Nuclear Export of Map Kinase (ERK) Involves a Map Kinase Kinase (Mek-Dependent) Active Transport Mechanism

Mitogen-activated protein kinase pathways

1997 • 2,513 citations

The mitogen-activated protein kinase signal transduction pathway

1993 • 2,174 citations

CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals

1997 • 2,062 citations

Signal Transduction through MAP Kinase Cascades

1998 • 1,762 citations

Signal transduction via the MAP kinases: proceed at your own RSK.

1993 • 1,262 citations

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

1997 • 1,195 citations

Nuclear localization and regulation of erk- and rsk-encoded protein kinases.

1992 • 1,107 citations

The MAP kinase cascade is essential for diverse signal transduction pathways

1993 • 1,091 citations

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

1994 • 1,005 citations

Evidence for a Role of CRM1 in Signal-Mediated Nuclear Protein Export

1997 • 716 citations

Phosphorylation of the MAP Kinase ERK2 Promotes Its Homodimerization and Nuclear Translocation

1998 • 675 citations

Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

1993 • 668 citations

Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

1997 • 654 citations

Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6

1991 • 442 citations

Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase

1997 • 377 citations

MAP kinase by any other name smells just as sweet

1992 • 341 citations

Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus

1993 • 328 citations

Cytoplasmic Localization of Mitogen-activated Protein Kinase Kinase Directed by Its NH2-terminal, Leucine-rich Short Amino Acid Sequence, Which Acts as a Nuclear Export Signal

1996 • 326 citations

The molecular and cellular basis of affinity maturation in the antibody response

1992 • 278 citations

Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer

1999 • 264 citations

Nuclear Localization and Regulation of erk-and rsk-Encoded Protein Kinases

1992 • 246 citations

Conditionally Oncogenic Forms of the A-Raf and B-Raf Protein Kinases Display Different Biological and Biochemical Properties in NIH 3T3 Cells

1995 • 222 citations

Growth Factor–induced p42/p44 MAPK Nuclear Translocation and Retention Requires Both MAPK Activation and Neosynthesis of Nuclear Anchoring Proteins

1998 • 211 citations

Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation

1997 • 183 citations

Signaling in the Yeast Pheromone Response Pathway: Specific and High-Affinity Interaction of the Mitogen-Activated Protein (MAP) Kinases Kss1 and Fus3 with the Upstream MAP Kinase Kinase Ste7

1996 • 164 citations

Cytoplasmic localization of the mitogen-activated protein kinase activator MEK.

1994 • 102 citations

Nuclear Localization of Mitogen-activated Protein Kinase Kinase 1 (MKK1) Is Promoted by Serum Stimulation and G2-M Progression

1999 • 70 citations

Characterization of recombinant Xenopus MAP kinase kinases mutated at potential phosphorylation sites.

1994 • 57 citations

Activation of two Isoforms of Mitogen‐Activated Protein Kinase Kinase in Response to Epidermal Growth Factor and Nerve Growth Factor

1995 • 24 citations