Oral Fingolimod (FTY720) for Relapsing Multiple Sclerosis

Rating neurologic impairment in multiple sclerosis

1983 • 14,011 citations

World Medical Association Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects

2003 • 10,838 citations

Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis

2001 • 6,888 citations

Axonal Transection in the Lesions of Multiple Sclerosis

1998 • 4,007 citations

Multiple Sclerosis

2000 • 2,813 citations

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

2004 • 2,462 citations

Intramuscular interferon beta‐1a for disease progression in relapsing multiple sclerosis

1996 • 2,410 citations

IMMUNOLOGY OF MULTIPLE SCLEROSIS

2005 • 2,099 citations

Randomised double-blind placebo-controlled study of interferon β-1a in relapsing/remitting multiple sclerosis

1998 • 2,049 citations

Accurate, Robust, and Automated Longitudinal and Cross-Sectional Brain Change Analysis

2002 • 1,962 citations

Copolymer 1 reduces relapse rate and improves disability in relapsing‐remitting multiple sclerosis

1995 • 1,903 citations

Multiple sclerosis

2002 • 1,678 citations

Generalized Estimating Equations

2002 • 1,673 citations

Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists

2002 • 1,655 citations

The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors

2002 • 1,478 citations

Interferon beta‐lb in the treatment of multiple sclerosis

1995 • 899 citations

Disease modifying therapies in multiple sclerosis: Subcommittee of the American Academy of Neurology and the MS Council for Clinical Practice Guidelines: Table 1.

2002 • 812 citations

FTY720: Sphingosine 1-Phosphate Receptor-1 in the Control of Lymphocyte Egress and Endothelial Barrier Function

2004 • 462 citations

Magnetic resonance imaging in monitoring the treatment of multiple sclerosis: concerted action guidelines.

1991 • 373 citations

FTY720 Immunosuppression Impairs Effector T Cell Peripheral Homing Without Affecting Induction, Expansion, and Memory

2000 • 364 citations

Neuroimaging in Posterior Reversible Encephalopathy Syndrome

2004 • 352 citations

Reversible posterior leukoencephalopathy syndrome: a misnomer reviewed

2005 • 300 citations

Amelioration of Experimental Autoimmune Encephalomyelitis in Lewis Rats by FTY720 Treatment

2003 • 281 citations

Sphingosine 1-phosphate receptor agonists attenuate relapsing–remitting experimental autoimmune encephalitis in SJL mice

2004 • 221 citations

FTY720, A Novel Immunomodulator: Efficacy and Safety Results from the First Phase 2A Study in de novo Renal Transplantation

2004 • 216 citations

Differential transactivation of sphingosine-1-phosphate receptors modulates NGF-induced neurite extension

2004 • 169 citations

The Heart Rate Decrease Caused by Acute FTY720 Administration Is Mediated by the G Protein-Gated Potassium Channel IKACh

2005 • 162 citations

Fluvastatin Prevents Cardiac Death and Myocardial Infarction in Renal Transplant Recipients: Post-Hoc Subgroup Analyses of the ALERT Study

2004 • 122 citations

Characterization of lysophosphatidic acid and sphingosine‐1‐phosphate‐mediated signal transduction in rat cortical oligodendrocytes

2003 • 121 citations

Microglial activation state and lysophospholipid acid receptor expression

2003 • 117 citations

The role of MRI as a surrogate outcome measure in multiple sclerosis

2002 • 104 citations

Magnetic resonance imaging in monitoring the treatment of multiple sclerosis patients: Statistical power of parallel-groups and crossover designs

1994 • 95 citations

Pharmacological characterization of lysophospholipid receptor signal transduction pathways in rat cerebrocortical astrocytes

2003 • 94 citations

US FDA-Approved Disease-Modifying Treatments for Multiple Sclerosis

2005 • 69 citations

Considerations in the treatment of relapsing-remitting multiple sclerosis

2002 • 56 citations

Hospital Clínico San Carlos.

2000 • 36 citations

FTY720, A SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONIST, HAS NO ADVERSE EFFECTS ON CARDIAC CONDUCTION OR RHYTHM IN MAINTENANCE RENAL TRANSPLANT PATIENTS

2004 • 3 citations