The Product of the Human c- erb B-2 Gene: a 185-Kilodalton Glycoprotein with Tyrosine Kinase Activity

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1980 • 2,387 citations

Agricultural and biological chemistry

1961 • 1,291 citations

Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor

1986 • 1,226 citations

The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

1984 • 1,153 citations

The neu oncogene encodes an epidermal growth factor receptor-related protein

1986 • 1,131 citations

Amplification of a Novel v- erb B-Related Gene in a Human Mammary Carcinoma

1985 • 1,064 citations

Tunicamycin inhibition of polyisoprenyl N-acetylglucosaminyl pyrophosphate formation in calf-liver microsomes

1975 • 863 citations

Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody.

1983 • 792 citations

Autophosphorylation sites on the epidermal growth factor receptor

1984 • 730 citations

Clonal cell lines from the rat central nervous system

1974 • 727 citations

Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells

1981 • 669 citations

A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma.

1985 • 607 citations

Viral oncogenes

1985 • 605 citations

Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro

1978 • 448 citations

The erbB gene of avian erythroblastosis virus is a member of the src gene family

1983 • 377 citations

Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line.

1986 • 329 citations

Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbb protein

1985 • 310 citations

Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells

1984 • 296 citations

Transforming capacities of avian erythroblastosis virus mutants deleted in the erbA or erbB oncogenes

1983 • 296 citations

Glycosylation of the epidermal growth factor receptor in A-431 cells. The contribution of carbohydrate to receptor function.

1984 • 229 citations

Inhibition of Biosynthesis of Polyisoprenol Sugars in Chick Embryo Microsomes by Tunicamycin

1975 • 218 citations

A v-erbB-related protooncogene, c-erb-B-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma

1985 • 195 citations

Oncogenes and growth control

1985 • 180 citations

Identification and characterization of the avian erythroblastosis virus erbB gene product as a membrane glycoprotein

1983 • 167 citations

A new avian erythroblastosis virus, AEV-H, carries erbB gene responsible for the induction of both erythroblastosis and sarcomas

1983 • 137 citations

Site-specific mutagenesis of avian erythroblastosis virus: erb-B is required for oncogenicity

1983 • 127 citations

Post-translational processing of the epidermal growth factor receptor. Glycosylation-dependent acquisition of ligand-binding capacity.

1985 • 119 citations

The product of the avian erythroblastosis virus erbB locus is a glycoprotein

1983 • 111 citations

Identification of a form of the avian erythroblastosis virus erb-B gene product at the cell surface

1984 • 86 citations

Phosphorylation of the erbB gene product from an avian erythroblastosis virus-transformed chick fibroblast cell line.

1985 • 50 citations

Characterization of the epidermal growth factor receptor and the erbB oncogene product by site-specific antibodies

1986 • 11 citations

Site-specific antibodies to the oncogene produc immunoprecipitate epidermal growth factor receptor

1984 • 7 citations