Real-Time Analysis of Mural Thrombus Formation in Various Platelet Aggregation Disorders: Distinct Shear-Dependent Roles of Platelet Receptors and Adhesive Proteins Under Flow

The Pathogenesis of Coronary Artery Disease and the Acute Coronary Syndromes

1992 • 2,655 citations

The pathogenesis of coronary artery disease and the acute coronary syndromes (First of two parts)

1992 • 1,958 citations

Initiation of Platelet Adhesion by Arrest onto Fibrinogen or Translocation on von Willebrand Factor

1996 • 1,178 citations

Platelets and shear stress

1996 • 871 citations

Specific Synergy of Multiple Substrate–Receptor Interactions in Platelet Thrombus Formation under Flow

1998 • 809 citations

Variant von Willebrand's Disease

1980 • 516 citations

Platelet Physiology and Abnormalities of Platelet Function

1975 • 444 citations

Decreased adhesion of platelets to subendothelium in von Willebrand's disease.

1974 • 391 citations

Design and construction of a linear shear stress flow chamber

1993 • 308 citations

Distinct mechanisms of platelet aggregation as a consequence of different shearing flow conditions.

1998 • 286 citations

Real-time analysis of shear-dependent thrombus formation and its blockade by inhibitors of von Willebrand factor binding to platelets

1993 • 271 citations

Characterization of the Unique Mechanism Mediating the Shear-dependent Binding of Soluble von Willebrand Factor to Platelets

1995 • 266 citations

Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium

1974 • 265 citations

Fibrinogen-independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb-IIIa complex at high shear rate.

1989 • 260 citations

Platelet adhesion to collagen types I through VIII under conditions of stasis and flow is mediated by GPIa/IIa (alpha 2 beta 1-integrin)

1994 • 256 citations

von Willebrand factor.

1997 • 252 citations

Platelet Physiology and Abnormalities of Platelet Function

1975 • 226 citations

Platelet adhesion and thrombus formation on subendothelium in platelets deficient in glycoproteins IIb-IIIa, Ib, and storage granules

1986 • 215 citations

Transmembrane Calcium Influx Associated with von Willebrand Factor Binding to GP Ib in the Initiation of Shear-Induced Platelet Aggregation

1993 • 171 citations

Platelet adhesion and thrombus formation on subendothelium in platelets deficient in glycoproteins IIb-IIIa, Ib, and storage granules

1986 • 170 citations

The hemostatic plug.

1977 • 169 citations

Role of shear rate and platelets in promoting fibrin formation on rabbit subendothelium. Studies utilizing patients with quantitative and qualitative platelet defects.

1986 • 169 citations

Analysis of platelet adhesion to a collagen-coated surface under flow conditions: the involvement of glycoprotein VI in the platelet adhesion

1996 • 153 citations

Identification of discontinuous von Willebrand factor sequences involved in complex formation with botrocetin. A model for the regulation of von Willebrand factor binding to platelet glycoprotein Ib.

1991 • 135 citations

Platelet adhesion and aggregation on human type VI collagen surfaces under physiological flow conditions

1995 • 89 citations

Analysis of the Involvement of the von Willebrand Factor–Glycoprotein Ib Interaction in Platelet Adhesion to a Collagen-Coated Surface Under Flow Conditions

1997 • 84 citations

Functional modulation of the isolated glycoprotein Ib binding domain of von Willebrand factor expressed in Escherichia coli

1991 • 82 citations

Platelets deficient in glycoprotein IIIb aggregate normally to collagens type I and III but not to collagen type V

1993 • 65 citations

Evolution by polyploidy in Amphibia: new insights

1998 • 60 citations

Analysis of structure-function relationships in the platelet membrane glycoprotein Ib-binding domain of von Willebrand's factor by expression of deletion mutants

1993 • 58 citations

Shear-dependent functions of the interaction between soluble von Willebrand factor and platelet glycoprotein Ib in mural thrombus formation on a collagen surface.

1999 • 32 citations

Role and initiation mechanism of the interaction of glycoprotein Ib with surface-immobilized von Willebrand factor in a solid-phase platelet cohesion process

1996 • 21 citations

Structural elements influencing von Willebrand factor (vWF) binding affinity for platelet glycoprotein Ib within a dispase-digested vWF fragment

1994 • 16 citations

Comparative Studies on the Antiplatelet Effects of a Humanized Anti-Platelet Glycoprotein IIb/IIIa Antibody (YM337) and ReoPro under Flow Conditions

1998 • 16 citations