Structure and function of apurinic/apyrimidinic endonucleases

Instability and decay of the primary structure of DNA

1993 • 5,370 citations

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence

1991 • 1,501 citations

REPAIR OF OXIDATIVE DAMAGE TO DNA: Enzymology and Biology

1994 • 1,435 citations

Structural basis for the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism.

1991 • 1,059 citations

Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme.

1992 • 920 citations

Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity.

1992 • 702 citations

Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes.

1991 • 526 citations

Endonuclease IV (nfo) mutant of Escherichia coli

1986 • 397 citations

Structure and function of the multifunctional DNA-repair enzyme exonuclease III

1995 • 382 citations

The enzymology of apurinic/apyrimidinic endonucleases

1990 • 378 citations

The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains.

1994 • 351 citations

Structure of DNase I at 2.0 Å resolution suggests a mechanism for binding to and cutting DNA

1986 • 327 citations

Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects inE.coli xth(exonuclease III) mutants

1991 • 294 citations

Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding.

1993 • 270 citations

Ap endonucleases and dna glycosylases that recognize oxidative dna damage

1988 • 254 citations

Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia.

1994 • 241 citations

A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress

1994 • 221 citations

Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation.

1991 • 211 citations

Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV.

1990 • 199 citations

Identification of critical active-site residues in the multifunctional human DNA repair enzyme HAP1

1995 • 130 citations

Repair of intrinsic DNA lesions

1990 • 126 citations

Stable expression in rat glioma cells of sense and antisense nucleic acids to a human multifunctional DNA repair enzyme, APEX nuclease

1994 • 121 citations

Isolation of cDNA clones encoding an enzyme from bovine cells that repairs oxidative DNA damagein vitro: homology with bacterial repair enzymes

1991 • 120 citations

cDNA and deduced amino acid sequence of a mouse DNA repair enzyme (APEX nuclease) with significant homology to Escherichia coli exonuclease III.

1991 • 109 citations

Recognition of oxidized abasic sites by repair endonucleases

1994 • 99 citations

The Arabidopsis thaliana apurinic endonuclease Arp reduces human transcription factors Fos and Jun.

1994 • 88 citations

A mouse DNA repair enzyme (APEX nuclease) having exonuclease and apurinic/apyrimidinic endonuclease activities: purification and characterization

1991 • 83 citations

Nucleotide sequence of the xth gene of Escherichia coli K-12

1988 • 82 citations

Drosophila Rrp1 protein: an apurinic endonuclease with homologous recombination activities.

1991 • 62 citations

Structure of the human DNA repair geneHAP1and its localisation to chromosome 14q 11.2–12

1992 • 58 citations

Drosophila melanogaster Strand Transferase

1989 • 56 citations

The exoA gene of Streptococcus pneumoniae and its product, a DNA exonuclease with apurinic endonuclease activity

1989 • 52 citations

Biological Responses of Human Apurinic Endonuclease to Radiation‐Induced DNA Damage

1994 • 46 citations

Human apurinic endonuclease gene (APE): structure and genomic mapping (chromosome 1 4q11.2 - 12)

1992 • 31 citations

DNA Damage: Effects on DNA Structure and Protein Recognition

1994 • 26 citations

Single amino acid changes alter the repair specificity of Drosophila Rrp1. Isolation of mutants deficient in repair of oxidative DNA damage.

1994 • 21 citations

Drosophila RrplcomplementsE.coli xth nfomutants: protection against both oxidative and alkylation-induced DNA damage

1993 • 19 citations

Structure of DNase I

1991 • 18 citations

Cloning of the multifunctional<u>r</u>at<u>ap</u>urinic/apyrimidinic<u>e</u>ndo<u>n</u>uclease (rAPEN)/redox factor from an immature T cell line

1994 • 18 citations

Expression of Drosophila Rrp1 protein in Escherichia coli. Enzymatic and physical characterization of the intact protein and a carboxyl-terminally deleted exonuclease-deficient mutant.

1993 • 18 citations

Retransposition of the Drosophilia LINE I Element Can Induce Deletion in the Target DNA: A Simple Model Also Accounting for the Variability of the Normally Observed Target Site Duplications

1994 • 12 citations