Asparagine 212 is essential for abasic site recognition by the human DNA repair endonuclease HAP1

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Instability and decay of the primary structure of DNA

1993 • 5,370 citations

REPAIR OF OXIDATIVE DAMAGE TO DNA: Enzymology and Biology

1994 • 1,435 citations

A general two-metal-ion mechanism for catalytic RNA.

1993 • 1,125 citations

Structural basis for the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism.

1991 • 1,059 citations

Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme.

1992 • 920 citations

MUTAGENESIS BY APURINIC/APYRIMIDINIC SITES

1986 • 884 citations

A general method for rapid site-directed mutagenesis using the polymerase chain reaction

1990 • 642 citations

Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes.

1991 • 526 citations

Structure and function of the multifunctional DNA-repair enzyme exonuclease III

1995 • 382 citations

The enzymology of apurinic/apyrimidinic endonucleases

1990 • 378 citations

Structure of DNase I at 2.0 Å resolution suggests a mechanism for binding to and cutting DNA

1986 • 327 citations

Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects inE.coli xth(exonuclease III) mutants

1991 • 294 citations

Structure refined to 2Å of a nicked DNA octanucleotide complex with DNase I

1988 • 293 citations

The 3′-5′ exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction.

1991 • 279 citations

Crystal structure of Penicillium citrinum P1 nuclease at 2.8 A resolution.

1991 • 256 citations

Ap endonucleases and dna glycosylases that recognize oxidative dna damage

1988 • 254 citations

Structure and function of apurinic/apyrimidinic endonucleases

1995 • 205 citations

Identification of critical active-site residues in the multifunctional human DNA repair enzyme HAP1

1995 • 130 citations

Site-directed mutagenesis of the human DNA repair enzyme HAP1: identification of residues important for AP endonuclease and RNase H activity

1995 • 119 citations

A mouse DNA repair enzyme (APEX nuclease) having exonuclease and apurinic/apyrimidinic endonuclease activities: purification and characterization

1991 • 83 citations

Single amino acid changes alter the repair specificity of Drosophila Rrp1. Isolation of mutants deficient in repair of oxidative DNA damage.

1994 • 21 citations