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Mice Lacking p35, a Neuronal Specific Activator of Cdk5, Display Cortical Lamination Defects, Seizures, and Adult Lethality

Data up to Jan 2025

Published1997
Citations727
References41

Total Citations Per Year

Abstract

References (41)

Theory and Practice of Histological Techniques

1990 • 6,957 citations

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1992 • 3,907 citations

Stimulus-Transcription Coupling in the Nervous System: Involvement of the Inducible Proto-Oncogenes fos and jun

1991 • 2,666 citations

Altering the Genome by Homologous Recombination

1989 • 2,021 citations

Mapping Patterns of c- fos Expression in the Central Nervous System After Seizure

1987 • 1,771 citations

Two methods for selective silver impregnation of degenerating axons and their synaptic endings in the central nervous system

1967 • 1,751 citations

A protein related to extracellular matrix proteins deleted in the mouse mutant reeler

1995 • 1,720 citations

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1988 • 1,690 citations

Autoradiographic Study of Cell Migration during Histogenesis of Cerebral Cortex in the Mouse

1961 • 1,488 citations

Two Visual Systems

1969 • 1,372 citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1991 • 1,317 citations

A family of human cdc2-related protein kinases.

1992 • 928 citations

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

1994 • 915 citations

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

1996 • 901 citations

The reeler gene-associated antigen on cajal-retzius neurons is a crucial molecule for laminar organization of cortical neurons

1995 • 882 citations

Theory and Practice of Histological Techniques

1977 • 840 citations

Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazole: Metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy

1981 • 654 citations

Mechanisms of Cortical Development: A View From Mutations in Mice

1978 • 653 citations

Neocortical histogenesis in normal and reeler mice: A developmental study based upon [3H]thymidine autoradiography

1982 • 629 citations

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation.

1996 • 592 citations

A brain-specific activator of cyclin-dependent kinase 5

1994 • 575 citations

Two new mutants, ‘trembler’ and ‘reeler’, with neurological actions in the house mouse (Mus musculus L.)

1951 • 517 citations

Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system

1993 • 453 citations

Identification of radial glial cells within the developing murine central nervous system: studies based upon a new immunohistochemical marker

1988 • 428 citations

Time of origin of corresponding cell classes in the cerebral cortex of normal and reeler mutant mice: An autoradiographic analysis

1973 • 412 citations

An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator

1995 • 342 citations

Neurogenesis of the cat's primary visual cortex

1985 • 334 citations

Cortical development: View from neurological mutants two decades later

1995 • 284 citations

Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression.

1992 • 275 citations

Events governing organization of postmigratory neurons: Studies on brain development in normal and reeler mice

1984 • 250 citations

BUdR as an S-phase marker for quantitative studies of cytokinetic behaviour in the murine cerebral ventricular zone

1992 • 241 citations

Purification and characterization of a novel proline-directed protein kinase from bovine brain.

1992 • 238 citations

The development of hippocampal and dorsolateral pallial regions of the cerebral hemisphere in fetal rabbits. I. Fifteen millimeter stage, spongioblast morphology

1967 • 227 citations

Patterns of cell and fiber distribution in the neocortex of the reeler mutant mouse

1976 • 225 citations

Neuronal cdc2-like kinase

1995 • 179 citations

Determinants of cell shape and orientation: A comparative Golgi analysis of cell‐axon interrelationships in the developing neocortex of normal and reeler mice

1979 • 159 citations

Causal heterogeneity in isolated lissencephaly

1992 • 139 citations

The mouse mutation reeler causes increased adhesion within a subpopulation of early postmitotic cortical neurons

1995 • 93 citations

The development of hippocampal and dorsolateral pallial regions of the cerebral hemisphere in fetal rabbits. VI. Ninety millimeter stage, cortical differentiation

1968 • 80 citations

Temporal and spatial patterns of expression of p35, a regulatory subunit of cyclin-dependent kinase 5, in the nervous system of the mouse.

1997 • 79 citations

Localization and developmental changes in the neuron-specific cyclin-dependent kinase 5 activator (p35nck5a) in the rat brain

1996 • 53 citations

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Mice Lacking p35, a Neuronal Specific Activator of Cdk5, Display Cortical Lamination… (1997) – Neuron | Metascience Observatory Explorer