Shifts in Lung Lymphocyte Profiles Correlate with the Sequential Development of Acute Allergic and Chronic Tolerant Stages in a Murine Asthma Model

IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement.

1980 • 835 citations

Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.

1989 • 778 citations

The Role of Helper T Cell Products in Mouse B Cell Differentiation and Isotype Regulation

1988 • 764 citations

A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma.

1986 • 727 citations

Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo

1995 • 672 citations

Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia.

1994 • 498 citations

Immune responses to dietary antigens: oral tolerance

1998 • 462 citations

Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors.

1996 • 436 citations

Regulation of IgE Responses to Inhaled Antigen in Mice by Antigen-Specific γδ T Cells

1994 • 406 citations

Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function.

1989 • 356 citations

CD4⁺T-Lymphocytes and Interleukin-5 Mediate Antigen-induced Eosinophil Infiltration into the Mouse Trachea

1992 • 353 citations

The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T cell-mediated but MHC class II-restricted CD4+ T cell-dependent immune deviation resulting in selective suppression of immunoglobulin E production.

1993 • 317 citations

Central role of immunoglobulin (Ig) E in the induction of lung eosinophil infiltration and T helper 2 cell cytokine production: inhibition by a non-anaphylactogenic anti-IgE antibody.

1996 • 304 citations

Interleukin 13 is a B cell stimulating factor.

1994 • 298 citations

Requirement for γδ T Cells in Allergic Airway Inflammation

1998 • 268 citations

Cytokine and eosinophil responses in the lung, peripheral blood, and bone marrow compartments in a murine model of allergen-induced airways inflammation.

1997 • 225 citations

Characterization of a Murine Model of Allergic Pulmonary Inflammation

1994 • 214 citations

Lung inflammation and epithelial changes in a murine model of atopic asthma.

1996 • 208 citations

Interleukin-4-dependent pulmonary eosinophil infiltration in a murine model of asthma.

1994 • 172 citations

Gamma delta T cells down-regulate primary IgE responses in rats to inhaled soluble protein antigens.

1995 • 167 citations

MHC class II expression by the gut epithelium

1988 • 164 citations

Aerosol-induced Immunoglobulin (Ig)-E Unresponsiveness to Ovalbumin Does Not Require CD8+ or T Cell Receptor (TCR)-γ/δ+ T Cells or Interferon (IFN)-γ in a Murine Model of Allergen Sensitization

1998 • 155 citations

Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice

1997 • 133 citations

“Helper” (CD4⁺) T Cells and Eosinophils in Allergy and Asthma

1992 • 109 citations

Differential cellular analysis of bronchoalveolar lavage fluid obtained at various stages during the development of bleomycin-induced pulmonary fibrosis in the rat.

1982 • 100 citations

Suppression of IgE responses by antigen inhalation: studies on the role of genetic and environmental factors.

1987 • 86 citations

Importance of lnterleukin-4 and lnterleukin-12 in Allergen-Induced Airway Changes in Mice

1995 • 74 citations

Phenotypic and molecular characteristics of nasal mucosal gamma delta T cells in allergic and infectious rhinitis.

1996 • 74 citations

Increased Allergen-Specific, Steroid-Sensitive γδ T Cells in Bronchoalveolar Lavage Fluid from Patients with Asthma

1996 • 73 citations

Phenotypic characterization of T lymphocytes emigrating into lung tissue and the airway lumen after antigen inhalation in sensitized mice.

1995 • 67 citations

Regulation of IgE synthesis in humans

1989 • 64 citations

Reduction of Antigen-induced Airway Hyperreactivity and Eosinophilia in ICAM-1-deficient Mice

1998 • 58 citations

γδ T cells, allergen recognition and airway inflammation

1998 • 45 citations

Unique Features of Antigen Presentation in the Intestinea

1992 • 27 citations

Immunoregulation of the allergic reaction in the respiratory tract.

1996 • 24 citations

Reversal of A23187-induced airway constriction in the guinea pig.

1989 • 20 citations

Methacholine-induced pulmonary gas trapping in guinea pigs, hamsters, mice, and rats

1995 • 18 citations

Characterization of the Antigen-Presenting Cell and T Cell Requirements for Induction of Pulmonary Eosinophilia in a Murine Model of Asthma

1996 • 13 citations

Effect of bronchoconstrictive aerosols on pulmonary gas trapping in the A/J mouse

1995 • 8 citations

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