Ricin transport in brefeldin A-treated cells: correlation between Golgi structure and toxic effect.

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway

1990 • 972 citations

Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum.

1988 • 871 citations

Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes.

1986 • 847 citations

Establishment and characterization of a cell line of human breast carcinoma origin

1979 • 653 citations

Membrane flow during pinocytosis. A stereologic analysis.

1976 • 639 citations

Brefeldin A redistributes resident and itinerant Golgi proteins to the endoplasmic reticulum.

1989 • 581 citations

Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents.

1983 • 558 citations

Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae

1991 • 465 citations

Exit of newly synthesized membrane proteins from the trans cisterna of the Golgi complex to the plasma membrane.

1985 • 415 citations

Acidification of the cytosol inhibits endocytosis from coated pits.

1987 • 345 citations

Intracellular routing of transferrin and transferrin receptors in epidermoid carcinoma A431 cells

1983 • 330 citations

Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation

1989 • 317 citations

Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule.

1981 • 291 citations

Subcellular organization of glycosylation in mammalian cells

1987 • 271 citations

Immunolocalization of Kex2 protease identifies a putative late Golgi compartment in the yeast Saccharomyces cerevisiae.

1991 • 268 citations

The Ways of Endocytosis

1989 • 237 citations

Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles.

1982 • 234 citations

Routing of internalized ricin and ricin conjugates to the Golgi complex.

1986 • 231 citations

Compartmentation of the Golgi complex: brefeldin-A distinguishes trans-Golgi cisternae from the trans-Golgi network.

1990 • 222 citations

Estimation of the amount of internalized ricin that reaches the trans-Golgi network

1988 • 212 citations

The dynamic nature of the Golgi complex.

1989 • 210 citations

Differential subcompartmentation of terminal glycosylation in the Golgi apparatus of intestinal absorptive and goblet cells.

1986 • 172 citations

Proteolytic Processing of Pro-ACTH/Endorphin Begins in the Golgi Complex of Pituitary Corticotropes and AtT-20 Cells

1989 • 165 citations

Disruption of the Golgi apparatus by brefeldin A inhibits the cytotoxicity of ricin, modeccin, and Pseudomonas toxin

1991 • 156 citations

Selective modulation of the endocytic uptake of ricin and fluid phase markers without alteration in transferrin endocytosis.

1990 • 145 citations

A polarized epithelial cell mutant deficient in translocation of UDP-galactose into the Golgi complex.

1988 • 136 citations

How protein toxins enter and kill cells

1988 • 122 citations

Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells

1979 • 120 citations

Targeting and processing of glycophorins in murine erythroleukemia cells: use of brefeldin A as a perturbant of intracellular traffic.

1989 • 104 citations

Endocytosis and intracellular transport of the glycolipid-binding ligand Shiga toxin in polarized MDCK cells.

1991 • 87 citations

Delivery of internalized ricin from endosomes to cisternal golgi elements is a discontinuous, temperature-sensitive process

1987 • 74 citations

Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments.

1984 • 71 citations

A method for rapid isolation of rough and smooth microsomes and golgi apparatus from rat liver in the same sucrose gradient

1980 • 67 citations

Endocytosis, intracellular transport and transcytosis of the toxic protein ricin by a polarized epithelium.

1990 • 61 citations

Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin.

1986 • 49 citations

Prosomatostatin is processed in the Golgi apparatus of rat neural cells

1991 • 49 citations

Dynamic distribution of the Golgi marker thiamine pyrophosphatase is modulated by brefeldin A in rat hepatoma cells.

1989 • 47 citations

Inhibition of endocytosis from coated pits by acidification of the cytosol

1988 • 45 citations

Increased cytotoxicity of ricin in a putative Golgi-defective mutant of Chinese hamster ovary cell

1990 • 33 citations

Differential effects of brefeldin A on sialylation of N- and O-linked oligosaccharides in low density lipoprotein receptor and epidermal growth factor receptor.

1990 • 32 citations

Morphological effects of Brefeldin A on the intracellular transport of secretory materials in parotid acinar cells.

1990 • 24 citations

Intracellular accumulation and oligosaccharide processing of alkaline phosphatase under disassembly of the Golgi complex caused by brefeldin A

1990 • 19 citations

Chapter 16 Control of Coated-Pit Function by Cytoplasmic pH

1989 • 18 citations

Rapid turnover of low‐density lipoprotein receptor by a non‐lysosomal pathway in mouse macrophage J774 cells and inhibitory effect of brefeldin A

1990 • 14 citations