Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

1995 • 9,575 citations

PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

2003 • 8,996 citations

Nonparametric Statistical Methods

1999 • 6,387 citations

Expression monitoring by hybridization to high-density oligonucleotide arrays

1996 • 2,796 citations

Nonparametric Statistical Methods.

1974 • 2,779 citations

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

2001 • 2,560 citations

Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes

2004 • 2,151 citations

Gene-expression profiles predict survival of patients with lung adenocarcinoma

2002 • 2,005 citations

Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals

2005 • 1,895 citations

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

2003 • 1,893 citations

Identifying differentially expressed genes using false discovery rate controlling procedures

2003 • 1,741 citations

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

2001 • 1,672 citations

Diversity of gene expression in adenocarcinoma of the lung

2001 • 1,299 citations

The IARC TP53 database: New online mutation analysis and recommendations to users

2002 • 1,248 citations

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

2004 • 951 citations

MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data

2003 • 865 citations

Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

2004 • 799 citations

Cytogenetics in acute leukemia

2003 • 652 citations

Mathematical Theory of Probability and Statistics

1964 • 639 citations

Characterizing gene sets with FuncAssociate

2003 • 473 citations

Xist RNA and the Mechanism of X Chromosome Inactivation

2002 • 438 citations

Telomerase modulates expression of growth-controlling genes and enhances cell proliferation

2003 • 435 citations

A Mechanism of Cyclin D1 Action Encoded in the Patterns of Gene Expression in Human Cancer

2003 • 421 citations

An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis

2004 • 420 citations

The Immunosuppressant Rapamycin Mimics a Starvation-Like Signal Distinct from Amino Acid and Glucose Deprivation

2002 • 394 citations

A first-generation X-inactivation profile of the human X chromosome

1999 • 362 citations

Mathematical Theory of Probability and Statistics

1966 • 188 citations

Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1–1.5 Mb and preparation of a PAC-based physical map

1997 • 154 citations

GoSurfer

2004 • 119 citations

Escape from X inactivation

2002 • 111 citations

Rapamycin Inhibits the Growth and Metastatic Progression of Non-Small Cell Lung Cancer

2004 • 106 citations

A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology

2002 • 93 citations

A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease progression of chronic myeloid leukemia and forms a fusion gene with HOXA9 as a result of the cryptic t(7;17)(p15;q23).

2003 • 91 citations

Cloning and characterization of the common fragile site FRA6F harboring a replicative senescence gene and frequently deleted in human tumors

2002 • 85 citations

Frequent allelic loss of the RB, D13S319 and D13S25 locus in myeloid malignancies with deletion/translocation at 13q14 of chromosome 13, but not in lymphoid malignancies

1999 • 23 citations