Thiopurine Methyltransferase Activity and Efficacy of Azathioprine Immunosuppression in Transplant Recipients

Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity.

1980 • 1,185 citations

Pharmacogenetics of acute azathioprine toxicity: Relationship to thiopurine methyltransferase genetic polymorphism

1989 • 605 citations

Prolonged Survival of Human-Kidney Homografts by Immunosuppressive Drug Therapy

1963 • 544 citations

Human erythrocyte thiopurine methyltransferase: Radiochemical microassay and biochemical properties

1978 • 351 citations

A biochemical mechanism for the delayed cytotoxic reaction of 6-mercaptopurine.

1974 • 284 citations

Azathioprine Metabolism: Pharmacokinetics of 6‐Mercaptopurine, 6‐Thiouric Acid and 6‐Thioguanine Nucleotides in Renal Transplant Patients

1990 • 121 citations

Prolonged Survival of Human-Kidney Homografts by Immunosuppressive Drug Therapy

1984 • 44 citations

Disturbance of 6-mercaptopurine metabolism by cotrimoxazole in childhood lymphoblastic leukaemia

1984 • 22 citations