Young Age at Diagnosis Correlates With Worse Prognosis and Defines a Subset of Breast Cancers With Shared Patterns of Gene Expression

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

2005 • 44,461 citations

Molecular portraits of human breast tumours

2000 • 15,445 citations

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

2001 • 10,602 citations

Gene expression profiling predicts clinical outcome of breast cancer

2002 • 9,314 citations

Regression Modeling Strategies

2001 • 8,706 citations

A Gene-Expression Signature as a Predictor of Survival in Breast Cancer

2002 • 6,428 citations

A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer

2004 • 5,895 citations

Repeated observation of breast tumor subtypes in independent gene expression data sets

2003 • 5,356 citations

Triple-Negative Breast Cancer: Clinical Features and Patterns of Recurrence

2007 • 4,498 citations

Race, Breast Cancer Subtypes, and Survival in the Carolina Breast Cancer Study

2006 • 3,623 citations

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

2005 • 2,658 citations

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

2005 • 2,015 citations

Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene

1985 • 1,804 citations

Concordance among Gene-Expression–Based Predictors for Breast Cancer

2006 • 1,336 citations

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

2005 • 1,225 citations

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival

2005 • 956 citations

Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds

2004 • 931 citations

The Product of the Human c- erb B-2 Gene: a 185-Kilodalton Glycoprotein with Tyrosine Kinase Activity

1986 • 805 citations

Genetic Reclassification of Histologic Grade Delineates New Clinical Subtypes of Breast Cancer

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Genomic signatures to guide the use of chemotherapeutics

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Relationship of patient age to pathologic features of the tumor and prognosis for patients with stage I or II breast cancer.

1994 • 573 citations

The Relation between Survival and Age at Diagnosis in Breast Cancer

1986 • 530 citations

Age as prognostic factor in premenopausal breast carcinoma

1993 • 482 citations

BRCA1Mutations in a Population-Based Sample of Young Women with Breast Cancer

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Is chemotherapy alone adequate for young women with oestrogen-receptor-positive breast cancer?

2000 • 288 citations

Breast cancer outcome and predictors of outcome: are there age differentials?

1994 • 268 citations

Effects of young age at presentation on survival in breast cancer

2006 • 253 citations

Poor Outcome of Hormone Receptor–Positive Breast Cancer at Very Young Age Is Due to Tamoxifen Resistance: Nationwide Survival Data in Korea—A Report From the Korean Breast Cancer Society

2007 • 249 citations

BRCA1 Mutations and Breast Cancer in the General Population

1998 • 248 citations

Differential prognostic impact of hypoxia induced and diffuse HIF-1 expression in invasive breast cancer

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Early-onset breast cancer – histopathological and prognostic considerations

1997 • 212 citations

Determination of oestrogen-receptor status and ERBB2 status of breast carcinoma: a gene-expression profiling study

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The molecular pathology of hereditary breast cancer: genetic testing and therapeutic implications

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Ordinal Logistic Regression

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12. Management of Menopausal Symptoms

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Therapeutic Implications of the Cancer Stem Cell Hypothesis

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Intron 3 16 bp duplication polymorphism of p53 is associated with an increased risk for breast cancer by the age of 50 years

2002 • 85 citations

Effect of age on the survival of breast cancer patients

1997 • 80 citations

C-erbB-2 overexpression and survival in early onset breast cancer

2000 • 68 citations

Differential Expression of Prognostic Factors and Effect on Survival in Young (≤40) Breast Cancer Patients: A Case-Control Study

2006 • 61 citations