Analysis of transport and targeting of syndecan-1: effect of cytoplasmic tail deletions.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

1987 • 4,937 citations

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

1991 • 2,437 citations

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

1991 • 1,507 citations

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1988 • 1,351 citations

Biology of the Syndecans: A Family of Transmembrane Heparan Sulfate Proteoglycans

1992 • 1,095 citations

Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes.

1986 • 847 citations

Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

1991 • 832 citations

Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA

1982 • 764 citations

Brefeldin A redistributes resident and itinerant Golgi proteins to the endoplasmic reticulum.

1989 • 581 citations

Molecular cloning of syndecan, an integral membrane proteoglycan.

1989 • 505 citations

Isolation and expression of an altered mouse dihydrofolate reductase cDNA.

1983 • 436 citations

Mechamisms of cell polarity: sorting and transport in epithelial cells

1994 • 430 citations

Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells.

1985 • 429 citations

Polarized sorting of viral glycoproteins to the axon and dendrites of hippocampal neurons in culture

1990 • 425 citations

A new cationic liposome reagent mediating nearly quantitative transfection of animal cells.

1991 • 390 citations

Expression of recombinant plasmids in mammalian cells Is enhanced by sodium butyrate

1983 • 380 citations

Cell surface proteoglycan binds mouse mammary epithelial cells to fibronectin and behaves as a receptor for interstitial matrix

1988 • 345 citations

Syndecan 4 heparan sulfate proteoglycan is a selectively enriched and widespread focal adhesion component.

1994 • 327 citations

Cell surface proteoglycan associates with the cytoskeleton at the basolateral cell surface of mouse mammary epithelial cells.

1986 • 314 citations

The cell surface proteoglycan from mouse mammary epithelial cells bears chondroitin sulfate and heparan sulfate glycosaminoglycans.

1985 • 301 citations

An autonomous signal for basolateral sorting in the cytoplasmic domain of the polymeric immunoglobulin receptor

1991 • 298 citations

Identification of a membrane-cytoskeletal complex containing the cell adhesion molecule uvomorulin (E-cadherin), ankyrin, and fodrin in Madin-Darby canine kidney epithelial cells.

1990 • 294 citations

Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin.

1985 • 286 citations

Heparan sulfate proteoglycans from mouse mammary epithelial cells. Cell surface proteoglycan as a receptor for interstitial collagens.

1985 • 284 citations

Ligand-affinity cloning and structure of a cell surface heparan sulfate proteoglycan that binds basic fibroblast growth factor.

1990 • 274 citations

Plasma membrane protein sorting in polarized epithelial cells.

1992 • 272 citations

Altered cytoplasmic domains affect intracellular transport of the vesicular stomatitis virus glycoprotein

1983 • 264 citations

Fc receptor isoforms exhibit distinct abilities for coated pit localization as a result of cytoplasmic domain heterogeneity

1989 • 259 citations

A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin.

1991 • 257 citations

Selective inhibition of transcytosis by brefeldin A in MDCK cells

1991 • 254 citations

A di-leucine motif mediates endocytosis and basolateral sorting of macrophage IgG Fc receptors in MDCK cells.

1994 • 253 citations

Immunocytochemistry of cell surface heparan sulfate proteoglycan in mouse tissues. A light and electron microscopic study.

1987 • 252 citations

Structural requirements and sequence motifs for polarized sorting and endocytosis of LDL and Fc receptors in MDCK cells.

1994 • 242 citations

Heparan sulfate-mediated binding of epithelial cell surface proteoglycan to thrombospondin

1989 • 222 citations

Syndecan from embryonic tooth mesenchyme binds tenascin.

1991 • 214 citations

Molecular cloning and characterization of N-syndecan, a novel transmembrane heparan sulfate proteoglycan

1992 • 198 citations

Basolateral to apical transcytosis in polarized cells is indirect and involves BFA and trimeric G protein sensitive passage through the apical endosome

1994 • 186 citations

Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody.

1985 • 185 citations

The hyaluronate receptor is associated with actin filaments.

1987 • 182 citations

Cell surface proteoglycan of mouse mammary epithelial cells is shed by cleavage of its matrix-binding ectodomain from its membrane-associated domain.

1987 • 170 citations

Common signals control low density lipoprotein receptor sorting in endosomes and the Golgi complex of MDCK cells

1993 • 167 citations

Molecular cloning of amphiglycan, a novel integral membrane heparan sulfate proteoglycan expressed by epithelial and fibroblastic cells.

1992 • 166 citations

Vesicular stomatitis virus glycoprotein contains a dominant cytoplasmic basolateral sorting signal critically dependent upon a tyrosine.

1993 • 160 citations

Ricin transport in brefeldin A-treated cells: correlation between Golgi structure and toxic effect.

1991 • 152 citations

Variations in the cytoskeletal interaction and posttranslational modification of the CD44 homing receptor in macrophages.

1991 • 146 citations

Binding of human syndecan to extracellular matrix proteins.

1990 • 143 citations

Fc receptor endocytosis is controlled by a cytoplasmic domain determinant that actively prevents coated pit localization.

1992 • 142 citations

The coordinated regulation of heparan sulfate, syndecans and cell behavior

1993 • 129 citations

The basolateral targeting signal in the cytoplasmic domain of glycoprotein G from vesicular stomatitis virus resembles a variety of intracellular targeting motifs related by primary sequence but having diverse targeting activities.

1994 • 127 citations

Mutations of the Rous sarcoma virus env gene that affect the transport and subcellular location of the glycoprotein products.

1984 • 109 citations

Differential expression of cell surface heparan sulfate proteoglycans in human mammary epithelial cells and lung fibroblasts.

1992 • 109 citations

The cytoplasmic tail of lysosomal acid phosphatase contains overlapping but distinct signals for basolateral sorting and rapid internalization in polarized MDCK cells.

1993 • 108 citations

Polarized sorting of the polymeric immunoglobulin receptor in the exocytotic and endocytotic pathways is controlled by the same amino acids.

1994 • 106 citations

Effects of brefeldin A on endocytosis, transcytosis and transport to the Golgi complex in polarized MDCK cells.

1992 • 105 citations

The cytoplasmic tail of CD44 is required for basolateral localization in epithelial MDCK cells but does not mediate association with the detergent-insoluble cytoskeleton of fibroblasts.

1993 • 104 citations

Molecular cloning of the major cell surface heparan sulfate proteoglycan from rat liver.

1992 • 100 citations

Syndecan-1 expressed in Schwann cells causes morphological transformation and cytoskeletal reorganization and associates with actin during cell spreading

1994 • 95 citations

A cell surface integral membrane glycoprotein of 85,000 mol wt (gp85) associated with triton X-100-insoluble cell skeleton.

1984 • 79 citations

Selective inhibition of protein targeting to the apical domain of MDCK cells by brefeldin A.

1992 • 74 citations

Clonal variation in cell surface display of an H-2 protein lacking a cytoplasmic tail.

1986 • 66 citations

Assay of proteoglycan populations using agarose-polyacrylamide gel electrophoresis

1985 • 66 citations

Differential effect of brefeldin A on the biosynthesis of heparan sulfate and chondroitin/dermatan sulfate proteoglycans in rat ovarian granulosa cells in culture

1993 • 62 citations

Differential expression of transmembrane proteoglycans in vascular smooth muscle cells.

1993 • 57 citations

Brefeldin A causes structural and functional alterations of the trans-Golgi network of MDCK cells

1994 • 56 citations

Regulated expression of syndecan in vascular smooth muscle cells and cloning of rat syndecan core protein cDNA.

1992 • 48 citations

Characteristics of the internalization signal in the Y543 influenza virus hemagglutinin suggest a model for recognition of internalization signals containing tyrosine.

1994 • 43 citations

Expression of amplified DNA sequences for ornithine transcarbamylase in HeLa cells: arginine residues may be required for mitochondrial import of enzyme precursor.

1985 • 37 citations

Brefeldin-A inhibits the delivery of the polymeric immunoglobulin receptor to the basolateral surface of MDCK cells.

1993 • 34 citations

The cytoplasmic domain of syndecan-1 is not required for association with Triton X-100-insoluble material

1994 • 32 citations

Polarized distribution of the viral glycoproteins of vesicular stomatitis, fowl plague and Semliki Forest viruses in hippocampal neurons in culture: a light and electron microscopic study

1993 • 24 citations

Electron-microscopic and electrophoretic studies of bovine femoral-head cartilage proteoglycan fractions

1986 • 16 citations