The expression of several T cell-specific and novel genes is repressed by trans-acting factors in immature T lymphoma clones.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1984 • 1,239 citations

The T Cell Receptor/CD3 Complex: A Dynamic Protein Ensemble

1988 • 786 citations

Molecular and Cellular Events of T Cell Development

1989 • 466 citations

Differentiation-Linked Leukemogenesis in Lymphocytes

1986 • 359 citations

Tumors as caricatures of the process of tissue renewal: prospects for therapy by directing differentiation.

1988 • 357 citations

Production of mRNA in chinese hamster cells: Relationship of the rate of synthesis to the cytoplasmic concentration of nine specific mRNA sequences

1979 • 326 citations

Molecular Cloning of the Zeta Chain of the T Cell Antigen Receptor

1988 • 275 citations

Colocalized transmembrane determinants for ER degradation and subunit assembly explain the intracellular fate of TCR chains

1990 • 266 citations

Early Events in T-Cell Maturation

1987 • 242 citations

Developmentally regulated rearrangement and expression of genes encoding the T cell receptor-T3 complex

1986 • 210 citations

A murine early thymocyte developmental sequence is marked by transient expression of the interleukin 2 receptor.

1989 • 185 citations

αβ lineage-specific expression of the α T cell receptor gene by nearby silencers

1989 • 182 citations

Differentiation potential of subsets of CD4−8− thymocytes

1987 • 169 citations

Nucleotide sequence and expression of a mouse interleukin 2 receptor cDNA.

1985 • 162 citations

Monoclonal antibody to L3T4 blocks the function of T cells specific for class 2 major histocompatibility complex antigens.

1984 • 140 citations

A transcriptional repressor of c-myc

1989 • 129 citations

T-cell receptor gamma delta and gamma transgenic mice suggest a role of a gamma gene silencer in the generation of alpha beta T cells.

1990 • 128 citations

Unusual intron in the immunoglobulin domain of the newly isolated murine CD4 (L3T4) gene

1987 • 127 citations

Thymus cell maturation

1975 • 127 citations

Importance of IL-2 receptors in intra-thymic generation of cells expressing T-cell receptors

1987 • 124 citations

The expression of T cell receptor-associated proteins during T cell ontogeny in man.

1989 • 122 citations

T cell receptor-CD3 complex during early T cell differentiation. Analysis of immature T cell acute lymphoblastic leukemias (T-ALL) at DNA, RNA, and cell membrane level.

1987 • 118 citations

A developmental-specific factor binds to suppressor sites flanking the immunoglobulin heavy-chain enhancer.

1989 • 116 citations

Transient expression of IL-2 receptor precedes the differentiation of immature thymocytes

1987 • 112 citations

A labile inhibitor blocks immunoglobulin kappa-light-chain-gene transcription in a pre-B leukemic cell line.

1986 • 109 citations

Evolutionary relationship between the T3 chains of the T-cell receptor complex and the immunoglobulin supergene family.

1987 • 107 citations

Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions.

1985 • 101 citations

Mechanisms that Regulate Immunoglobulin Gene Expression

1985 • 97 citations

Essential role of the interleukin 2-interleukin 2 receptor pathway in thymocyte maturation in vivo.

1988 • 95 citations

CD3-negative lymphokine-activated cytotoxic cells express the CD3 epsilon gene.

1988 • 94 citations

Epidermal growth factor regulates the in vitro sensitivity of human ovarian carcinoma cells to cisplatin.

1990 • 89 citations

Isolation and characterization of a cDNA clone encoding the murine homologue of the human 20K T3/T-cell receptor glycoprotein

1985 • 86 citations

Activated T cells express a novel gene on chromosome 8 that is closely related to the murine ecotropic retroviral receptor.

1990 • 85 citations

Role of the octamer motif in hybrid cell extinction of immunoglobulin gene expression: Extinction is dominant in a two enhancer system

1989 • 82 citations

A novel oncofetal gene is expressed in a stage-specific manner in murine embryonic development

1990 • 74 citations

Thymocyte subpopulation enriched for progenitors with an unrearranged T-cell receptor β-chain gene

1985 • 72 citations

Molecular cloning of the cDNA encoding the T3 gamma subunit of the mouse T3/T cell antigen receptor complex.

1987 • 57 citations

T-cell-specific expression of interleukin 2: evidence for a negative regulatory site.

1988 • 57 citations

Thymocyte subpopulations during early fetal development in the BALB/c mouse.

1988 • 53 citations

Extinction of Ig genes expression in myeloma x fibroblast somatic cell hybrids is accompanied by repression of the oct-2 gene encoding a B-cell specific transcription factor.

1990 • 49 citations

Remethylation at sites 5' of the murine Lyt-2 gene in association with shutdown of Lyt-2 expression.

1988 • 42 citations

Induction of T-cell receptor-alpha and -beta mRNA in SL12 cells can occur by transcriptional and post-transcriptional mechanisms.

1988 • 41 citations

Sequence analysis and expression of an X-linked, lymphocyte-regulated gene family (XLR).

1987 • 40 citations

A rapid and convenient method for isolation of nuclear, cytoplasmic and total cellular RNA

1988 • 37 citations

The Physiology of B Cells as Studied with Tumor Models

1986 • 32 citations

A new murine model system for the in vitro development of thymoma cell heterogeneity.

1984 • 30 citations

Negative trans-regulation of T-cell antigen receptor/T3 complex mRNA expression in murine T-lymphoma somatic cell hybrids.

1986 • 27 citations

Isolation of novel complementary DNA clones from T lymphoma cells: one encodes a putative multiple membrane-spanning protein.

1990 • 22 citations

Activated T Cells Express a Novel Gene on Chromosome 8 That Is Closely Related to the Murine Ecotropic Retroviral Receptor

1990 • 20 citations

Tumorigenicity of T lymphoma/T lymphoma hybrids and T lymphoma/normal cell hybrids

1986 • 19 citations

SL 12 Murine T -Lymphoma: A New Model for Tumor Cell Heterogeneity<xref ref-type="fn" rid="FN1">2</xref>

1985 • 18 citations

A trans-acting mechanism represses the expression of the major transplantation antigens in mouse hybrid thymoma cell lines.

1986 • 18 citations

Early Events In T-Cell Maturation

1987 • 16 citations

Thymocyte clones from 14‐day mouse embryos II. Transcription of T3γ gene may precede rearrangement of TcRδ and expression of T3δ, T3_ε and T11 genes

1988 • 15 citations

Complex regulation of the T cell receptor α gene: three different modes of triggering induction

1988 • 14 citations

Genetic complexity of glucocorticoid-induced lysis of murine T-lymphoma cells.

1985 • 13 citations

The CD3δ gene encodes multiple transcripts regulated by transcriptional and post‐transcriptional mechanisms

1989 • 13 citations

Regulation of Thy-1 and Pgp-1 glycoproteins in hybrids between T-cell lymphomas and Abelson-leukemia-virus-induced lymphomas

1984 • 11 citations

Mechanisms that Regulate Immunoglobulin Gene Expression

1985 • 10 citations

Efficient transfer of DNA to nylon membranes using vacuum blotting in presence of alkali.

1989 • 10 citations

Trans-acting regulatory factors for T cell antigen receptor alpha- and gamma-chain gene expression.

1988 • 9 citations

A model system for T-lymphocyte differentiation: Regulation of CD4 and CD8 gene expression in SL12.4 T-lymphoma cell clones

1991 • 4 citations

Induction of T cell receptor γ chain transcription in murine T cells by trans‐complementation

1988 • 2 citations

The Physiology of B Cells as Studied with Tumor Models

1986 • 1 citations