Matrix Metalloproteinases Generate Angiostatin: Effects on Neovascularization

Endostatin: An Endogenous Inhibitor of Angiogenesis and Tumor Growth

1997 • 4,504 citations

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

1994 • 3,367 citations

Requirement of Vascular Integrin α _v β ₃ for Angiogenesis

1994 • 3,016 citations

Matrix Metalloproteinases: A Review

1993 • 2,998 citations

Induction of angiogenesis during the transition from hyperplasia to neoplasia

1989 • 1,912 citations

Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression

1995 • 1,863 citations

Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures.

1988 • 1,209 citations

Processing of tumour necrosis factor-α precursor by metalloproteinases

1994 • 1,200 citations

Macrophages and angiogenesis

1994 • 1,123 citations

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin.

1990 • 1,062 citations

Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation

1997 • 664 citations

The Matrix Metalloproteinases and Their Inhibitors

1992 • 604 citations

Tissue cooperation in a proteolytic cascade activating human interstitial collagenase.

1989 • 579 citations

Macrophage-Derived Metalloelastase Is Responsible for the Generation of Angiostatin in Lewis Lung Carcinoma

1997 • 537 citations

Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice.

1996 • 496 citations

Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages.

1993 • 479 citations

Angiostatin-converting Enzyme Activities of Human Matrilysin (MMP-7) and Gelatinase B/Type IV Collagenase (MMP-9)

1997 • 430 citations

Human skin collagenase: isolation of precursor and active forms from both fibroblast and organ cultures

1977 • 387 citations

Kringle Domains of Human Angiostatin

1996 • 366 citations

Induction of neovascularization in vivo and endothelial proliferation in vitro by tumor-associated macrophages.

1984 • 366 citations

Hydrolysis of a Broad Spectrum of Extracellular Matrix Proteins by Human Macrophage Elastase

1997 • 313 citations

Kringle 5 of Plasminogen is a Novel Inhibitor of Endothelial Cell Growth

1997 • 294 citations

The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin

1997 • 292 citations

Primary structure and cDNA cloning of human fibroblast collagenase inhibitor.

1986 • 274 citations

Mouse macrophage elastase. Purification and characterization as a metalloproteinase

1981 • 260 citations

The Structural Basis for the Elastolytic Activity of the 92-kDa and 72-kDa Gelatinases

1996 • 216 citations

Human prostate carcinoma cells express enzymatic activity that converts human plasminogen to the angiogenesis inhibitor, angiostatin.

1996 • 199 citations

Molecular cloning, chromosomal localization, and bacterial expression of a murine macrophage metalloelastase.

1992 • 197 citations

Progress in Cancer Research and Therapy.

1978 • 195 citations

Alpha 1-proteinase inhibitor is a neutrophil chemoattractant after proteolytic inactivation by macrophage elastase.

1988 • 170 citations

Generation of Angiostatin by Reduction and Proteolysis of Plasmin

1997 • 161 citations

Basic Fibroblast Growth Factor Increases Expression of the αvβ3 Integrin Complex on Human Microvascular Endothelial Cells

1994 • 140 citations

Complex Roles of Matrix Metalloproteinases in Tumor Progression

1996 • 121 citations

Purification of human collagenases with a hydroxamic acid affinity column

1986 • 114 citations

GROWTH OF A LOCAL TUMOR EXERTS A SPECIFIC INHIBITORY EFFECT ON PROGRESSION OF LUNG METASTASES

1978 • 96 citations

Spectrophotometric assay for vertebrate collagenase

1985 • 91 citations

Contribution of the C-terminal domain of metalloproteinases to binding by tissue inhibitor of metalloproteinases. C-terminal truncated stromelysin and matrilysin exhibit equally compromised binding affinities as compared to full-length stromelysin.

1994 • 75 citations

Mechanism of the induction of angiogenesis by human neoplastic lymphoid tissue: Studies on the chorioallantoic membrane (CAM) of the chick embryo

1980 • 51 citations

High Level, Stable Production of Recombinant Proteins in Mammalian Cell Culture using the Herpesvirus VP16 Transactivator

1993 • 30 citations

Tumor angiogenesis: Functional similarities with tumor invasion

1997 • 24 citations