Reeler: new tales on an old mutant mouse

A protein related to extracellular matrix proteins deleted in the mouse mutant reeler

1995 • 1,720 citations

Autoradiographic Study of Cell Migration during Histogenesis of Cerebral Cortex in the Mouse

1961 • 1,488 citations

Neuron‐glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electonmicroscopic study in Macacus rhesus

1971 • 1,334 citations

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

1996 • 901 citations

The reeler gene-associated antigen on cajal-retzius neurons is a crucial molecule for laminar organization of cortical neurons

1995 • 882 citations

Mice Lacking p35, a Neuronal Specific Activator of Cdk5, Display Cortical Lamination Defects, Seizures, and Adult Lethality

1997 • 727 citations

Neuronal position in the developing brain is regulated by mouse disabled-1

1997 • 698 citations

Mechanisms of Cortical Development: A View From Mutations in Mice

1978 • 653 citations

Scrambler and yotari disrupt the disabled gene and produce a reeler -like phenotype in mice

1997 • 637 citations

Neocortical histogenesis in normal and reeler mice: A developmental study based upon [3H]thymidine autoradiography

1982 • 629 citations

Guidance of neurons migrating to the fetal monkey neocortex

1971 • 578 citations

Catalog of the Neurological Mutants of the Mouse

1965 • 520 citations

Two new mutants, ‘trembler’ and ‘reeler’, with neurological actions in the house mouse (Mus musculus L.)

1951 • 517 citations

Reelin Is a Secreted Glycoprotein Recognized by the CR-50 Monoclonal Antibody

1997 • 512 citations

Dual origin of the mammalian neocortex and evolution of the cortical plate

1978 • 503 citations

A role for Cajal–Retzius cells and reelin in the development of hippocampal connections

1997 • 467 citations

Exon amplification: a strategy to isolate mammalian genes based on RNA splicing.

1991 • 425 citations

Anatomical, Physiological and biochemical studies of the cerebellum fromreelermutant mouse

1977 • 398 citations

F-spondin: A gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension

1992 • 382 citations

The reeler gene encodes a protein with an EGF–like motif expressed by pioneer neurons

1995 • 347 citations

Mouse disabled (mDab1): a Src binding protein implicated in neuronal development

1997 • 337 citations

Cortical development: View from neurological mutants two decades later

1995 • 284 citations

Aberrant Splicing of a Mouse disabled Homolog, mdab1, in the scrambler Mouse

1997 • 263 citations

Events governing organization of postmigratory neurons: Studies on brain development in normal and reeler mice

1984 • 250 citations

Drosophila abl tyrosine kinase in embryonic CNS axons: A role in axonogenesis is revealed through dosage-sensitive interactions with disabled

1989 • 240 citations

Obstructed neuronal migration along radial glial fibers in the neocortex of the reeler mouse: A golgi-EM analysis

1982 • 240 citations

Reelin mRNA Expression During Mouse Brain Development

1997 • 226 citations

Patterns of cell and fiber distribution in the neocortex of the reeler mutant mouse

1976 • 225 citations

Regulation of Purkinje Cell Alignment by Reelin as Revealed with CR-50 Antibody

1997 • 178 citations

Disruption of hippocampal development in vivo by CR-50 mAb against Reelin

1997 • 169 citations

Cerebellar Disorganization Characteristic of Reeler in Scrambler Mutant Mice Despite Presence of Reelin

1997 • 161 citations

Scrambler, a new neurological mutation of the mouse with abnormalities of neuronal migration

1996 • 154 citations

The embryonic development of the cerebellum in normal and reeler mutant mice

1983 • 145 citations

Abnormal reorganization of preplate neurons and their associated extracellular matrix: An early manifestation of altered neocortical development in the reeler mutant mouse

1997 • 140 citations

A novel neurological mutant mouse, yotari, which exhibits reeler-like phenotype but expresses CR-50 antigen/Reelin

1997 • 138 citations

Cloning of a Novel Phosphoprotein Regulated by Colony-stimulating Factor 1 Shares a Domain with the Drosophiladisabled Gene Product

1995 • 136 citations

A truncated Reelin protein is produced but not secreted in the ‘Orleans’ reeler mutation (Reln)

1997 • 126 citations

Alignment defect of reaggregating cells in cultures of developing brains of reeler mutant mice

1970 • 125 citations

Birthdate and Cell Marker Analysis of Scrambler: A Novel Mutation Affecting Cortical Development with a Reeler-Like Phenotype

1997 • 114 citations

Distribution of a reeler gene-related antigen in the developing cerebellum: An immunohistochemical study with an allogeneic antibody CR-50 on normal and reeler mice

1996 • 106 citations

Dysfunction of the Orleans reeler gene arising from exon skipping due to transposition of a full-length copy of an active L1 sequence into the skipped exon

1996 • 99 citations

Functions of netrins and semaphorins in axon guidance

1996 • 98 citations

Detection of the reelin breakpoint in reeler mice

1996 • 95 citations

The mouse mutation reeler causes increased adhesion within a subpopulation of early postmitotic cortical neurons

1995 • 93 citations

Obstructed migration of Purkinje cells in the developing cerebellum of the reeler mutant mouse

1993 • 91 citations

A YAC contig containing the reeler locus with preliminary characterization of candidate gene fragments

1995 • 84 citations

Genomic Organization of the MouseReelinGene

1997 • 80 citations

Observations on the neuropathology of ‘reeler’, a neurological mutation in mice

1960 • 60 citations

Isolation of an allele of reeler by insertional mutagenesis.

1994 • 57 citations

An electrophysiological study of the hippocampus of the ‘reeler’ mutant mouse

1974 • 45 citations

Reeler mutant mouse: maintenance of appropriate and reciprocal connections in the cerebral cortex and thalamus

1976 • 41 citations

Chlorambucil-induced mutations in mice recovered in homozygotes.

1992 • 40 citations

Suppressed T Cell and Macrophage Function in the "Reeler" (rl/rl) Mutant, a Murine Strain with Elevated Cerebellar Norepinephrine Concentration

1995 • 34 citations

Evidence for the occurence of early modifications in the ‘glia limitans’ layer of the neocortex of the reeler mutant mouse

1979 • 33 citations

Chromosome abnormality in Kallmann syndrome

1990 • 27 citations

Relnrl-Alb2,an Allele ofReelerIsolated from a Chlorambucil Screen, Is Due to an IAP Insertion with Exon Skipping

1997 • 23 citations

A High-Resolution Genetic Map of Mouse Chromosome 5 Encompassing the Reeler (rl) Locus

1994 • 20 citations

Localization of thereeler gene relative to flanking loci on mouse chromosome 5

1991 • 17 citations

Cerebellum of the adult reeler mutant mouse contains two Purkinje cell populations with respect to gene expression for the N-methyl-d-aspartate receptor channel

1995 • 16 citations

High-resolution genetic map and YAC contig around the mouse neurological locus reeler

1994 • 16 citations

Reelin: A novel extracellular matrix protein involved in brain lamination

1995 • 11 citations

Distribution of mesencephalic trigeminal nucleus neurons in the reeler mutant mouse

1996 • 10 citations