The Cysteine-Rich Sprouty Translocation Domain Targets Mitogen-Activated Protein Kinase Inhibitory Proteins to Phosphatidylinositol 4,5-Bisphosphate in Plasma Membranes

Visualization of Phosphoinositides That Bind Pleckstrin Homology Domains: Calcium- and Agonist-induced Dynamic Changes and Relationship to Myo-[3H]inositol-labeled Phosphoinositide Pools

1998 • 820 citations

Phosphatidylinositol 4-Phosphate 5-Kinase α Is a Downstream Effector of the Small G Protein ARF6 in Membrane Ruffle Formation

1999 • 800 citations

sprouty Encodes a Novel Antagonist of FGF Signaling that Patterns Apical Branching of the Drosophila Airways

1998 • 745 citations

Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells

1998 • 733 citations

Phosphatidylinositol 4,5-Bisphosphate Functions as a Second Messenger that Regulates Cytoskeleton–Plasma Membrane Adhesion

2000 • 651 citations

Rac Homologues and Compartmentalized Phosphatidylinositol 4, 5-Bisphosphate Act in a Common Pathway to Regulate Polar Pollen Tube Growth

1999 • 566 citations

Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed

1999 • 503 citations

Role of the ENTH Domain in Phosphatidylinositol-4,5-Bisphosphate Binding and Endocytosis

2001 • 466 citations

Spred is a Sprouty-related suppressor of Ras signalling

2001 • 429 citations

Specificity and Promiscuity in Phosphoinositide Binding by Pleckstrin Homology Domains

1998 • 426 citations

Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D

2001 • 369 citations

Green Fluorescent Protein (GFP)-tagged Cysteine-rich Domains from Protein Kinase C as Fluorescent Indicators for Diacylglycerol Signaling in Living Cells

1998 • 331 citations

The Recruitment of Raf-1 to Membranes Is Mediated by Direct Interaction with Phosphatidic Acid and Is Independent of Association with Ras

2000 • 307 citations

Mammalian Sprouty-1 and -2 Are Membrane-Anchored Phosphoprotein Inhibitors of Growth Factor Signaling in Endothelial Cells

2001 • 275 citations

The synthesis and cellular roles of phosphatidylinositol 4,5-bisphosphate

1998 • 267 citations

Aluminum fluoride stimulates surface protrusions in cells overexpressing the ARF6 GTPase.

1996 • 237 citations

The essential role of profilin in the assembly of actin for microspike formation

1998 • 237 citations

Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly

2000 • 230 citations

Sprouty2 Inhibits the Ras/MAP Kinase Pathway by Inhibiting the Activation of Raf

2002 • 224 citations

sprouty4acts in vivo as a feedback-induced antagonist of FGF signaling in zebrafish

2001 • 215 citations

Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis

2001 • 211 citations

Phosphoinositide Binding Domains

1999 • 130 citations

The Phox homology (PX) domain, a new player in phosphoinositide signalling

2001 • 128 citations

Evidence for Direct Interaction between Sprouty and Cbl

2001 • 127 citations

Dynamics of phosphatidylinositol 4,5-bisphosphate in actin-rich structures

2000 • 119 citations

The C Terminus of Sprouty Is Important for Modulation of Cellular Migration and Proliferation

2001 • 103 citations

Sprouty Proteins Are Targeted to Membrane Ruffles upon Growth Factor Receptor Tyrosine Kinase Activation

2000 • 98 citations

Structural properties of lipid-binding sites in cytoskeletal proteins

2001 • 95 citations

DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides

1999 • 95 citations

The Phox homology (PX) domain, a new player in phosphoinositide signalling

2001 • 90 citations

Progress in protrusion: the tell-tale scar

1999 • 69 citations

Real-Time Visualization of PH Domain-Dependent Translocation of Phospholipase C-δ1 in Renal Epithelial Cells (MDCK): Response to Hypo-osmotic Stress

1999 • 55 citations

Distinct roles of profilin in cell morphological changes: microspikes, membrane ruffles, stress fibers, and cytokinesis

1999 • 46 citations

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