Selection and Long-Term Persistence of Reactive CTL Clones During an EBV Chronic Response Are Determined by Avidity, CD8 Variable Contribution Compensating for Differences in TCR Affinities

MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness

1979 • 1,969 citations

Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains.

1994 • 1,400 citations

An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex

1996 • 1,282 citations

Detection of intracellular cytokines by flow cytometry

1993 • 992 citations

Structural Basis of Plasticity in T Cell Receptor Recognition of a Self Peptide-MHC Antigen

1998 • 685 citations

Human T-cell receptor variable gene segment families

1995 • 663 citations

Major expansion of CD8+ T cells with a predominant Vβ usage during the primary immune response to HIV

1994 • 611 citations

Coordinate Regulation of Complex T Cell Populations Responding to Bacterial Infection

1998 • 535 citations

Enhanced Generation of Specific Tumor-Reactive CTL In Vitro by Selected Melan-A/MART-1 Immunodominant Peptide Analogues

1998 • 487 citations

Crystal structure of the complex between human CD8αα and HLA-A2

1997 • 471 citations

Cell-cell adhesion mediated by CD8 and MHC class I molecules

1988 • 445 citations

Two Human T Cell Receptors Bind in a Similar Diagonal Mode to the HLA-A2/Tax Peptide Complex Using Different TCR Amino Acids

1998 • 438 citations

The Complete 685-Kilobase DNA Sequence of the Human β T Cell Receptor Locus

1996 • 434 citations

Immediate Early and Early Lytic Cycle Proteins Are Frequent Targets of the Epstein-Barr Virus–induced Cytotoxic T Cell Response

1997 • 362 citations

CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes

1996 • 326 citations

Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide.

1991 • 286 citations

CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes

1995 • 245 citations

Conserved T Cell Receptor Repertoire in Primary and Memory CD8 T Cell Responses to an Acute Viral Infection

1998 • 229 citations

Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL.

1996 • 222 citations

Evolution of a Complex T Cell Receptor Repertoire during Primary and Recall Bacterial Infection

1998 • 202 citations

T cell response to Epstein-Barr virus transactivators in chronic rheumatoid arthritis.

1996 • 174 citations

Epitope focusing in the primary cytotoxic T cell response to Epstein-Barr virus and its relationship to T cell memory.

1996 • 171 citations

The Human T-Cell Receptor TCRAC/TCRDC (Cα/Cdelta;) Region: Organization, Sequence, and Evolution of 97.6 kb of DNA

1994 • 169 citations

Alanine Scanning Mutagenesis of an αβ T Cell Receptor: Mapping the Energy of Antigen Recognition

1998 • 163 citations

MHC Class I/Peptide Stability: Implications for Immunodominance, In Vitro Proliferation, and Diversity of Responding CTL

1998 • 149 citations

Peripheral selection of antigen receptor junctional features in a major human γδ subset

1993 • 129 citations

Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR.

1995 • 121 citations

Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes.

1991 • 117 citations

Epitope-dependent Selection of Highly Restricted or Diverse T Cell Receptor Repertoires in Response to Persistent Infection by Epstein-Barr Virus

1997 • 106 citations

Correlation Between the Number of T Cell Receptors Required for T Cell Activation and TCR–Ligand Affinity

1996 • 103 citations

The MHC class l-restricted T cell response to Sendai virus infection in C57BL/6 mice: a single immunodominant epitope elicits an extremely diverse repertoire of T cells

1994 • 95 citations

Quantitative Contribution of CD4 and CD8 to T Cell Antigen Receptor Serial Triggering

1997 • 94 citations

The Clonal Composition of a Peptide-Specific Oligoclonal CTL Repertoire Selected in Response to Persistent EBV Infection Is Stable Over Time

1998 • 67 citations

Selection of T cells reactive against autologous B lymphoblastoid cells during chronic rheumatoid arthritis.

1996 • 55 citations

T-cell receptors from virus-specific cytotoxic T lymphocytes recognizing a single immunodominant nine-amino-acid viral epitope show marked diversity

1994 • 43 citations

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