Mice Lacking p35, a Neuronal Specific Activator of Cdk5, Display Cortical Lamination Defects, Seizures, and Adult Lethality
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References (41)
Theory and Practice of Histological Techniques
1990 • 6,957 citations
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
1992 • 3,907 citations
Stimulus-Transcription Coupling in the Nervous System: Involvement of the Inducible Proto-Oncogenes fos and jun
1991 • 2,666 citations
Altering the Genome by Homologous Recombination
1989 • 2,021 citations
Mapping Patterns of c- fos Expression in the Central Nervous System After Seizure
1987 • 1,771 citations
Two methods for selective silver impregnation of degenerating axons and their synaptic endings in the central nervous system
1967 • 1,751 citations
A protein related to extracellular matrix proteins deleted in the mouse mutant reeler
1995 • 1,720 citations
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
1988 • 1,690 citations
Autoradiographic Study of Cell Migration during Histogenesis of Cerebral Cortex in the Mouse
1961 • 1,488 citations
Two Visual Systems
1969 • 1,372 citations
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
1991 • 1,317 citations
A family of human cdc2-related protein kinases.
1992 • 928 citations
p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5
1994 • 915 citations
Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.
1996 • 901 citations
The reeler gene-associated antigen on cajal-retzius neurons is a crucial molecule for laminar organization of cortical neurons
1995 • 882 citations
Theory and Practice of Histological Techniques
1977 • 840 citations
Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazole: Metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy
1981 • 654 citations
Mechanisms of Cortical Development: A View From Mutations in Mice
1978 • 653 citations
Neocortical histogenesis in normal and reeler mice: A developmental study based upon [3H]thymidine autoradiography
1982 • 629 citations
The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation.
1996 • 592 citations
A brain-specific activator of cyclin-dependent kinase 5
1994 • 575 citations
Two new mutants, ‘trembler’ and ‘reeler’, with neurological actions in the house mouse (Mus musculus L.)
1951 • 517 citations
Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system
1993 • 453 citations
Identification of radial glial cells within the developing murine central nervous system: studies based upon a new immunohistochemical marker
1988 • 428 citations
Time of origin of corresponding cell classes in the cerebral cortex of normal and reeler mutant mice: An autoradiographic analysis
1973 • 412 citations
An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator
1995 • 342 citations
Neurogenesis of the cat's primary visual cortex
1985 • 334 citations
Cortical development: View from neurological mutants two decades later
1995 • 284 citations
Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression.
1992 • 275 citations
Events governing organization of postmigratory neurons: Studies on brain development in normal and reeler mice
1984 • 250 citations
BUdR as an S-phase marker for quantitative studies of cytokinetic behaviour in the murine cerebral ventricular zone
1992 • 241 citations
Purification and characterization of a novel proline-directed protein kinase from bovine brain.
1992 • 238 citations
The development of hippocampal and dorsolateral pallial regions of the cerebral hemisphere in fetal rabbits. I. Fifteen millimeter stage, spongioblast morphology
1967 • 227 citations
Patterns of cell and fiber distribution in the neocortex of the reeler mutant mouse
1976 • 225 citations
Neuronal cdc2-like kinase
1995 • 179 citations
Determinants of cell shape and orientation: A comparative Golgi analysis of cell‐axon interrelationships in the developing neocortex of normal and reeler mice
1979 • 159 citations
Causal heterogeneity in isolated lissencephaly
1992 • 139 citations
The mouse mutation reeler causes increased adhesion within a subpopulation of early postmitotic cortical neurons
1995 • 93 citations
The development of hippocampal and dorsolateral pallial regions of the cerebral hemisphere in fetal rabbits. VI. Ninety millimeter stage, cortical differentiation
1968 • 80 citations
Temporal and spatial patterns of expression of p35, a regulatory subunit of cyclin-dependent kinase 5, in the nervous system of the mouse.
1997 • 79 citations
Localization and developmental changes in the neuron-specific cyclin-dependent kinase 5 activator (p35nck5a) in the rat brain
1996 • 53 citations