Platelet Physiology and Abnormalities of Platelet Function

Energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers

1968 • 2,371 citations

Synthesis of Antihemophilic Factor Antigen by Cultured Human Endothelial Cells

1973 • 1,303 citations

The synthesis of complex carbohydrates by multiglycosyltransferase systems and their potential function in intercellular adhesion

1970 • 1,208 citations

Actin And Myosin And Cell Movemen

1974 • 1,018 citations

Isolation and Structure of Two Prostaglandin Endoperoxides That Cause Platelet Aggregation

1974 • 1,004 citations

Adenosine Diphosphate in Red Cells as a Factor in the Adhesiveness of Human Blood Platelets

1961 • 781 citations

Immunologic differentiation of classic hemophilia (factor VIII deficiency) and von Willebrand's disease

1971 • 660 citations

Factors influencing platelet function: adhesion, release, and aggregation.

1970 • 635 citations

Microtubules

1973 • 603 citations

MEASUREMENT OF PLATELET ADHESIVENESS. A SIMPLE IN VITRO TECHNIQUE DEMONSTRATING AN ABNORMALITY IN VON WILLEBRAND'S DISEASE.

1963 • 479 citations

An Abnormal Platelet Glycoprotein Pattern in Three Cases of Glanzmann's Thrombasthenia

1974 • 445 citations

Quantitative Assay of a Plasma Factor Deficient in von Willebrand's Disease that is Necessary for Platelet Aggregation. RELATIONSHIP TO FACTOR VIII PROCOAGULANT ACTIVITY AND ANTIGEN CONTENT

1973 • 421 citations

Specific roles for platelet surface glycoproteins in platelet function

1975 • 411 citations

Decreased adhesion of platelets to subendothelium in von Willebrand's disease.

1974 • 391 citations

Actomyosin-Like Protein in Brain

1973 • 364 citations

Lipid composition of subcellular particles of human blood platelets

1969 • 337 citations

Physiological role of an endoperoxide in human platelets: hemostatic defect due to platelet cyclo-oxygenase deficiency.

1975 • 312 citations

Isolation and Properties of a Thrombin-sensitive Protein of Human Platelets

1972 • 306 citations

Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium

1974 • 265 citations

Interaction of membrane systems in blood platelets.

1972 • 264 citations

Defective Ristocetin-Induced Platelet Aggregation in von Willebrand's Disease and its Correction by Factor VIII

1973 • 222 citations

Platelet secretion induced by divalent cation ionophores

1974 • 215 citations

Cyclic AMP and Platelet Function

1972 • 213 citations

Platelet Function in Renal Failure

1969 • 213 citations

Formation of an Intermediate in Prostaglandin Biosynthesis and Its Association with the Platelet Release Reaction

1974 • 203 citations

Further Evidence for a Deficient Storage Pool of Adenine Nucleotides in Platelets From Some Patients With Thrombocytopathia—"Storage Pool Disease"

1972 • 196 citations

Effects of the lonophore A23187 on blood platelets I. Influence on aggregation and secretion.

1974 • 186 citations

Hereditary Defect in the Platelet Release Reaction Caused by a Deficiency in the Storage Pool of Platelet Adenine Nucleotides

1970 • 181 citations

Wiskott—Aldrich Syndrome: Qualitative Platelet Defects and Short Platelet Survival

1969 • 180 citations

An endoperoxide aggregator (LASS), formed in platelets in response to thrombotic stimuli-purification, identification and unique biological significance

1974 • 178 citations

Immunological Characterization of Purified Anti-Haemophilic Factor A (Factor VIII) which corrects Abnormal Platelet Retention in Von Willebrand's Disease

1972 • 167 citations

Adenine nucleotide metabolism of blood platelets VI. Subcellular localization of nucleotide pools with different functions in the platelet release reaction

1969 • 155 citations

Platelet Function in a Patient with Thrombasthenia

1966 • 153 citations

Platelet aggregation, adhesion and adenosine diphosphate release in thrombopathia (platelet factor 3 deficiency)

1967 • 153 citations

BLEEDING TENDENCY ASSOCIATED WITH "NEW" ABNORMALITY OF PLATELET BEHAVIOUR

1967 • 152 citations

Von Willebrand Factor: Dissociation from Antihemophilic Factor Procoagulant Activity

1973 • 150 citations

Congenital Thrombocytopenia with Giant Platelets: a Defect in the Platelet Membrane

1969 • 145 citations

Evidence for a Structural Requirement for the Aggregation of Platelets by Collagen

1974 • 140 citations

Iodination of the Human Platelet Membrane

1973 • 140 citations

Platelet Function

1969 • 138 citations

Phagocytosis

1974 • 138 citations

ANTI-METASTATIC EFFECT OF ASPIRIN

1972 • 133 citations

Inherited Variants of Factor-VIII-Related Protein in von Willebrand's Disease

1974 • 133 citations

Release reaction and energy metabolism in blood platelets with special reference to the burst in oxygen uptake

1968 • 127 citations

A Familial Defect in Platelet Function Associated with Impaired Release of Adenosine Diphosphate

1969 • 127 citations

Hereditary Giant Platelet Syndrome: A Disorder of a New Aspect of Platelet Function

1973 • 124 citations

Platelet Coagulant Activities and Hemostasis: A Hypothesis

1974 • 120 citations

Hereditary Defect in Platelet Function in Rats

1972 • 118 citations

Effects of antimycin and 2-deoxyglucose on adenine nucleotides in human platelets. Role of metabolic adenosine triphosphate in primary aggregation, secondary aggregation and shape change of platelets

1974 • 118 citations

MOLECULAR STRUCTURAL STUDIES OF HUMAN FACTOR VIII*

1975 • 115 citations

A Variant of Factor VIII Related Antigen

1974 • 114 citations

Impaired Interaction (Adhesion-Aggregation) of Platelets with the Subendothelium in Storage-Pool Disease and after Aspirin Ingestion

1975 • 113 citations

Platelet adhesiveness and aggregation. II. Surface sialic acid, glycoprotein: N-acetylneuraminic acid transferase, and neuraminidase of human blood platelets.

1972 • 110 citations

Platelet Function and Coagulation Profile in Lupus Erythematosus

1974 • 110 citations

Platelet Contractile Regulation in an Isometric System

1973 • 109 citations

Platelet adhesiveness and aggregation: The collagen:Glycosyl, polypeptide:N-acetylgalactosaminyl and glycoprotein:Galactosyl transferases of human platelets

1971 • 107 citations

Collagen induced platelet aggregation: Requirement for tropocollagen multimers

1973 • 106 citations

Qualitative Platelet Abnormalities in Idiopathic Thrombocytopenic Purpura

1972 • 106 citations

The incorporation of acetate and palmitate into lipids by human platelets

1968 • 106 citations

Willebrand Factor and Ristocetin II. RELATIONSHIP BETWEEN WILLEBRAND FACTOR, WILLEBRAND ANTIGEN AND FACTOR‐VIII ACTIVITY

1974 • 106 citations

Immunologic Studies in von Willebrand's Disease

1972 • 105 citations

The Role of Collagen Quaternary Structure in the Platelet:Collagen Interaction

1974 • 103 citations

Microfibrils of blood platelets: their relationship to microtubules and the contractile protein

1969 • 102 citations

Possible Mechanism of Aggregation of Blood Platelets by Adenosine Diphosphate

1966 • 102 citations

Studies of platelets in a variant of the Hermansky-Pudlak syndrome.

1971 • 102 citations

Binding of Adenosine Diphosphate by Isolated Membranes from Human Platelets

1974 • 102 citations

Studies of Platelet 5-Hydroxytryptamine (Serotonin) in Storage Pool Disease and Albinism

1974 • 99 citations

A unified theory of the control of actin and myosin in nonmuscle movements

1974 • 97 citations

Expansion of the growth fraction in multiple myeloma with alkylating agents

1975 • 96 citations

Platelet Thrombosthenin: Subcellular Localization and Function*

1967 • 95 citations

The Platelet Defect Associated with Albinism

1972 • 93 citations

Platelet Adhesion in Vivo in Patients with Bleeding Disorders

1961 • 93 citations

Studies on the Proteins of Human Platelet Membranes

1972 • 91 citations

Uptake of Calcium by Platelet Relaxing Factor

1969 • 91 citations

Thrombocytopathia Due to Abnormalities in Platelet Release Reaction—Studies on Six Unrelated Patients

1972 • 90 citations

Hydrogen Peroxide and Platelet Function

1974 • 89 citations

Two Genetic Variants of von Willebrand's Disease

1973 • 86 citations

New aspects on the storage of 5-hydroxytryptamine in blood platelets

1971 • 85 citations

Book ReviewPlatelet Aggregation: Table ronde Roussel 4–5 mars, 1971.

1972 • 83 citations

Content and thrombin-induced release of acid hydrolases in gel-filtered platelets from patients with storage pool disease

1975 • 83 citations

Abnormalities of 5‐hydroxytryptamine uptake and binding by blood platelets from children with Down's syndrome

1971 • 83 citations

Acquired “storage pool disease” of platelets associated with circulating antiplatelet antibodies

1974 • 81 citations

Subcellular Particles of Human Platelets

1969 • 80 citations

PLASMA PROTEIN REQUIREMENTS FOR HUMAN PLATELET AGGREGATION

1972 • 76 citations

Detection of Heterozygotes for Recessive von Willebrand's Disease by the Assay of Antihemophilic-Factor-like Antigen

1973 • 75 citations

The localization of calcium and phosphorus in human platelets

1974 • 75 citations

Platelet Adenine Nucleotide "Storage Pool Deficiency" In Thrombocytopenic Absent Radii Syndrome

1972 • 74 citations

Critical Role of the Carbohydrate Side Chains of Collagen in Platelet Aggregation

1972 • 73 citations

Hereditary Giant Platelet Syndrome

1975 • 72 citations

Albinism and Abnormal Platelet Function

1971 • 72 citations

NATURE OF THE PLATELET DEFECT IN THE WISKOTT‐ALDRICH SYNDROME*

1972 • 71 citations

Studies of platelet function and proteins in 3 patients with Glanzmann's thrombasthenia.

1968 • 71 citations

Aggregation of Human Platelets by Bovine or Human Factor VIII: Role of Carbohydrate Side Chains

1973 • 68 citations

Biochemical energetics of simulated platelet plug formation

1968 • 67 citations

Impairment in Platelet Aggregation in Congenital Heart Disease

1972 • 67 citations

Changes in the Adenylate Energy Charge in Human Blood Platelets induced by Adenosine Diphosphate

1973 • 65 citations

Emerging Concepts of Platelet Function

1974 • 63 citations

The presence and reactions of high and lower-molecular-weight procoagulant factor VIII in the plasma of patients with von Willebrand's disease after treatment: Significance for a structural hypothesis for factor VIII

1973 • 63 citations

Abnormalities of factor VIII and platelet aggregation--use of ristocetin in diagnosing the von Willebrand syndrome

1975 • 63 citations

Platelet Clumping in vivo

1963 • 61 citations

The Actin and Myosin Filaments of Human and Bovine Blood Platelets

1972 • 61 citations

Availability of Platelet Factor 3 and Activation of Factor XII in Thrombasthenia

1965 • 60 citations

The Effects of Thrombin on Adenyl Cyclase Activity and a Membrane Protein from Human Platelets

1972 • 59 citations

Effects of normal and aspirin platelets on defective secondary aggregation in the Hermansky-Pudlak syndrome. A test for storage pool deficient platelets.

1972 • 58 citations

Platelet Dysfunction in Glycogen Storage Disease Type I

1973 • 58 citations

Relationship of Appearance of Adenosine Diphosphate, Fibrin Formation and Platelet Aggregation in the Haemostatic Plug in vivo

1965 • 58 citations

Actin‐linked regulation of the human platelet contractile system

1973 • 55 citations

Ultrastructural findings in storage pool disease and aspirin-like defects of platelets.

1973 • 55 citations

STORAGE OF 5-HYDROXYTRYPTAMINE IN MEGAKARYOCYTES

1972 • 55 citations

Collagen-Mediated Platelet Aggregation EFFECTS OF COLLAGEN MODIFICATION INVOLVING THE PROTEIN AND CARBOHYDRATE MOIETIES

1973 • 54 citations

SPONTANEOUS BRUISING ASSOCIATED WITH A DEFECT IN THE INTERACTION OF PLATELETS WITH CONNECTIVE TISSUE

1967 • 53 citations

Nucleotide and Serotonin Metabolism in Platelets With Defective Secondary Aggregation

1974 • 53 citations

Localization of 5‐Hydroxytryptamine in Blood Platelets: An Autoradiographic and Ultrastructural Study

1968 • 51 citations

A NEW FAMILIAL PLATELET DISEASE

1968 • 49 citations

Platelet Dysfunction — Differentiation of a Newly Recognized Primary Type from That Produced by Aspirin

1969 • 49 citations

Rough Endoplasmic Reticulum and Ribosomes in Blood Platelets

1971 • 48 citations

PLATELET DYSFUNCTION IN PRELEUKEMIC STATES AND IN VARIOUS TYPES OF LEUKEMIA

1972 • 48 citations

Factor VIII of Small Molecular Weight and its Aggregation

1974 • 47 citations

A congenital defect in platelet prostaglandin production associated with impaired hemostasis in storage pool disease

1973 • 47 citations

Deficiency of Glutathione Peroxidase Associated with High Levels of Reduced Glutathione in Glanzmann's Thrombasthenia

1972 • 46 citations

The Defect in Hemophilic and von Willebrand's Disease Plasmas Studied by a Recombination Technique

1974 • 45 citations

Von Willebrand's Disease Type B: A Newly Defined Bleeding Diathesis

1973 • 44 citations

PLATELETS: A PORTSMOUTH SYNDROME?

1967 • 44 citations

ULTRASTRUCTURAL DEFECTS IN CONGENITAL DISORDERS OF PLATELET FUNCTION*

1972 • 43 citations

Labile Aggregation Stimulating Substance (LASS): the Factor from Storage Pool Deficient Platelets Correcting Defective Aggregation and Release of Aspirin Treated Normal Platelets

1975 • 42 citations

Collagen-Induced Platelet Aggregation: Involvement of an Active Glycopeptide Fragment (α1-CB5)

1973 • 41 citations

Platelet Coagulant Activities in Thrombasthenia

1972 • 41 citations

Evidence that bovine factor VIII, not bovine fibrinogen, aggregates human platelets

1973 • 41 citations

EVIDENCE FOR A QUALITATIVE DEFECT IN FACTOR-VIII-RELATED ANTIGEN IN VON WILLEBRAND'S DISEASE

1974 • 40 citations

ABNORMALITIES IN PLATELET FUNCTION DUE TO DEFECTS IN THE RELEASE REACTION

1972 • 39 citations

Reactions of 14C-ADP and 14C-ATP With Washed Platelets From Rabbits

1971 • 38 citations

Exocytosis of secretory organelles from blood platelets incubated with cationic polypeptides.

1972 • 38 citations

Interaction of thrombasthenic platelets with subendothelium: Normal adhesion, absent aggregation

1975 • 38 citations

Relationship of Glucose Oxidation to Aggregation of Human Platelets

1973 • 37 citations

Platelets and Initiation of Intrinsic Clotting

1973 • 36 citations

The phospholipid and fatty acid composition of platelets in patients with primary defects of platelet function

1972 • 35 citations

Serotonin storage organelles in human megakaryocytes.

1971 • 31 citations

Biochemical Studies on the Regulation of Myocardial Contractility

1974 • 30 citations

Primary and Secondary Platelet Aggregation in Uraemia

1972 • 30 citations

Colchicine-binding Protein from Human Platelets and Its Effect on Muscle Myosin and Platelet Myosin-like Thrombosthenin-M

1971 • 26 citations

Guanidinosuccinic Acid on Human Platelet Effects of Exogenous Urea, Creatinine, and Aggregation In Vitro

1972 • 25 citations

Factor‐VIII Antigen and Platelet Retention in a Glass Bead Column

1973 • 25 citations

Platelet Factor 4 in Platelet Disorders-Storage Location and the Requirement of Endogenous ADP for Its Release

1973 • 25 citations

Possible Thrombosthenin Defect in Glanzmann’s Thrombasthenia

1972 • 23 citations

Properties of post-infusion factor VIII in Von Willebrand's disease

1974 • 23 citations

Incorporation of hypoxanthine into adenine and guanine nucleotides by human platelets

1975 • 23 citations

Familial bleeding tendency associated with microcytic platelets and impaired release of platelet adenosine diphosphate

1971 • 22 citations

The effect of aggregating agents on oxidative metabolism of rabbit platelets

1971 • 22 citations

Thrombin-Induced Increase in Intracellular Cyclic 3′,5′-Adenosine Monophosphate in Human Platelets

1972 • 21 citations

Familial Association of Thrombopathia and Antihemophilic Factor (AHF, Factor VIII) Deficiency

1972 • 21 citations

Hemolytic Disease and Thymic Function

1974 • 18 citations

Control of platelet actomyosin activity: Effect of ADP on superprecipitation and ATPase activity of human platelet actomyosin

1974 • 18 citations

Platelet‐Function Studies in Patients with Glucose‐6‐Phosphate Dehydrogenase Deficiency

1974 • 18 citations

The Release Reaction of Secretion: A General Basic Phenomenon Related to Phagocytosis/Pinocytosis

1969 • 17 citations

Synthesis and storage of nucleotides in blood platelets

1970 • 17 citations

Platelet Functional Abnormalities: A Report of Two Familial Defects in Interaction Between Collagen and Platelets and ADP Release

1971 • 17 citations

Platelets

1974 • 17 citations

Adenosine Triphosphate Cleavage during the G-Actin to F-Actin Transformation and the Binding of Adenosine Diphosphate to F-Actin

1964 • 16 citations

PLATELET ABNORMALITIES IN VON WILLEBRAND'S DISEASE*

1972 • 16 citations

A Syndrome of Platelet-release Abnormality and Mild Hemophilia

1974 • 15 citations

Oozing and Bruising Due to Abnormal Platelet Function (Thrombocytopathia)

1972 • 13 citations

QUALITATIVE PLATELET DISORDERS: CLASSIFICATION AND PATHOGENESIS

1972 • 11 citations

Reduced tissue factor (thromboplastin) activity in von Willebrand's disease

1974 • 10 citations

Platelets, Surfaces and Plasma Proteins in Platelet Adhesion

2015 • 2 citations

SYNTHESIS OF HIGH-MOLECULAR-WEIGHT ANTIHÆMOPHILIC FACTOR IN VON WILLEBRAND'S DISEASE

1974 • 2 citations