Fibrinogen-independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb-IIIa complex at high shear rate.

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

1984 • 3,580 citations

The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

1973 • 3,279 citations

The hydrolysis of rabbit γ-globulin and antibodies with crystalline papain

1959 • 2,294 citations

Binding of soluble form of fibroblast surface protein, fibronectin, to collagen

1977 • 1,972 citations

The platelet membrane glycoprotein IIb-IIIa complex

1988 • 1,031 citations

Platelet Membrane Glycoprotein IIb/IIIa: Member of a Family of Arg-Gly-Asp—Specific Adhesion Receptors

1986 • 945 citations

Human blood platelet adhesion to artery subendothelium is mediated by factor VIII–Von Willebrand factor bound to the subendothelium

1979 • 652 citations

Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress-induced platelet aggregation.

1986 • 609 citations

The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets.

1985 • 594 citations

The role of blood flow in platelet adhesion, fibrin deposition, and formation of mural thrombi

1973 • 587 citations

Rheological aspects of thrombosis and haemostasis: basic principles and applications. ICTH-Report--Subcommittee on Rheology of the International Committee on Thrombosis and Haemostasis.

1986 • 486 citations

Platelet receptor recognition site on human fibrinogen. Synthesis and structure-function relationship of peptides corresponding to the carboxy-terminal segment of the .gamma. chain

1984 • 479 citations

Studies with a murine monoclonal antibody that abolishes ristocetin- induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor

1983 • 469 citations

Platelets have more than one binding site for von Willebrand factor.

1983 • 459 citations

The tetrapeptide analogue of the cell attachment site of fibronectin inhibits platelet aggregation and fibrinogen binding to activated platelets.

1985 • 437 citations

Complete amino acid sequence of human vitronectin deduced from cDNA. Similarity of cell attachment sites in vitronectin and fibronectin.

1985 • 418 citations

Decreased adhesion of platelets to subendothelium in von Willebrand's disease.

1974 • 391 citations

Molecular Defects in Interactions of Platelets with the Vessel Wall

1984 • 381 citations

Effect of shear rate on platelet interaction with subendothelium in citrated and native blood. I. Shear rate--dependent decrease of adhesion in von Willebrand's disease and the Bernard-Soulier syndrome.

1978 • 368 citations

Rheological Aspects of Thrombosis and Haemostasis: Basic Principles and Applications

1986 • 366 citations

Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen.

1982 • 324 citations

Specific and saturable binding of plasma fibronectin to thrombin-stimulated human platelets.

1981 • 300 citations

Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by a synthetic tetrapeptide derived from the cell-binding domain of fibronectin

1985 • 299 citations

Shear-induced platelet aggregation requires von Willebrand factor and platelet membrane glycoproteins Ib and IIb-IIIa

1987 • 291 citations

Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium

1974 • 265 citations

Glanzmann thrombasthenia: deficient binding of von Willebrand factor to thrombin-stimulated platelets.

1982 • 261 citations

Increased surface expression of the membrane glycoprotein IIb/IIIa complex induced by platelet activation. Relationship to the binding of fibrinogen and platelet aggregation

1987 • 257 citations

Evidence that three adhesive proteins interact with a common recognition site on activated platelets.

1984 • 254 citations

Molecular cloning of S-protein, a link between complement, coagulation and cell-substrate adhesion.

1985 • 241 citations

Heterogeneity in storage pool deficiency: studies on granule-bound substances in 18 patients including variants deficient in alpha- granules, platelet factor 4, beta-thromboglobulin, and platelet-derived growth factor

1979 • 239 citations

The role of platelet membrane glycoproteins Ib and IIb-IIIa in platelet adherence to human artery subendothelium

1986 • 237 citations

Role of factor VIII-von Willebrand factor and fibronectin in the interaction of platelets in flowing blood with monomeric and fibrillar human collagen types I and III.

1985 • 225 citations

Evidence that arginyl-glycyl-aspartate peptides and fibrinogen gamma chain peptides share a common binding site on platelets.

1987 • 222 citations

Platelet adhesion and thrombus formation on subendothelium in platelets deficient in glycoproteins IIb-IIIa, Ib, and storage granules

1986 • 215 citations

[12] Isolation of human platelets and platelet surface membranes

1974 • 213 citations

Characterization of human S protein, an inhibitor of the membrane attack complex of complement. Demonstration of a free reactive thiol group

1985 • 212 citations

Deficiency of platelet membrane glycoprotein Ia associated with a decreased platelet adhesion to subendothelium: a defect in platelet spreading

1986 • 211 citations

Identification of the fibrinogen receptor on human platelets by photoaffinity labeling.

1982 • 197 citations

Thrombin-induced exposure and prostacyclin inhibition of the receptor for factor VIII/von Willebrand factor on human platelets.

1982 • 190 citations

Demonstration and characterization of specific binding sites for factor VIII/von Willebrand factor on human platelets.

1979 • 182 citations

Studies on gel-filtered human platelets: isolation and characterization in a medium containing no added Ca2+, Mg2+, or K+.

1975 • 181 citations

Bernard-Soulier syndrome: a new platelet glycoprotein abnormality. Its relationship with platelet adhesion to subendothelium and with the factor VIII von Willebrand protein.

1976 • 174 citations

von Willebrand factor interaction with the glycoprotein IIb/IIa complex. Its role in platelet function as demonstrated in patients with congenital afibrinogenemia.

1986 • 174 citations

Metabolism and Function of Human Platelets Washed by Albumin Density Gradient Separation

1977 • 169 citations

Correction by factor VIII of the impaired platelet adhesion to subendothelium in von Willebrand disease

1978 • 166 citations

Platelet interaction with subendothelium in flowing rabbit blood: Effect of blood shear rate

1979 • 161 citations

Extracellular matrices and cell adhesion.

1985 • 157 citations

gamma and alpha chains of human fibrinogen possess sites reactive with human platelet receptors.

1982 • 156 citations

Platelet interaction with rabbit subendothelium in von Willebrand's disease: altered thrombus formation distinct from defective platelet adhesion.

1984 • 153 citations

The different glycoprotein abnormalities in thrombasthenic and Bernard-Soulier platelets.

1979 • 133 citations

Exposure of binding sites for vitronectin on platelets following stimulation.

1988 • 122 citations

Fibrinogen and Platelets in the Primary Arrest of Bleeding

1971 • 121 citations

Fibrinogen competes with von Willebrand factor for binding to the glycoprotein IIb/IIIa complex when platelets are stimulated with thrombin

1984 • 119 citations

Analysis of pulsatile, viscous blood flow through diseased coronary arteries of man

1977 • 118 citations

Heterogeneous abnormalities in the multimeric structure, antigenic properties, and plasma-platelet content of factor VIII/von Willebrand factor in subtypes of classic (type I) and variant (type IIA) von Willebrand's disease.

1983 • 104 citations

Adenosine diphosphate induces binding of von Willebrand factor to human platelets

1982 • 102 citations

Independent modulation of von Willebrand factor and fibrinogen binding to the platelet membrane glycoprotein IIb/IIIa complex as demonstrated by monoclonal antibody.

1985 • 100 citations

Evidence for tissue factor-dependent activation of the classic extrinsic coagulation mechanism in blood obtained from bleeding time wounds

1988 • 99 citations

Binding of radioiodinated human von Willebrand factor to Bernard-Soulier, thrombasthenic and von Willebrand's disease platelets

1980 • 96 citations

Interaction of von Willebrand factor with human platelets in the plasma milieu.

1984 • 95 citations

Fibronectin in artery subendothelium is important for platelet adhesion

1985 • 94 citations

Mapping of distinct von Willebrand factor domains interacting with platelet GPIb and GPIIb/IIIa and with collagen using monoclonal antibodies

1986 • 93 citations

ROLE OF VON WILLEBRAND FACTOR IN PLATELET ADHESION TO THE SUBENDOTHELIUM

1983 • 86 citations

ADP-dependent common receptor mechanism for binding of von Willebrand factor and fibrinogen to human platelets.

1984 • 79 citations

Inhibition of von Willebrand factor–platelet interaction by fibrinogen

1984 • 72 citations

Fibrinogen Philadelphia. A hereditary hypodysfibrinogenemia characterized by fibrinogen hypercatabolism.

1974 • 71 citations

Identification of platelet glycoprotein IIb/IIIa as the major binding site for released platelet-von Willebrand factor [published erratum appears in Blood 1987 Jun;69(6):1789]

1986 • 67 citations

Fibronectin is required for platelet adhesion and for thrombus formation on subendothelium and collagen surfaces

1987 • 66 citations

Shear stress activation of platelet glycoprotein IIb/IIIa plus von Willebrand factor causes aggregation: filter blockage and the long bleeding time in von Willebrand's disease

1987 • 66 citations

Decreased platelet adhesion on vessel segments in von Willebrand's disease: a defect in initial platelet attachment.

1983 • 63 citations

Factor-VIII/von Willebrand factor

2015 • 61 citations

ROLE OF VON WILLEBRAND FACTOR IN PLATELET ADHESION TO THE SUBENDOTHELIUM

1983 • 59 citations

Quantitation of fragment X formation during thrombolytic therapy with streptokinase and tissue plasminogen activator.

1987 • 54 citations

Platelet von Willebrand factor: evidence for its involvement in platelet adhesion to collagen

1987 • 51 citations

Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency

1984 • 51 citations

Inhibition of platelet aggregation by fibronectin

1983 • 46 citations

Platelet retention in glass bead columns: adhesion to glass and subsequent platelet-platelet interactions

1976 • 45 citations

Fibrinogen-independent aggregation and deaggregation of human platelets: studies in two afibrinogenemic patients

1987 • 44 citations

Von Willebrand factor has more than one binding site for platelets

1984 • 42 citations

Human plasma fibronectin promotes the adhesion and spreading of platelets on surfaces coated with fibrillar collagen

1981 • 41 citations

The synthetic RGDS peptide inhibits the binding of fibrinogen lacking intact alpha chain carboxyterminal sequences to human blood platelets

1987 • 40 citations

Platelet aggregation occurs in congenital afibrinogenaemia despite the absence of fibrinogen or its fragments in plasma and platelets, as demonstrated by immunoenzymology

1985 • 33 citations

Monoclonal antibodies to the glycoprotein IIb-IIIa epitopes involved in adhesive protein binding: effects on platelet spreading and ultrastructure on human arterial subendothelium.

1987 • 31 citations

A Preliminary Comparison of the Thrombogenic Activity of Vitronectin and Other RGD‐containing Proteins When Bound to Surfacesa

1987 • 31 citations

The inhibitory effect of plasma fibronectin on collagen-induced platelet aggregation

1986 • 28 citations

Binding of fibrinogen to ADP-treated platelets. Comparison of plasma fibrinogen fractions and early plasmic fibrinogen derivatives.

1983 • 27 citations

The effect of human fibronectin on platelet - collagen adhesion

1980 • 23 citations

Characterization of calcium-dependent binding of endogenous factor VIII/von Willebrand factor to surface activated platelets

1984 • 22 citations

[6] Radioimmunoassay of platelet factor 4

1982 • 20 citations

Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by a synthetic tetrapeptide derived from the cell-binding domain of fibronectin

1985 • 19 citations

PLATELET/SURFACE INTERACTIONS

2000 • 17 citations

Deficiency of platelet membrane glycoprotein Ia associated with a decreased platelet adhesion to subendothelium: a defect in platelet spreading

1986 • 14 citations

Factor VIII—von Willebrand Factor

2021 • 13 citations

Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium. Further implications on the role of the von Willebrand factor in hemostasis

1974 • 13 citations

von Willebrand factor can substitute for plasma fibrinogen in ADP-induced platelet aggregation.

1986 • 13 citations

Platelet Adhesion: Past and Present

1985 • 11 citations

Fibrinogen competes with von Willebrand factor for binding to the glycoprotein IIb/IIIa complex when platelets are stimulated with thrombin

1984 • 10 citations

Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency

1984 • 9 citations

Mapping of distinct von Willebrand factor domains interacting with platelet GPIb and GPIIb/IIIa and with collagen using monoclonal antibodies

1986 • 8 citations

Mechanism triggering platelet hemostatic plug formation in vivo.

1984 • 8 citations

Effect of monoclonal antibodies against von Willebrand factor and platelet glycoproteins IIb/IIIa on the platelet retention test

1987 • 8 citations

Shear stress activation of platelet glycoprotein IIb/IIIa plus von Willebrand factor causes aggregation: filter blockage and the long bleeding time in von Willebrand's disease

1987 • 4 citations

Role of GPIIb/IIIa as well as GPIb in von Willebrand factor-mediated platelet adhesion to collagen

1986 • 4 citations

Platelet von Willebrand factor: evidence for its involvement in platelet adhesion to collagen

1987 • 4 citations

Fibrinogen-independent aggregation and deaggregation of human platelets: studies in two afibrinogenemic patients

1987 • 3 citations

Effect of monoclonal antibodies against von Willebrand factor and platelet glycoproteins IIb/IIIa on the platelet retention test

1987 • 2 citations

Platelets, Surfaces and Plasma Proteins in Platelet Adhesion

2015 • 2 citations

Role of cp iib iiia as well as gpi b in von willebrand factor mediated platelet adhesion to collagen

1986 • 1 citations

THE ARG-GLY-ASP(SER) SEQUENCE OF FIBRONECTIN, AND THE GLYCOPROTEIN IIB-IIIA COMPLEX ARE NOT INVOLVED IN FIBRONECTIN DEPENDENT PLATELET ADHESION IN FLOW

1987 • 1 citations