Possible improved survival of patients with stage IV AJCC melanoma receiving SRL 172 immunotherapy: Correlation with induction of increased levels of intracellular interkukin-2 in peripheral blood lymphocytes

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape

1996 • 1,281 citations

Tumor Rejection After Direct Costimulation of CD8 ⁺ T Cells by B7-Transfected Melanoma Cells

1993 • 1,154 citations

A Randomized Trial of Intravesical Doxorubicin and Immunotherapy with Bacille Calmette–Guérin for Transitional-Cell Carcinoma of the Bladder

1991 • 605 citations

Heat shock proteins transfer peptides during antigen processing and CTL priming

1994 • 580 citations

BCG lmmunotherapy of Malignant Melanoma

1974 • 430 citations

Immunotherapy of Cancer: Present Status of Trials in Man

1977 • 212 citations

Inhibition of an established allergic response to ovalbumin in BALB/c mice by killed Mycobacterium vaccae

1998 • 207 citations

Local expression of antiinflammatory cytokines in cancer.

1993 • 198 citations

Interferon alfa-2a and interleukin-2 with or without cisplatin in metastatic melanoma: a randomized trial of the European Organization for Research and Treatment of Cancer Melanoma Cooperative Group.

1997 • 197 citations

Disregulation in TH1 and TH2 subsets of CD4 + T cells in peripheral blood of colorectal cancer patients and involvement in cancer establishment and progression

1996 • 194 citations

Urinary Cytokines During Intravesical Bacillus Calmetteguerin Therapy for Superficial Bladder Cancer: Processing, Stability and Prognostic Value

1996 • 185 citations

Bacillus Calmette-Guerin Versus Doxorubicin Versus Thiotepa: A Randomized Prospective Study in 202 Patients with Superficial Bladder Cancer

1990 • 179 citations

A Pathogenic Role of Th2 Cells and Their Cytokine Products on the Pulmonary Metastasis of Murine B16 Melanoma

1998 • 166 citations

Interleukin 2 production in vitro by peripheral lymphocytes in response to human papillomavirus-derived peptides: correlation with cervical pathology.

1996 • 153 citations

Induction of a type 1 immune response to a recombinant antigen from Mycobacterium tuberculosis expressed in Mycobacterium vaccae

1997 • 128 citations

Cancer vaccines: the interleukin 2 dosage effect.

1995 • 127 citations

Gradual Loss of T-Helper 1 Populations in Spleen of Mice During Progressive Tumor Growth

1995 • 117 citations

Prediction of response to treatment in superficial bladder carcinoma through pattern of interleukin-2 gene expression.

1996 • 98 citations

Immunization with heat-killed Mycobacterium vaccae stimulates CD8+ cytotoxic T cells specific for macrophages infected with Mycobacterium tuberculosis

1997 • 93 citations

Immunotherapy of advanced prostate cancer: a phase I/II trial using Mycobacterium vaccae (SRL172)

1998 • 86 citations

Regulation of Immune Responses by T Cells with Different Cytokine Secretion Phenotypes: Role of a New Cytokine, Cytokine Synthesis Inhibitory Factor (IL10)

1991 • 65 citations

Chemotherapy for malignant melanoma: combinations and high doses produce more responses without survival benefit

1990 • 61 citations

Tuberculosis and cancer: parallels in host responses and therapeutic approaches?

1995 • 59 citations

Abnormal intracellular IL-2 and interferon-gamma (IFN-γ) production as HIV-1-associated markers of immune dysfunction

1998 • 51 citations

Approaches to Augmenting the IgG Antibody Response to Melanoma Ganglioside Vaccines

1993 • 35 citations

Importance of Lyt 1+ T-cells in the antitumor activity of an immunomodulator, SSM, extracted from human-type Tubercle bacilli.

1986 • 31 citations

Down-regulation by interleukin 4 of activation of human alveolar macrophages to the tumoricidal state.

1991 • 28 citations

Immunoregulatory effects of CD4+ T helper subsets in human melanoma

1995 • 27 citations

Serologic response to human melanoma lines from patients with melanoma undergoing treatment with vaccinia melanoma oncolysates.

1984 • 26 citations

Immunotherapy of human melanomas and sarcomas.

1972 • 19 citations

Decreased interleukin-2 β-chain receptor expression by interleukin-4 on LGL: influence on the IL-2 induced cytotoxicity and proliferation

1992 • 7 citations