Packaging capacity and stability of human adenovirus type 5 vectors

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

High efficiency transformation of E.coli by high voltage electroporation

1988 • 2,789 citations

In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

1992 • 953 citations

Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

1979 • 785 citations

Manipulation of Adenovirus Vectors

2003 • 780 citations

An Adenovirus Vector for Gene Transfer into Neurons and Glia in the Brain

1993 • 746 citations

Adenovirus-Mediated Transfer of a Recombinant α1-Antitrypsin Gene to the Lung Epithelium in Vivo

1991 • 743 citations

Widespread long-term gene transfer to mouse skeletal muscles and heart.

1992 • 586 citations

Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice

1993 • 455 citations

Adenovirus–mediated in vivo gene transfer and expression in normal rat liver

1992 • 451 citations

Adenovirus VAI RNA is required for efficient translation of viral mRNAs at late times after infection

1982 • 395 citations

Evaluation of the Transfer and Expression in Mice of an Enzyme-Encoding Gene Using a Human Adenovirus Vector

1990 • 325 citations

Adenovirus as an expression vector in muscle cells in vivo.

1992 • 301 citations

Adenovirus-Based Expression Vectors and Recombinant Vaccines

1992 • 252 citations

Isolation of deletion and substitution mutants of adenovirus type 5

1978 • 230 citations

Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer.

1993 • 199 citations

Expression of Heterologous Sequences in Adenoviral Vectors

1992 • 171 citations

Sequence Heterogeneity in Closed Simian Virus 40 Deoxyribonucleic Acid

1972 • 148 citations

A Recombinant Human Adenovirus Vaccine against Rabies

1990 • 145 citations

Immunogenicity and efficacy testing in chimpanzees of an oral hepatitis B vaccine based on live recombinant adenovirus.

1989 • 144 citations

Generation of adenovirus by transfection of plasmids

1983 • 144 citations

Monitoring foreign gene expression by a human adenovirus-based vector using the firefly luciferase gene as a reporter

1993 • 141 citations

Protein IX, a minor component of the human adenovirus capsid, is essential for the packaging of full length genomes.

1987 • 134 citations

Recombinant adenovirus induces antibody response to hepatitis B virus surface antigen in hamsters.

1987 • 130 citations

DNA sequence of the early E3 transcription unit of adenovirus 5

1985 • 116 citations

Development of a helper-independent human adenovirus vector and its use in the transfer of the herpes simplex virus thymidine kinase gene

1986 • 113 citations

High-level expression of the tick-borne encephalitis virus NS1 protein by using an adenovirus-based vector: protection elicited in a murine model

1992 • 98 citations

Covalently closed circles of human adenovirus DNA are infectious.

1984 • 98 citations

Protection of mice against lethal challenge with herpes simplex virus by vaccination with an adenovirus vector expressing hsv glycoprotein B

1989 • 90 citations

Construction of a defective adenovirus vector expressing the pseudorabies virus glycoprotein gp50 and its use as a live vaccine

1990 • 89 citations

Synthesis and processing of human immunodeficiency virus type 1 envelope proteins encoded by a recombinant human adenovirus

1989 • 79 citations

Oral rabies vaccination of skunks and foxes with a recombinant human adenovirus vaccine

1992 • 79 citations

Human adenovirus cloning vectors based on infectious bacterial plasmids

1986 • 75 citations

Abundant expression of herpes simplex virus glycoprotein gB using an adenovirus vector

1988 • 74 citations

Herpes simplex virus IgG Fc receptors induced using recombinant adenovirus vectors expressing glycoproteins E and I

1990 • 59 citations

Immune response to HIV-1 gag antigens induced by recombinant adenovirus vectors in mice and rhesus macaque monkeys.

1991 • 59 citations

Genetic Analysis of Adenoviruses

1984 • 58 citations

Characterization of mutants within the gene for the adenovirus E3 14.7-kilodalton protein which prevents cytolysis by tumor necrosis factor

1993 • 55 citations

Abundant expression of polyomavirus middle T antigen and dihydrofolate reductase in an adenovirus recombinant

1987 • 53 citations

Expression of human α₁‐antitrypsin using a recombinant adenovirus vector

1990 • 50 citations

Cloning of the herpes simplex virus ICP4 Gene in an adenovirus vector: Effects on adenovirus gene expression and replication

1989 • 48 citations

Expression of the Glycoprotein of Vesicular Stomatitis Virus by Infectious Adenovirus Vectors

1989 • 44 citations

Coexpression of the simian immunodeficiency virus Env and Rev proteins by a recombinant human adenovirus host range mutant

1992 • 37 citations

Evaluation of adenovirus type 4 and type 7 recombinant hepatitis B vaccines in dogs

1991 • 35 citations

Formation of deletions after initiation of simian virus 40 replication: influence of packaging limit of the capsid

1986 • 31 citations

High Level Expression in 293 Cells of the Herpes Simplex Virus Type 2 Ribonucleotide Reductase Subunit 2 Using an Adenovirus Vector

1990 • 28 citations

Adenovirus Vectors as Potential Vaccines Against Herpes Simplex Virus

1991 • 20 citations

Overexpression of the Human Vitamin D₃Receptor in Mammalian Cells using Recombinant Adenovirus Vectors

1991 • 17 citations

Co-expression of hepatitis B virus antigens by a non-defective adenovirus vaccine vector

1991 • 13 citations

Helper Independent Recombinant Adenovirus Vectors: Expression of HIVenvor HBV Surface Antigen

1990 • 7 citations

Thiopurine Methyltransferase Activity and Efficacy of Azathioprine Immunosuppression in Transplant Recipients

1991 • 7 citations

Preferential Expression Of The Large Hepatitis B Virus Surface Antigen Gene by an Adenovirus-hepatitis B Virus Recombinant

1991 • 6 citations

Expression of the APRT Gene in an Adenovirus Vector System as a Model for Studying Gene Therapy

1991 • 2 citations