

Congenital Malformations of the Brain. Pathologic, Embryologic, Clinical, Radiologic and Genetic Aspects

1996 • 78 citations

Phosphorylation by Neuronal cdc2-like Protein Kinase Promotes Dimerization of Tau Protein in Vitro

1997 • 76 citations

Phosphorylation of human high molecular weight neurofilament protein (hNF-H) by neuronal cyclin-dependent kinase 5 (cdk5)

1997 • 68 citations

Altered connections between neocortical and heterotopic areas in methylazoxymethanol-treated rat

1998 • 66 citations

Topographical and Cytological Evolution of the Glial Phase During Prenatal Development of the Human Brain: Histochemical and Electron Microscopic Study

1988 • 65 citations

Disordered migration and loss of virus-infected neuronal cells in developing mouse brains infected with murine cytomegalovirus

1997 • 63 citations

Localization of Heparin-Binding, Neurite Outgrowth and Antigenic Regions in Midkine Molecule

1994 • 58 citations

Lissencephaly gene product. Localization in the central nervous system and loss of immunoreactivity in Miller-Dieker syndrome.

1995 • 53 citations

Predominant Localization of the LIS Family of Gene Products to Cajal-Retzius Cells and Ventricular Neuroepithelium in the Developing Human Cortex

1997 • 51 citations

The Midkine Family of Growth/ Differentiation Factors

1994 • 48 citations

The Neuronal Migration Defect in Mice with Zellweger Syndrome (Pex5Knockout) is not Caused by the Inactivity of Peroxisomal β-Oxidation

2002 • 47 citations

A new view of early cortical development

1998 • 45 citations

Abnormalities of cerebellar foliation in rats prenatally exposed to ethanol

2001 • 41 citations

Isolation from Bovine Brain and Structural Characterization of HBNF, a Heparin-Binding Neurotrophic Factor

1991 • 36 citations

An Immunohistochemical Study of Radial Glial Cells in the Mouse Brain Prenatally Exposed to γ-irradiation

1997 • 35 citations

Zellweger Syndrome Knockout Mouse Models Challenge Putative Peroxisomal β-Oxidation Involvement in Docosahexaenoic Acid (22:6n-3) Biosynthesis

2001 • 28 citations

Astrotactin (ASTN), a Gene for Glial-Guided Neuronal Migration, Maps to Human Chromosome 1q25.2

1997 • 27 citations

Different patterns of abnormal neuronal migration in the cerebral cortex of mice prenatally exposed to irradiation

1999 • 21 citations

Effects of different doses of gamma-radiation on the developing brain of mice.

1995 • 17 citations

Neurogenesis of heterotopic gray matter in the brain of the microcephalic mouse

2001 • 15 citations

Midkine and secondary neurulation

1997 • 15 citations

The behavior of the reeler neurological mutant mouse.

1968 • 15 citations

Types and Three-dimensional Distribution of Neuronal Ectopias in the Brain of Mice Prenatally Subjected to X-irradiation

2002 • 12 citations

Follow-up study on histogenesis of microcephaly associated with ectopic gray matter induced by prenatal γ -irradiation in the mouse

1996 • 8 citations

Midkine, A New Heparin‐Binding Growth/Differentiation Factor: Expression and Distribution during Embryogenesis and Pathological Status

1998 • 2 citations