Human exonuclease I interacts with the mismatch repair protein hMSH2.

CpG Islands in vertebrate genomes

1987 • 3,315 citations

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

1993 • 2,884 citations

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

1993 • 2,282 citations

Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer

1994 • 1,544 citations

Mutator phenotype may be required for multistage carcinogenesis.

1991 • 1,327 citations

Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

1995 • 824 citations

An STS-Based Map of the Human Genome

1995 • 782 citations

Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression.

1997 • 751 citations

DNA Replication Fidelity

2004 • 737 citations

Biochemistry and genetics of eukaryotic mismatch repair.

1996 • 598 citations

DNA Mismatch Correction in a Defined System

1989 • 551 citations

hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6

1996 • 541 citations

Fidelity of DNA Synthesis

1982 • 516 citations

Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes.

1996 • 465 citations

Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.

1990 • 408 citations

Identification and characterization of Saccharomyces cerevisiae EXO1 , a gene encoding an exonuclease that interacts with MSH2

1997 • 382 citations

The Human Mismatch Recognition Complex hMSH2-hMSH6 Functions as a Novel Molecular Switch

1997 • 357 citations

Identification of mismatch repair genes and their role in the development of cancer

1995 • 319 citations

Statistical methods for multipoint radiation hybrid mapping.

1991 • 288 citations

Frameshift somatic mutations in gastrointestinal cancer of the microsatellite mutator phenotype.

1997 • 254 citations

Strand-specific Mismatch Repair in Mammalian Cells

1997 • 253 citations

Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae.

1994 • 236 citations

Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction

1993 • 224 citations

Methyl-directed mismatch repair is bidirectional

1993 • 208 citations

The Saccharomyces cerevisiae Msh2 and Msh6 Proteins Form a Complex That Specifically Binds to Duplex Oligonucleotides Containing Mismatched DNA Base Pairs

1996 • 168 citations

Single-Strand DNA-Specific Exonucleases in Escherichia coli: Roles in Repair and Mutation Avoidance

1998 • 138 citations

A DNA exonuclease induced during meiosis of Schizosaccharomyces pombe.

1992 • 119 citations

Fidelity of mammalian DNA replication and replicative DNA polymerases

1991 • 119 citations

Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes Holliday junctions in DNA

1997 • 94 citations

A hPMS2 Mutant Cell Line Is Defective in Strand-specific Mismatch Repair

1995 • 89 citations